Tstd1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Tstd1provided by MGI
Official Full Name: thiosulfate sulfurtransferase (rhodanese)-like domain containing 1provided by MGI
Primary source: MGI:MGI:3648482
See related: Ensembl:ENSMUSG00000103711 AllianceGenome:MGI:3648482
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: KAT; Gm4848; EG226654
Summary: Located in mitochondrion. Orthologous to human TSTD1 (thiosulfate sulfurtransferase like domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in colon adult (RPKM 151.2), duodenum adult (RPKM 49.7) and 5 other tissues See more
Orthologs: human all
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Genomic context

Location:: 1 H3; 1 79.41 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	1	NC_000067.7 (171246601..171247920)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	1	NC_000067.6 (171419033..171420352)

Chromosome 1 - NC_000067.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Integrative Analyses Reveal Tstd1 as a Potential Modulator of HDL Cholesterol and Mitochondrial Function in Mice.
Title: Integrative Analyses Reveal Tstd1 as a Potential Modulator of HDL Cholesterol and Mitochondrial Function in Mice.
compares human Tstd1 amino acid sequence to that of orthologs, including mouse.
Title: Identification and characterization of KAT, a novel gene preferentially expressed in several human cancer cell lines.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytoplasmic ribonucleoprotein granule	ISO Inferred from Sequence Orthology more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	HDA more info	PubMed

General protein information

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Preferred Names: thiosulfate:glutathione sulfurtransferase

NP_001157997.1

EC 2.8.1.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001164525.1 → NP_001157997.1 thiosulfate:glutathione sulfurtransferase

Status: VALIDATED

Source sequence(s)

AC087229, BY720852

Consensus CDS

CCDS48443.1

UniProtKB/TrEMBL

E9PY03

Related

ENSMUSP00000132771.2, ENSMUST00000171362.2

Conserved Domains (1) summary

cd01519
Location:25 → 130

RHOD_HSP67B2; Member of the Rhodanese Homology Domain superfamily. This CD includes the heat shock protein 67B2 of Drosophila melanogaster and other similar proteins, many of which are uncharacterized.