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    Mucl1 mucin-like 1 [ Mus musculus (house mouse) ]

    Gene ID: 20771, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Mucl1provided by MGI
    Official Full Name
    mucin-like 1provided by MGI
    Primary source
    MGI:MGI:98393
    See related
    Ensembl:ENSMUSG00000060311 AllianceGenome:MGI:98393
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Spt2; Spt-2
    Annotation information
    Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Mucl1 in Genome Data Viewer
    Location:
    15 F3; 15
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (103782189..103785764, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (103751923..103755498, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53237 Neighboring gene predicted gene, 53236 Neighboring gene predicted gene, 21178 Neighboring gene mucin-like 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Rapid evolution of variants in a rodent multigene family encoding salivary proteins. Dickinson DP, et al. Mol Biol Evol, 1989 Jan. PMID 2921944
    2. Genetic and tissue-specific variation in the expression of a closely linked murine multigene family on chromosome 15 that encodes salivary and lacrimal proteins. Dickinson DP, et al. Biochem Genet, 1989 Oct. PMID 2482730
    3. Genetic analysis of intestinal cholesterol absorption in inbred mice. Schwarz M, et al. J Lipid Res, 2001 Nov. PMID 11714849
    4. Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation. Patel VN, et al. Nat Commun, 2024 Aug 31. PMID 39217171, Free PMC Article
    5. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Clone Names

    • MGC102563

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    mucin-like 1
    Names
    salivary protein 2
    spot 2 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009268.1 → NP_033294.1  mucin-like 1 isoform Spt-2 precursor

      See identical proteins and their annotated locations for NP_033294.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and derives from a non-reference strain, DBA/2J. It encodes the Spt-2 protein (PMIDs 2482730, 2921944).
      Source sequence(s)
      M33975
      UniProtKB/TrEMBL
      Q62265, Q91X55
      Conserved Domains (1) summary
      PRK08581
      Location:21 → 165
      PRK08581; N-acetylmuramoyl-L-alanine amidase; Validated

    RNA

    1. NR_126081.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1, non-coding) contains multiple mismatches and indels relative to variant 1, and derives from the reference strain, C57BL/6J. This transcript may not be produced and is unlikely to encode a protein (PMIDs 2482730, 2921944).
      Source sequence(s)
      FO082317
      Related
      ENSMUST00000226484.2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      103782189..103785764 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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