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    Ceacam23 CEA cell adhesion moleculen23 [ Mus musculus (house mouse) ]

    Gene ID: 381852, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ceacam23provided by MGI
    Official Full Name
    CEA cell adhesion moleculen23provided by MGI
    Primary source
    MGI:MGI:3647191
    See related
    Ensembl:ENSMUSG00000078793 AllianceGenome:MGI:3647191
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm5155; EG381852
    Summary
    Predicted to be involved in T cell activation and immune response. Predicted to be located in apical plasma membrane and cytosol. Predicted to be active in external side of plasma membrane. Orthologous to human CEACAM7 (CEA cell adhesion molecule 7). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward placenta adult (RPKM 67.0) See more
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    Genomic context

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    See Ceacam23 in Genome Data Viewer
    Location:
    7 A2; 7 9.15 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (17605669..17652968)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (17871744..17919043)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase A pseudogene 7_184.1 Neighboring gene CEA cell adhesion molecule 14 Neighboring gene STARR-seq mESC enhancer starr_18157 Neighboring gene STARR-seq mESC enhancer starr_18158 Neighboring gene STARR-seq mESC enhancer starr_18159 Neighboring gene STARR-seq mESC enhancer starr_18160 Neighboring gene CEA cell adhesion molecule 11 Neighboring gene MHC I like leukocyte 2 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in T cell activation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC381852

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001378684.1 → NP_001365613.1  uncharacterized protein LOC381852 precursor

      Status: VALIDATED

      Source sequence(s)
      AC134475, AC140257
      UniProtKB/TrEMBL
      A0A3Q4EGJ1
      Related
      ENSMUSP00000156991.2, ENSMUST00000072381.14
      Conserved Domains (4) summary
      cd00096
      Location:631 → 633
      Ig; Ig strand A [structural motif]
      cd05740
      Location:979 → 1065
      IgI_hCEACAM_2_4_6_like; Immunoglobulin (Ig)-like domain of human carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM) domains 2, 4, and 6, and similar domains
      cd05774
      Location:751 → 853
      IgV_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      cl11960
      Location:630 → 734
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      17605669..17652968
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006540458.1 → XP_006540521.1  uncharacterized protein LOC381852 isoform X2

      Conserved Domains (3) summary
      smart00408
      Location:874 → 935
      IGc2; Immunoglobulin C-2 Type
      cd05774
      Location:751 → 853
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      cl11960
      Location:630 → 734
      Ig; Immunoglobulin domain

    2. XM_006540461.2 → XP_006540524.1  uncharacterized protein LOC381852 isoform X5

      Conserved Domains (3) summary
      smart00408
      Location:872 → 933
      IGc2; Immunoglobulin C-2 Type
      cd05774
      Location:631 → 733
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      cl11960
      Location:510 → 614
      Ig; Immunoglobulin domain

    3. XM_006540459.2 → XP_006540522.1  uncharacterized protein LOC381852 isoform X3

      Conserved Domains (3) summary
      smart00408
      Location:872 → 933
      IGc2; Immunoglobulin C-2 Type
      cd05774
      Location:631 → 733
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      cl11960
      Location:510 → 614
      Ig; Immunoglobulin domain

    4. XM_006540457.1 → XP_006540520.1  uncharacterized protein LOC381852 isoform X1

      Conserved Domains (3) summary
      smart00408
      Location:875 → 936
      IGc2; Immunoglobulin C-2 Type
      cd05774
      Location:634 → 736
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      cl11960
      Location:513 → 617
      Ig; Immunoglobulin domain

    5. XM_006540462.1 → XP_006540525.1  uncharacterized protein LOC381852 isoform X6

      Conserved Domains (3) summary
      smart00408
      Location:755 → 816
      IGc2; Immunoglobulin C-2 Type
      cd05774
      Location:514 → 616
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      cl11960
      Location:393 → 497
      Ig; Immunoglobulin domain

    6. XM_006540460.2 → XP_006540523.1  uncharacterized protein LOC381852 isoform X4

      Conserved Domains (3) summary
      smart00408
      Location:872 → 933
      IGc2; Immunoglobulin C-2 Type
      cd05774
      Location:631 → 733
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      cl11960
      Location:510 → 614
      Ig; Immunoglobulin domain

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001034877.2: Suppressed sequence

      Description
      NM_001034877.2: This RefSeq was temporarily suppressed because the CDS was partial.
    Nucleotide Protein Strain
    Heading Accession and Version

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