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    S100z S100 calcium binding protein, zeta [ Mus musculus (house mouse) ]

    Gene ID: 268686, updated on 9-Dec-2024

    Summary

    Official Symbol
    S100zprovided by MGI
    Official Full Name
    S100 calcium binding protein, zetaprovided by MGI
    Primary source
    MGI:MGI:2685471
    See related
    Ensembl:ENSMUSG00000021679 AllianceGenome:MGI:2685471
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm625
    Summary
    Predicted to enable calcium ion binding activity; calcium-dependent protein binding activity; and protein homodimerization activity. Orthologous to human S100Z (S100 calcium binding protein Z). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in genital fat pad adult (RPKM 6.1) and testis adult (RPKM 0.5) See more
    Orthologs
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    Genomic context

    See S100z in Genome Data Viewer
    Location:
    13 D1; 13 49.53 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (95613809..95615163, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (95477301..95478655, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene angiogenic factor with G patch and FHA domains 1 Neighboring gene STARR-positive B cell enhancer ABC_E7266 Neighboring gene STARR-seq mESC enhancer starr_35322 Neighboring gene STARR-positive B cell enhancer ABC_E3093 Neighboring gene STARR-seq mESC enhancer starr_35323 Neighboring gene corticotropin releasing hormone binding protein Neighboring gene predicted gene, 52025 Neighboring gene F2R like trypsin receptor 1 Neighboring gene STARR-seq mESC enhancer starr_35326 Neighboring gene predicted gene, 53807 Neighboring gene predicted gene, 32640

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables calcium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables calcium-dependent protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081159.1NP_001074628.1  protein S100-Z

      See identical proteins and their annotated locations for NP_001074628.1

      Status: PROVISIONAL

      Source sequence(s)
      AC159263
      Consensus CDS
      CCDS36752.1
      UniProtKB/TrEMBL
      B9EJL3
      Related
      ENSMUSP00000022186.4, ENSMUST00000022186.5
      Conserved Domains (2) summary
      pfam13499
      Location:2579
      EF-hand_7; EF-hand domain pair
      cl08302
      Location:193
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      95613809..95615163 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)