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    Zscan29 zinc finger SCAN domains 29 [ Mus musculus (house mouse) ]

    Gene ID: 99334, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zscan29provided by MGI
    Official Full Name
    zinc finger SCAN domains 29provided by MGI
    Primary source
    MGI:MGI:2139317
    See related
    Ensembl:ENSMUSG00000050619 AllianceGenome:MGI:2139317
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Zfp690
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in bladder; telencephalon ventricular layer; and testis. Orthologous to human ZSCAN29 (zinc finger and SCAN domain containing 29). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 2.7), bladder adult (RPKM 2.3) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zscan29 in Genome Data Viewer
    Location:
    2 E5; 2 60.37 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (120988754..121001623, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (121158273..121171148, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 23858 Neighboring gene leucine carboxyl methyltransferase 2 Neighboring gene adenosine deaminase-like Neighboring gene tubulin, gamma complex component 4 Neighboring gene transformation related protein 53 binding protein 1 Neighboring gene STARR-seq mESC enhancer starr_05522 Neighboring gene STARR-seq mESC enhancer starr_05523 Neighboring gene STARR-positive B cell enhancer ABC_E2640 Neighboring gene STARR-seq mESC enhancer starr_05524 Neighboring gene STARR-positive B cell enhancer ABC_E5972 Neighboring gene STARR-seq mESC enhancer starr_05525 Neighboring gene microtubule-associated protein 1 A Neighboring gene diphosphoinositol pentakisphosphate kinase 1 Neighboring gene STARR-positive B cell enhancer ABC_E640

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray. Nishimura M, et al. DNA Res, 2004 Oct 31. PMID 15747579
    2. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC117957

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger and SCAN domain-containing protein 29
    Names
    zinc finger protein 690

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001290819.2 → NP_001277748.1  zinc finger and SCAN domain-containing protein 29 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (a).
      Source sequence(s)
      AL845479
      Consensus CDS
      CCDS71123.1
      UniProtKB/TrEMBL
      A2ARU5
      Related
      ENSMUSP00000106289.3, ENSMUST00000110661.9
      Conserved Domains (7) summary
      smart00431
      Location:13 → 123
      SCAN; leucine rich region
      COG5048
      Location:663 → 823
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:667 → 687
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:777 → 799
      zf-C2H2; Zinc finger, C2H2 type
      pfam02023
      Location:13 → 101
      SCAN; SCAN domain
      pfam13465
      Location:735 → 760
      zf-H2C2_2; Zinc-finger double domain
      pfam13837
      Location:399 → 480
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    2. NM_001290820.2 → NP_001277749.1  zinc finger and SCAN domain-containing protein 29 isoform b

      See identical proteins and their annotated locations for NP_001277749.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) initiates translation at an alternate start codon, lacks two 3' exons but instead contains an alternate 3' terminal exon, and it thus differs in its 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (b) has distinct N- and C-termini and is shorter than isoform a.
      Source sequence(s)
      AL845479
      UniProtKB/TrEMBL
      Q3SYJ9, Q8BGW7
      Conserved Domains (1) summary
      pfam13837
      Location:132 → 213
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    3. NM_001424739.1 → NP_001411668.1  zinc finger and SCAN domain-containing protein 29 isoform c

      Status: VALIDATED

      Source sequence(s)
      AL845479

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      120988754..121001623 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_178889.4: Suppressed sequence

      Description
      NM_178889.4: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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