Fggy FGGY carbohydrate kinase domain containing [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Fggyprovided by RGD
Official Full Name: FGGY carbohydrate kinase domain containingprovided by RGD
Primary source: RGD:1359429
See related: EnsemblRapid:ENSRNOG00000008907 AllianceGenome:RGD:1359429
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable D-ribulokinase activity. Predicted to be involved in carbohydrate phosphorylation; neuron cellular homeostasis; and pentose metabolic process. Predicted to be active in cytoplasm. Orthologous to human FGGY (FGGY carbohydrate kinase domain containing). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Liver (RPKM 76.7), Kidney (RPKM 62.2) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 5q33

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	5	NC_086023.1 (115514573..115901713)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	5	NC_051340.1 (110398866..110786019)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	5	NC_005104.4 (114516860..114901571)

Chromosome 5 - NC_086023.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

AU047087 (e-PCR)
- UniSTS:110854

D5Rat155 (e-PCR), detects polymorphism
- UniSTS:227875

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables D-ribulokinase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in carbohydrate phosphorylation	ISO Inferred from Sequence Orthology more info
involved_in neuron cellular homeostasis	ISO Inferred from Sequence Orthology more info
involved_in pentose metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: FGGY carbohydrate kinase domain-containing protein

NP_001013954.2

EC 2.7.1.-

EC 2.7.1.47

XP_006238472.1

EC 2.7.1.-

EC 2.7.1.47

XP_017448749.1

EC 2.7.1.-

EC 2.7.1.47

XP_017448750.1

EC 2.7.1.-

EC 2.7.1.47

XP_038965461.1

EC 2.7.1.-

EC 2.7.1.47

XP_038965462.2

EC 2.7.1.-

EC 2.7.1.47

XP_038965464.1

EC 2.7.1.-

EC 2.7.1.47

XP_063143446.1

EC 2.7.1.-

EC 2.7.1.47

XP_063143447.1

EC 2.7.1.-

EC 2.7.1.47

XP_063143448.1

EC 2.7.1.-

EC 2.7.1.47

XP_063143449.1

EC 2.7.1.-

EC 2.7.1.47

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001013932.2 → NP_001013954.2 FGGY carbohydrate kinase domain-containing protein

See identical proteins and their annotated locations for NP_001013954.2

Status: VALIDATED

Source sequence(s)

BC090077, CB316436

UniProtKB/TrEMBL

F1LSP9

Conserved Domains (1) summary

cd07782
Location:11 → 545

FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086023.1 Reference GRCr8

Range

115514573..115901713

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017593260.3 → XP_017448749.1 FGGY carbohydrate kinase domain-containing protein isoform X1

UniProtKB/TrEMBL

F1LSP9

Related

ENSRNOP00000011767.6, ENSRNOT00000011767.7

Conserved Domains (1) summary

cd07782
Location:11 → 545

FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases
XM_017593261.3 → XP_017448750.1 FGGY carbohydrate kinase domain-containing protein isoform X1

UniProtKB/TrEMBL

F1LSP9

Conserved Domains (1) summary

cd07782
Location:11 → 545

FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases
XM_063287376.1 → XP_063143446.1 FGGY carbohydrate kinase domain-containing protein isoform X3

UniProtKB/TrEMBL

F1LSP9

Related

ENSRNOP00000109575.1, ENSRNOT00000145188.1
XM_039109534.2 → XP_038965462.2 FGGY carbohydrate kinase domain-containing protein isoform X2

UniProtKB/TrEMBL

A0A8I6AN02
XM_039109533.2 → XP_038965461.1 FGGY carbohydrate kinase domain-containing protein isoform X1

UniProtKB/TrEMBL

F1LSP9

Related

ENSRNOP00000098720.1, ENSRNOT00000126021.1

Conserved Domains (1) summary

cd07782
Location:11 → 545

FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases
XM_006238410.5 → XP_006238472.1 FGGY carbohydrate kinase domain-containing protein isoform X1

See identical proteins and their annotated locations for XP_006238472.1

UniProtKB/TrEMBL

F1LSP9

Conserved Domains (1) summary

cd07782
Location:11 → 545

FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases
XM_039109536.2 → XP_038965464.1 FGGY carbohydrate kinase domain-containing protein isoform X5

UniProtKB/TrEMBL

A6JRI3

Conserved Domains (1) summary

cl17037
Location:2 → 336

NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
XM_063287379.1 → XP_063143449.1 FGGY carbohydrate kinase domain-containing protein isoform X6
XM_063287378.1 → XP_063143448.1 FGGY carbohydrate kinase domain-containing protein isoform X5

UniProtKB/TrEMBL

A6JRI3
XM_063287377.1 → XP_063143447.1 FGGY carbohydrate kinase domain-containing protein isoform X4