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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001031853.5 → NP_001027024.3 protein inscuteable homolog isoform a
See identical proteins and their annotated locations for NP_001027024.3
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (a).
- Source sequence(s)
-
AB236159, DY654442
- Consensus CDS
-
CCDS41621.1
- UniProtKB/Swiss-Prot
- A0PJX5, Q1MX18, Q1MX19, Q3C1V6, Q4AC95, Q4AC96, Q4AC97, Q4AC98
- UniProtKB/TrEMBL
-
A0A0A0MSI1
- Related
- ENSP00000368872.3, ENST00000379554.7
- Conserved Domains (2) summary
-
- cd00020
Location:454 → 562
- ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
- pfam16748
Location:70 → 113
- INSC_LBD; Inscuteable LGN-binding domain
-
NM_001042536.3 → NP_001036001.1 protein inscuteable homolog isoform b
See identical proteins and their annotated locations for NP_001036001.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) has an alternate exon at the 5' end, which results in a downstream start codon, compared to variant 1. The resulting isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2 and 3 encode the same isoform b.
- Source sequence(s)
-
AB236158, AC090744, BU147420, DY654442
- Consensus CDS
-
CCDS41622.1
- UniProtKB/TrEMBL
-
A0A0A0MSI1
- Related
- ENSP00000368874.3, ENST00000379556.8
- Conserved Domains (2) summary
-
- cd00020
Location:407 → 515
- ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
- pfam16748
Location:23 → 66
- INSC_LBD; Inscuteable LGN-binding domain
-
NM_001278313.2 → NP_001265242.1 protein inscuteable homolog isoform b
See identical proteins and their annotated locations for NP_001265242.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) lacks an exon at the 5' end but has an alternate segment, which results in a downstream start codon, compared to variant 1. The resulting isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2 and 3 encode the same isoform b.
- Source sequence(s)
-
AB231745, AB236158, BC127700, DY654442
- Consensus CDS
-
CCDS41622.1
- UniProtKB/TrEMBL
-
A0A0A0MSI1
- Related
- ENSP00000436194.1, ENST00000530161.5
- Conserved Domains (2) summary
-
- cd00020
Location:407 → 515
- ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
- pfam16748
Location:23 → 66
- INSC_LBD; Inscuteable LGN-binding domain
-
NM_001278314.2 → NP_001265243.1 protein inscuteable homolog isoform c
Status: VALIDATED
- Description
- Transcript Variant: This variant (4) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. The resulting isoform (c) is shorter at the N-terminus and has an additional internal segment, compared to isoform a.
- Source sequence(s)
-
AB236158, AC090744, BC127700, DY654442
- UniProtKB/TrEMBL
-
A0A0A0MSI1
- Related
- ENSP00000389161.2, ENST00000424273.5
- Conserved Domains (2) summary
-
- cd00020
Location:442 → 550
- ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
- pfam16748
Location:23 → 66
- INSC_LBD; Inscuteable LGN-binding domain
-
NM_001278315.2 → NP_001265244.1 protein inscuteable homolog isoform d
See identical proteins and their annotated locations for NP_001265244.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (5) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. The resulting isoform (d) is shorter at the N-terminus and has a distinct C-terminus, compared to isoform a.
- Source sequence(s)
-
AB236158, BC127700, DY654442
- Consensus CDS
-
CCDS60735.1
- UniProtKB/TrEMBL
-
A0A0A0MSI1
- Related
- ENSP00000435022.1, ENST00000528567.5
- Conserved Domains (1) summary
-
- pfam16748
Location:23 → 66
- INSC_LBD; Inscuteable LGN-binding domain
-
NM_001278316.2 → NP_001265245.1 protein inscuteable homolog isoform e
Status: VALIDATED
- Description
- Transcript Variant: This variant (6) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. The resulting isoform (e) is shorter at the N-terminus and lacks an internal segment, compared to isoform a.
- Source sequence(s)
-
AB236158, BC117561, BC127700, DY654442
- Consensus CDS
-
CCDS60736.1
- UniProtKB/TrEMBL
-
A0A0A0MSI1
- Related
- ENSP00000436113.1, ENST00000525218.1
- Conserved Domains (2) summary
-
- cd00020
Location:365 → 473
- ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
- pfam16748
Location:23 → 66
- INSC_LBD; Inscuteable LGN-binding domain