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    Mrpl55 mitochondrial ribosomal protein L55 [ Mus musculus (house mouse) ]

    Gene ID: 67212, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mrpl55provided by MGI
    Official Full Name
    mitochondrial ribosomal protein L55provided by MGI
    Primary source
    MGI:MGI:1914462
    See related
    Ensembl:ENSMUSG00000036860 AllianceGenome:MGI:1914462
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    L55mt; MRP-L55; 2810038N09Rik
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human MRPL55 (mitochondrial ribosomal protein L55). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in heart adult (RPKM 24.1), testis adult (RPKM 23.1) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Mrpl55 in Genome Data Viewer
    Location:
    11 B1.3; 11 37.05 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (59093312..59096964)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (59202486..59206138)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene guanylate kinase 1 Neighboring gene STARR-positive B cell enhancer ABC_E6990 Neighboring gene RIKEN cDNA 2610507I01 gene Neighboring gene STARR-positive B cell enhancer ABC_E5232 Neighboring gene RIKEN cDNA 2310033P09 gene Neighboring gene STARR-positive B cell enhancer ABC_E3955 Neighboring gene ARF GTPase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Expression analysis of mammalian mitochondrial ribosomal protein genes. Cheong A, et al. Gene Expr Patterns, 2020 Dec. PMID 32987154, Free PMC Article
    2. In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics. Distler U, et al. Proteomics, 2014 Nov. PMID 25211037
    3. Structure of the large ribosomal subunit from human mitochondria. Brown A, et al. Science, 2014 Nov 7. PMID 25278503, Free PMC Article
    4. Structure and Function of the Mitochondrial Ribosome. Greber BJ, et al. Annu Rev Biochem, 2016 Jun 2. PMID 27023846
    5. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of mitochondrial large ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of mitochondrial large ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    large ribosomal subunit protein mL55
    Names
    39S ribosomal protein L55, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001302334.2 → NP_001289263.1  large ribosomal subunit protein mL55 isoform 1

      See identical proteins and their annotated locations for NP_001289263.1

      Status: VALIDATED

      Source sequence(s)
      AK012143, AL645854, AV162288, BE652161, BQ031624, BY228808
      Consensus CDS
      CCDS78955.1
      UniProtKB/Swiss-Prot
      Q9CZ83
      Related
      ENSMUSP00000104412.4, ENSMUST00000108784.4
      Conserved Domains (1) summary
      pfam09776
      Location:17 → 131
      Mitoc_L55; Mitochondrial ribosomal protein L55

    2. NM_001302335.2 → NP_001289264.1  large ribosomal subunit protein mL55 isoform 1

      See identical proteins and their annotated locations for NP_001289264.1

      Status: VALIDATED

      Source sequence(s)
      AK012143, AV162288, BE652161, BQ031624, BY228808, CA325878
      Consensus CDS
      CCDS78955.1
      UniProtKB/Swiss-Prot
      Q9CZ83
      Related
      ENSMUSP00000104415.3, ENSMUST00000108787.9
      Conserved Domains (1) summary
      pfam09776
      Location:17 → 131
      Mitoc_L55; Mitochondrial ribosomal protein L55

    3. NM_001302336.2 → NP_001289265.1  large ribosomal subunit protein mL55 isoform 2 precursor

      See identical proteins and their annotated locations for NP_001289265.1

      Status: VALIDATED

      Source sequence(s)
      AK012143, AK012885, AV162288, BY228808
      Consensus CDS
      CCDS24763.1
      UniProtKB/Swiss-Prot
      Q8R030, Q9CZ83
      Related
      ENSMUSP00000048814.6, ENSMUST00000045697.12
      Conserved Domains (1) summary
      pfam09776
      Location:10 → 124
      Mitoc_L55; Mitochondrial ribosomal protein L55

    4. NM_001362908.1 → NP_001349837.1  large ribosomal subunit protein mL55 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL645854
      Consensus CDS
      CCDS78955.1
      Related
      ENSMUSP00000104414.2, ENSMUST00000108786.8
      Conserved Domains (1) summary
      pfam09776
      Location:17 → 131
      Mitoc_L55; Mitochondrial ribosomal protein L55

    5. NM_001362909.1 → NP_001349838.1  large ribosomal subunit protein mL55 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AL645854
      Consensus CDS
      CCDS24763.1
      UniProtKB/Swiss-Prot
      Q8R030, Q9CZ83
      Conserved Domains (1) summary
      pfam09776
      Location:10 → 124
      Mitoc_L55; Mitochondrial ribosomal protein L55

    6. NM_026035.4 → NP_080311.1  large ribosomal subunit protein mL55 isoform 2 precursor

      See identical proteins and their annotated locations for NP_080311.1

      Status: VALIDATED

      Source sequence(s)
      AK012143, AK012885, AV162288, BB068394, BY228808
      Consensus CDS
      CCDS24763.1
      UniProtKB/Swiss-Prot
      Q8R030, Q9CZ83
      Related
      ENSMUSP00000104413.2, ENSMUST00000108785.2
      Conserved Domains (1) summary
      pfam09776
      Location:10 → 124
      Mitoc_L55; Mitochondrial ribosomal protein L55

    RNA

    1. NR_126101.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AA061936, AK012143, AV162288, BY228808

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      59093312..59096964
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030246239.2 → XP_030102099.1  large ribosomal subunit protein mL55 isoform X2

      UniProtKB/Swiss-Prot
      Q8R030, Q9CZ83
      Conserved Domains (1) summary
      pfam09776
      Location:10 → 124
      Mitoc_L55; Mitochondrial ribosomal protein L55

    2. XM_030246240.2 → XP_030102100.1  large ribosomal subunit protein mL55 isoform X2

      UniProtKB/Swiss-Prot
      Q8R030, Q9CZ83
      Conserved Domains (1) summary
      pfam09776
      Location:10 → 124
      Mitoc_L55; Mitochondrial ribosomal protein L55

    3. XM_006533976.4 → XP_006534039.1  large ribosomal subunit protein mL55 isoform X1

      See identical proteins and their annotated locations for XP_006534039.1

      UniProtKB/Swiss-Prot
      Q9CZ83
      Conserved Domains (1) summary
      pfam09776
      Location:17 → 131
      Mitoc_L55; Mitochondrial ribosomal protein L55

    4. XM_030246241.1 → XP_030102101.1  large ribosomal subunit protein mL55 isoform X2

      UniProtKB/Swiss-Prot
      Q8R030, Q9CZ83
      Conserved Domains (1) summary
      pfam09776
      Location:10 → 124
      Mitoc_L55; Mitochondrial ribosomal protein L55

    5. XM_006533975.5 → XP_006534038.1  large ribosomal subunit protein mL55 isoform X1

      See identical proteins and their annotated locations for XP_006534038.1

      UniProtKB/Swiss-Prot
      Q9CZ83
      Conserved Domains (1) summary
      pfam09776
      Location:17 → 131
      Mitoc_L55; Mitochondrial ribosomal protein L55
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CZ83.1 GenPept UniProtKB/Swiss-Prot:Q9CZ83

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