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    Ccdc14 coiled-coil domain containing 14 [ Mus musculus (house mouse) ]

    Gene ID: 239839, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ccdc14provided by MGI
    Official Full Name
    coiled-coil domain containing 14provided by MGI
    Primary source
    MGI:MGI:2443448
    See related
    Ensembl:ENSMUSG00000022833 AllianceGenome:MGI:2443448
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    G630039H03Rik
    Summary
    Predicted to be involved in protein localization to centrosome. Predicted to be located in centrosome. Predicted to be active in centriolar satellite. Orthologous to human CCDC14 (coiled-coil domain containing 14). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in CNS E11.5 (RPKM 3.3), testis adult (RPKM 2.7) and 26 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ccdc14 in Genome Data Viewer
    Location:
    16 B3; 16 24.46 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (34510940..34545574)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (34690557..34725204)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene kalirin, RhoGEF kinase Neighboring gene STARR-seq mESC enhancer starr_40723 Neighboring gene STARR-seq mESC enhancer starr_40724 Neighboring gene predicted gene, 41448 Neighboring gene STARR-seq mESC enhancer starr_40725 Neighboring gene STARR-positive B cell enhancer ABC_E5539 Neighboring gene ropporin, rhophilin associated protein 1 Neighboring gene predicted gene, 35150 Neighboring gene STARR-seq mESC enhancer starr_40726 Neighboring gene myosin, light polypeptide kinase Neighboring gene RIKEN cDNA 1700119H24 gene Neighboring gene STARR-seq mESC enhancer starr_40727 Neighboring gene predicted gene, 53951

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo. Evsikov AV, et al. Genes Dev, 2006 Oct 1. PMID 17015433, Free PMC Article
    2. An Interaction Landscape of Ubiquitin Signaling. Zhang X, et al. Mol Cell, 2017 Mar 2. PMID 28190767
    3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
    4. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein localization to centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein localization to centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in centriolar satellite IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in centriolar satellite IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 14

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172824.4 → NP_766412.3  coiled-coil domain-containing protein 14

      Status: VALIDATED

      Source sequence(s)
      AC154456
      Consensus CDS
      CCDS49837.1
      UniProtKB/Swiss-Prot
      Q8BJ89, Q8K2J4
      UniProtKB/TrEMBL
      A0A338P6V9
      Related
      ENSMUSP00000156124.2, ENSMUST00000231609.2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      34510940..34545574
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036159922.1 → XP_036015815.1  coiled-coil domain-containing protein 14 isoform X1

      Conserved Domains (1) summary
      pfam15254
      Location:96 → 627
      CCDC14; Coiled-coil domain-containing protein 14

    2. XM_011245891.4 → XP_011244193.1  coiled-coil domain-containing protein 14 isoform X2

      See identical proteins and their annotated locations for XP_011244193.1

      Conserved Domains (1) summary
      pfam15254
      Location:96 → 510
      CCDC14; Coiled-coil domain-containing protein 14

    3. XM_030249111.1 → XP_030104971.1  coiled-coil domain-containing protein 14 isoform X3

      Conserved Domains (1) summary
      pfam15254
      Location:2 → 498
      CCDC14; Coiled-coil domain-containing protein 14

    RNA

    1. XR_384564.4 RNA Sequence

    2. XR_003951790.2 RNA Sequence

    3. XR_004939191.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8K2J4.3 GenPept UniProtKB/Swiss-Prot:Q8K2J4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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