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    IGLJ3 immunoglobulin lambda joining 3 [ Homo sapiens (human) ]

    Gene ID: 28831, updated on 10-Dec-2024

    Summary

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    Official Symbol
    IGLJ3provided by HGNC
    Official Full Name
    immunoglobulin lambda joining 3provided by HGNC
    Primary source
    HGNC:HGNC:5865
    See related
    IMGT/GENE-DB:IGLJ3; AllianceGenome:HGNC:5865
    Gene type
    other
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    J3
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    Genomic context

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    See IGLJ3 in Genome Data Viewer
    Location:
    22q11.22
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (22904988..22905025)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (23327897..23327934)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (23247168..23247205)

    Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene immunoglobulin lambda locus Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18727 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18728 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18729 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18730 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13527 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18731 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18732 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18733 Neighboring gene immunoglobulin lambda joining 2 Neighboring gene immunoglobulin lambda constant 2 Neighboring gene immunoglobulin lambda constant 3 (Kern-Oz+ marker) Neighboring gene immunoglobulin lambda joining 4 (non-functional)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Distinctive serologic, chemical, and molecular properties of human lambda IV light chains. Eulitz M, et al. J Immunol, 1995 Apr 1. PMID 7897210
    2. V-region and class specific RT-PCR amplification of human immunoglobulin heavy and light chain genes from B-cell lines. Watkins BA, et al. Scand J Immunol, 1995 Oct. PMID 7569777
    3. Human lambda light chain locus: organization and DNA sequences of three genomic J regions. Udey JA, et al. Immunogenetics, 1987. PMID 3102359
    4. The anti-DNA-associated idiotype 8.12 is encoded by the V lambda II gene family and maps to the vicinity of L chain CDR1. Paul E, et al. J Immunol, 1992 Dec 1. PMID 1431128
    5. V lambda and J lambda-C lambda gene segments of the human immunoglobulin lambda light chain locus are separated by 14 kb and rearrange by a deletion mechanism. Combriato G, et al. Eur J Immunol, 1991 Jun. PMID 1904362

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_000002.1 

      Range
      871152..871189
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

      Range
      22904988..22905025
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060946.1 Alternate T2T-CHM13v2.0

      Range
      23327897..23327934
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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