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    DLG5-AS1 DLG5 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 100128292, updated on 10-Dec-2024

    Summary

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    Official Symbol
    DLG5-AS1provided by HGNC
    Official Full Name
    DLG5 antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:45109
    See related
    AllianceGenome:HGNC:45109
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
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    Genomic context

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    See DLG5-AS1 in Genome Data Viewer
    Location:
    10q22.3
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (77926812..77929825)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (78795863..78798876)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (79686570..79689583)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene discs large MAGUK scaffold protein 5 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:79649557-79650232 Neighboring gene uncharacterized LOC101929347 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:79651583-79652256 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:79660915-79661442 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:79661443-79661970 Neighboring gene Sharpr-MPRA regulatory region 4447 Neighboring gene NFE2L2 motif-containing MPRA enhancers 69 and 123 Neighboring gene Sharpr-MPRA regulatory region 2984 Neighboring gene RNA, 7SL, cytoplasmic 284, pseudogene Neighboring gene ReSE screen-validated silencer GRCh37_chr10:79688206-79688382 Neighboring gene Sharpr-MPRA regulatory region 2866 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:79707975-79708512 Neighboring gene H3K27ac-H3K4me1 hESC enhancers GRCh37_chr10:79708513-79709050 and GRCh37_chr10:79709051-79709588 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:79730866-79731376 Neighboring gene H2A.Z histone pseudogene 5 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr10:79743812-79745011 Neighboring gene RNA polymerase III subunit A Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:79784551-79785750 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3612

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. LncRNA DLG5-AS1 facilitates breast cancer cell proliferation and invasion by promoting EZH2-mediated transcriptional silencing of SFRP1. Cai Y, et al. Arch Biochem Biophys, 2024 Jun. PMID 38677505
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LncRNA DLG5-AS1 facilitates breast cancer cell proliferation and invasion by promoting EZH2-mediated transcriptional silencing of SFRP1.
      Title: LncRNA DLG5-AS1 facilitates breast cancer cell proliferation and invasion by promoting EZH2-mediated transcriptional silencing of SFRP1.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Clone Names

    • FLJ37010

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_024585.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AK094329, AL391421, BM981914, BU928573

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      77926812..77929825
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      78795863..78798876
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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