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    Lrrc69 leucine rich repeat containing 69 [ Mus musculus (house mouse) ]

    Gene ID: 73314, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Lrrc69provided by MGI
    Official Full Name
    leucine rich repeat containing 69provided by MGI
    Primary source
    MGI:MGI:1920564
    See related
    Ensembl:ENSMUSG00000023151 AllianceGenome:MGI:1920564
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700034K16Rik
    Summary
    Predicted to be involved in intracellular signal transduction. Orthologous to human LRRC69 (leucine rich repeat containing 69). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in testis adult (RPKM 1.4) and cerebellum adult (RPKM 0.1) See more
    Orthologs
    human all
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    Genomic context

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    See Lrrc69 in Genome Data Viewer
    Location:
    4 A1; 4 6.3 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (14623622..14808379, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (14623622..14808379, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene myosin, light polypeptide 6, alkali, smooth muscle and non-muscle pseudogene Neighboring gene STARR-seq mESC enhancer starr_09633 Neighboring gene STARR-seq mESC enhancer starr_09634 Neighboring gene STARR-seq mESC enhancer starr_09635 Neighboring gene solute carrier family 26, member 7 Neighboring gene STARR-seq mESC enhancer starr_09636 Neighboring gene STARR-seq mESC enhancer starr_09637 Neighboring gene STARR-positive B cell enhancer ABC_E6153 Neighboring gene OTU domain containing 6B Neighboring gene phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 69

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028499.2 → NP_082775.1  leucine-rich repeat-containing protein 69

      See identical proteins and their annotated locations for NP_082775.1

      Status: PROVISIONAL

      Source sequence(s)
      AK161371
      Consensus CDS
      CCDS38696.1
      UniProtKB/Swiss-Prot
      Q9D9Q0
      Related
      ENSMUSP00000103911.2, ENSMUST00000108276.2
      Conserved Domains (3) summary
      cd00116
      Location:30 → 211
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:16 → 38
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:83 → 142
      LRR_8; Leucine rich repeat

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      14623622..14808379 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030253831.1 → XP_030109691.1  leucine-rich repeat-containing protein 69 isoform X1

      Conserved Domains (2) summary
      COG4886
      Location:16 → 303
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:44 → 66
      LRR_RI; leucine-rich repeat [structural motif]

    2. XM_030253832.2 → XP_030109692.1  leucine-rich repeat-containing protein 69 isoform X1

      Conserved Domains (2) summary
      COG4886
      Location:16 → 303
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:44 → 66
      LRR_RI; leucine-rich repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D9Q0.1 GenPept UniProtKB/Swiss-Prot:Q9D9Q0

    Gene LinkOut

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