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    Or8b12b olfactory receptor family 8 subfamily B member 12B [ Mus musculus (house mouse) ]

    Gene ID: 258744, updated on 9-Dec-2024

    Summary

    Official Symbol
    Or8b12bprovided by MGI
    Official Full Name
    olfactory receptor family 8 subfamily B member 12Bprovided by MGI
    Primary source
    MGI:MGI:3030709
    See related
    Ensembl:ENSMUSG00000058628 AllianceGenome:MGI:3030709
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Olfr875; MOR161-4
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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    Genomic context

    See Or8b12b in Genome Data Viewer
    Location:
    9 A4; 9 20.8 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (37683933..37684936)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (37772637..37773640)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 8 subfamily A member 1 Neighboring gene STARR-seq mESC enhancer starr_23817 Neighboring gene olfactory receptor family 8 subfamily B member 12 Neighboring gene STARR-seq mESC enhancer starr_23819 Neighboring gene olfactory receptor family 8 subfamily B member 12C Neighboring gene predicted gene, 24764

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables odorant binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    involved_in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    PubMed 

    General protein information

    Preferred Names
    olfactory receptor 875
    Names
    GA_x6K02T2PVTD-31458511-31459443
    olfactory receptor MOR161-4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146749.2NP_666960.2  olfactory receptor 875

      See identical proteins and their annotated locations for NP_666960.2

      Status: VALIDATED

      Source sequence(s)
      CT030124
      Consensus CDS
      CCDS22987.1
      UniProtKB/TrEMBL
      Q7TRE5, Q8VG17
      Related
      ENSMUSP00000079467.4, ENSMUST00000080634.4
      Conserved Domains (2) summary
      pfam00001
      Location:40289
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:30304
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      37683933..37684936
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)