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    Zpld2 zona pellucida like domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 665186, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zpld2provided by MGI
    Official Full Name
    zona pellucida like domain containing 2provided by MGI
    Primary source
    MGI:MGI:3702974
    See related
    Ensembl:ENSMUSG00000073747 AllianceGenome:MGI:3702974
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm7534; EG665186
    Summary
    Predicted to be involved in neutrophil migration. Predicted to be active in apical plasma membrane; cell surface; and extracellular space. Orthologous to human ZPLD2P (zona pellucida like domain containing 2, pseudogene). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See Zpld2 in Genome Data Viewer
    Location:
    4 D2.3; 4 66.5 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (133918115..133930315, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (134190804..134203004, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene SH3 domain binding glutamic acid-rich protein-like 3 Neighboring gene centrosomal protein 85 Neighboring gene STARR-positive B cell enhancer mm9_chr4:133715471-133715771 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:133742713-133742822 Neighboring gene STARR-positive B cell enhancer ABC_E843 Neighboring gene cation channel, sperm associated 4 Neighboring gene connector enhancer of kinase suppressor of Ras 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in neutrophil migration IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in apical plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080712.1NP_001074181.1  uromodulin-like

      See identical proteins and their annotated locations for NP_001074181.1

      Status: PROVISIONAL

      Source sequence(s)
      AK138880
      Consensus CDS
      CCDS38911.1
      UniProtKB/TrEMBL
      Q3UU21
      Related
      ENSMUSP00000095461.3, ENSMUST00000097849.3
      Conserved Domains (2) summary
      smart00241
      Location:368616
      ZP; Zona pellucida (ZP) domain
      pfam00100
      Location:497616
      Zona_pellucida; Zona pellucida-like domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      133918115..133930315 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)