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    Ranbp9 RAN binding protein 9 [ Mus musculus (house mouse) ]

    Gene ID: 56705, updated on 3-Dec-2024

    Summary

    Official Symbol
    Ranbp9provided by MGI
    Official Full Name
    RAN binding protein 9provided by MGI
    Primary source
    MGI:MGI:1928741
    See related
    Ensembl:ENSMUSG00000038546 AllianceGenome:MGI:1928741
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ibap1; IBAP-1; RanBPM
    Summary
    Predicted to enable small GTPase binding activity. Predicted to be involved in cytoskeleton organization and negative regulation of ERK1 and ERK2 cascade. Located in cytoplasm. Is expressed in cerebral cortex intermediate zone; cerebral cortex subventricular zone; cerebral cortex ventricular layer; and palatal shelf. Orthologous to human RANBP9 (RAN binding protein 9). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 40.0), adrenal adult (RPKM 14.1) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Ranbp9 in Genome Data Viewer
    Location:
    13 A4; 13 21.6 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (43556151..43634949, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (43402673..43481283, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53796 Neighboring gene sirtuin 5 Neighboring gene nucleolar protein 7 Neighboring gene predicted gene, 26064 Neighboring gene STARR-seq mESC enhancer starr_34338 Neighboring gene predicted gene, 32878 Neighboring gene non-histone chromosomal protein HMG-17 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Gene trapped (1) 
    • Targeted (4)  1 citation

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables small GTPase binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of ERK1 and ERK2 cascade ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of positive regulation of amyloid precursor protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    NOT located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ran-binding protein 9
    Names
    B cell antigen receptor Ig beta associated protein 1
    ran-binding protein M

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001404648.1NP_001391577.1  ran-binding protein 9 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC132121
      UniProtKB/Swiss-Prot
      P69566, P84500, Q3V136
      Related
      ENSMUSP00000152620.2, ENSMUST00000222651.2
    2. NM_019930.3NP_064314.2  ran-binding protein 9 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC132121
      Consensus CDS
      CCDS49252.1
      UniProtKB/Swiss-Prot
      P69566, P84500, Q3V136
      UniProtKB/TrEMBL
      E9Q5D6
      Related
      ENSMUSP00000130636.2, ENSMUST00000144326.4
      Conserved Domains (5) summary
      smart00667
      Location:346379
      LisH; Lissencephaly type-1-like homology motif
      smart00668
      Location:385441
      CTLH; C-terminal to LisH motif
      smart00757
      Location:597698
      CRA; CT11-RanBPM
      pfam10607
      Location:385439
      CLTH; CTLH/CRA C-terminal to LisH motif domain
      cd12909
      Location:171313
      SPRY_RanBP9_10; SPRY domain in Ran binding proteins 9 and 10

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      43556151..43634949 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_001780794.3 RNA Sequence