U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) [ Mus musculus (house mouse) ]

    Gene ID: 14812, updated on 9-Dec-2024

    Summary

    Official Symbol
    Grin2bprovided by MGI
    Official Full Name
    glutamate receptor, ionotropic, NMDA2B (epsilon 2)provided by MGI
    Primary source
    MGI:MGI:95821
    See related
    Ensembl:ENSMUSG00000030209 AllianceGenome:MGI:95821
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NR2B; GluN2B; Nmdar2b; GluRepsilon2
    Summary
    Enables NMDA glutamate receptor activity and calcium channel activity. Involved in negative regulation of dendritic spine maintenance. Acts upstream of or within several processes, including behavioral fear response; detection of mechanical stimulus involved in sensory perception of pain; and learning or memory. Located in several cellular components, including cytoplasmic vesicle; lysosome; and synaptic membrane. Part of NMDA selective glutamate receptor complex. Is active in glutamatergic synapse and postsynaptic density membrane. Is expressed in several structures, including adipose tissue; central nervous system; eye; genitourinary system; and gut. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; autosomal dominant intellectual developmental disorder 6; developmental and epileptic encephalopathy 27; neurodegenerative disease (multiple); and nicotine dependence. Orthologous to human GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in cortex adult (RPKM 5.7), frontal lobe adult (RPKM 5.7) and 5 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Grin2b in Genome Data Viewer
    Location:
    6 G1; 6 66.38 cM
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (135690219..136150658, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (135713221..136173615, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930425L21 gene Neighboring gene STARR-seq mESC enhancer starr_17574 Neighboring gene predicted gene, 38911 Neighboring gene STARR-seq mESC enhancer starr_17582 Neighboring gene predicted gene 14329 Neighboring gene predicted gene 14330 Neighboring gene STARR-seq mESC enhancer starr_17584 Neighboring gene predicted gene, 26653 Neighboring gene STARR-seq mESC enhancer starr_17586 Neighboring gene zinc finger protein 707 pseudogene Neighboring gene predicted gene, 26105

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables D2 dopamine receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables NMDA glutamate receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables NMDA glutamate receptor activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    enables NMDA glutamate receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables NMDA glutamate receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables NMDA glutamate receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables beta-catenin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables calcium channel activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables cell adhesion molecule binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables extracellularly glutamate-gated ion channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables glutamate binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables glutamate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables glutamate receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables glutamate-gated calcium ion channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables glutamate-gated calcium ion channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables glutamate-gated receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables glycine binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables heterocyclic compound binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables interleukin-1 receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ionotropic glutamate receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential ISO
    Inferred from Sequence Orthology
    more info
     
    enables monoatomic cation channel activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    enables neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein tyrosine kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables scaffold protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables signaling receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables small molecule binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential ISO
    Inferred from Sequence Orthology
    more info
     
    enables zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables zinc ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in NMDA selective glutamate receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in action potential ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in associative learning ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within behavioral fear response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in behavioral fear response ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within behavioral response to pain IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in calcium ion transmembrane import into cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in calcium ion transmembrane import into cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within calcium ion transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in calcium-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within chemical synaptic transmission IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within detection of mechanical stimulus involved in sensory perception of pain IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within embryo development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in excitatory postsynaptic potential IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within excitatory postsynaptic potential IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within excitatory postsynaptic potential IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within fear response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within in utero embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in intracellular calcium ion homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ionotropic glutamate receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ionotropic glutamate receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within learning IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within learning IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in learning or memory ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in learning or memory TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in long-term synaptic potentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within long-term synaptic potentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within long-term synaptic potentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within memory IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within memory IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in memory ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in monoatomic cation transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within monoatomic cation transport IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in negative regulation of dendritic spine maintenance IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of excitatory postsynaptic potential ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of excitatory postsynaptic potential ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of glutamate secretion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of inhibitory postsynaptic potential ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of synaptic transmission ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of synaptic transmission, glutamatergic ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of synaptic transmission, glutamatergic ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein heterotetramerization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein heterotetramerization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in receptor clustering ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of ARF protein signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of MAPK cascade ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of cAMP/PKA signal transduction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of long-term neuronal synaptic plasticity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of monoatomic cation transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of neuronal synaptic plasticity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in regulation of neuronal synaptic plasticity TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in regulation of postsynaptic cytosolic calcium ion concentration ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of postsynaptic membrane potential IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within regulation of synaptic plasticity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of synaptic plasticity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within response to ethanol IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in response to ethanol ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to hypoxia ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in rhythmic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sensitization ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within sensory organ development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within startle response IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within startle response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within suckling behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in synaptic transmission, glutamatergic IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of NMDA selective glutamate receptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of NMDA selective glutamate receptor complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    part_of NMDA selective glutamate receptor complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of NMDA selective glutamate receptor complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in Z disc ISO
    Inferred from Sequence Orthology
    more info
     
    located_in apical dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell surface IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in dendrite IEA
    Inferred from Electronic Annotation
    more info
     
    located_in dendritic branch ISO
    Inferred from Sequence Orthology
    more info
     
    located_in dendritic spine ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum membrane TAS
    Traceable Author Statement
    more info
     
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in hippocampal mossy fiber to CA3 synapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in late endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in lysosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in neuron projection IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in neuron projection ISO
    Inferred from Sequence Orthology
    more info
     
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in parallel fiber to Purkinje cell synapse ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     
    located_in postsynapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in postsynaptic density IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in postsynaptic density IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in postsynaptic density membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in postsynaptic density membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in postsynaptic density membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in postsynaptic density, intracellular component ISO
    Inferred from Sequence Orthology
    more info
     
    located_in postsynaptic membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in postsynaptic membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in presynaptic active zone membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in presynaptic membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in presynaptic membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in presynaptic membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in synapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in synaptic cleft ISO
    Inferred from Sequence Orthology
    more info
     
    located_in synaptic membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in synaptic vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in terminal bouton ISO
    Inferred from Sequence Orthology
    more info
     
    located_in transport vesicle membrane TAS
    Traceable Author Statement
    more info
     

    General protein information

    Preferred Names
    glutamate receptor ionotropic, NMDA 2B
    Names
    N-methyl D-aspartate receptor subtype 2B
    glutamate [NMDA] receptor subunit epsilon-2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001363750.1NP_001350679.1  glutamate receptor ionotropic, NMDA 2B precursor

      Status: VALIDATED

      Source sequence(s)
      AC124500, AC124590, AC132119, AC161364
      Consensus CDS
      CCDS20648.1
      UniProtKB/Swiss-Prot
      Q01097, Q9DCB2
      UniProtKB/TrEMBL
      G3X9V4
      Conserved Domains (3) summary
      cd13718
      Location:403803
      PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06378
      Location:33388
      PBP1_iGluR_NMDA_NR2; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
      pfam10565
      Location:8401482
      NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus
    2. NM_008171.4NP_032197.3  glutamate receptor ionotropic, NMDA 2B precursor

      Status: VALIDATED

      Source sequence(s)
      AC124500, AC124590, AC132119, AC161364
      Consensus CDS
      CCDS20648.1
      UniProtKB/Swiss-Prot
      Q01097, Q9DCB2
      UniProtKB/TrEMBL
      G3X9V4
      Related
      ENSMUSP00000107536.2, ENSMUST00000111905.8
      Conserved Domains (3) summary
      cd13718
      Location:403803
      PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06378
      Location:33388
      PBP1_iGluR_NMDA_NR2; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
      pfam10565
      Location:8401482
      NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      135690219..136150658 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011241221.4XP_011239523.1  glutamate receptor ionotropic, NMDA 2B isoform X1

      UniProtKB/Swiss-Prot
      Q01097, Q9DCB2
      UniProtKB/TrEMBL
      G3X9V4
      Conserved Domains (3) summary
      cd13718
      Location:403803
      PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06378
      Location:33388
      PBP1_iGluR_NMDA_NR2; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
      pfam10565
      Location:8401482
      NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus
    2. XM_006505575.5XP_006505638.1  glutamate receptor ionotropic, NMDA 2B isoform X1

      UniProtKB/Swiss-Prot
      Q01097, Q9DCB2
      UniProtKB/TrEMBL
      G3X9V4
      Conserved Domains (3) summary
      cd13718
      Location:403803
      PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06378
      Location:33388
      PBP1_iGluR_NMDA_NR2; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
      pfam10565
      Location:8401482
      NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus
    3. XM_006505574.5XP_006505637.1  glutamate receptor ionotropic, NMDA 2B isoform X1

      UniProtKB/Swiss-Prot
      Q01097, Q9DCB2
      UniProtKB/TrEMBL
      G3X9V4
      Conserved Domains (3) summary
      cd13718
      Location:403803
      PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06378
      Location:33388
      PBP1_iGluR_NMDA_NR2; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
      pfam10565
      Location:8401482
      NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus
    4. XM_006505573.5XP_006505636.1  glutamate receptor ionotropic, NMDA 2B isoform X1

      UniProtKB/Swiss-Prot
      Q01097, Q9DCB2
      UniProtKB/TrEMBL
      G3X9V4
      Conserved Domains (3) summary
      cd13718
      Location:403803
      PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06378
      Location:33388
      PBP1_iGluR_NMDA_NR2; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
      pfam10565
      Location:8401482
      NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus
    5. XM_036165858.1XP_036021751.1  glutamate receptor ionotropic, NMDA 2B isoform X1

      UniProtKB/Swiss-Prot
      Q01097, Q9DCB2
      UniProtKB/TrEMBL
      G3X9V4
      Conserved Domains (3) summary
      cd13718
      Location:403803
      PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06378
      Location:33388
      PBP1_iGluR_NMDA_NR2; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
      pfam10565
      Location:8401482
      NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus