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    Ceacam11 CEA cell adhesion molecule 11 [ Mus musculus (house mouse) ]

    Gene ID: 66996, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Ceacam11provided by MGI
    Official Full Name
    CEA cell adhesion molecule 11provided by MGI
    Primary source
    MGI:MGI:1914246
    See related
    Ensembl:ENSMUSG00000030368 AllianceGenome:MGI:1914246
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1600015D01Rik
    Summary
    Predicted to be involved in T cell activation and immune response. Predicted to be located in apical plasma membrane and cytosol. Predicted to be active in external side of plasma membrane. Is expressed in head; placenta; and spongiotrophoblast. Orthologous to human CEACAM7 (CEA cell adhesion molecule 7). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward placenta adult (RPKM 401.2) See more
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    Genomic context

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    See Ceacam11 in Genome Data Viewer
    Location:
    7 A2; 7 9.15 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (17706092..17712481)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (17972167..17978556)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene CEA cell adhesion molecule 14 Neighboring gene CEA cell adhesion moleculen23 Neighboring gene STARR-seq mESC enhancer starr_18157 Neighboring gene STARR-seq mESC enhancer starr_18158 Neighboring gene STARR-seq mESC enhancer starr_18159 Neighboring gene STARR-seq mESC enhancer starr_18160 Neighboring gene STARR-seq mESC enhancer starr_18161 Neighboring gene MHC I like leukocyte 2 pseudogene Neighboring gene CEA cell adhesion molecule 13

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A carcinoembryonic antigen family cDNA from mouse placenta encoding a protein with a rare domain composition. Kataoka K, et al. Placenta, 2000 Sep. PMID 10985962
    2. Peg3 mutational effects on reproduction and placenta-specific gene families. Kim J, et al. PLoS One, 2013. PMID 24391757, Free PMC Article
    3. Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network. Shalom-Barak T, et al. Dev Biol, 2012 Dec 1. PMID 22967998, Free PMC Article
    4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC117645

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in T cell activation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    CEA-related cell adhesion molecule 11
    Names
    Ceacam11-C1
    Ceacam11-C3
    Ceacam11-C4
    carcinoembryonic antigen related protein
    carcinoembryonic antigen-related cell adhesion molecule 11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023289.2 → NP_075778.2  CEA-related cell adhesion molecule 11 precursor

      See identical proteins and their annotated locations for NP_075778.2

      Status: VALIDATED

      Source sequence(s)
      AK004142, BC099452
      Consensus CDS
      CCDS20865.1
      UniProtKB/TrEMBL
      Q4KL40, Q9D0Z8, Q9ES69
      Related
      ENSMUSP00000092393.3, ENSMUST00000094799.3
      Conserved Domains (1) summary
      cd05774
      Location:36 → 140
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      17706092..17712481
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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