U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Zswim7 zinc finger, SWIM-type containing 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287388, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Zswim7provided by RGD
    Official Full Name
    zinc finger, SWIM-type containing 7provided by RGD
    Primary source
    RGD:1310324
    See related
    AllianceGenome:RGD:1310324
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310324
    Summary
    Predicted to enable zinc ion binding activity. Predicted to be involved in double-strand break repair via homologous recombination and protein stabilization. Predicted to be part of Shu complex. Human ortholog(s) of this gene implicated in 46 XX gonadal dysgenesis and spermatogenic failure 71. Orthologous to human ZSWIM7 (zinc finger SWIM-type containing 7). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 73.7), Testes (RPKM 59.0) and 9 other tissues See more
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Zswim7 in Genome Data Viewer
    Location:
    10q23
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (47456843..47469084, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (46953311..46969800, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (48587117..48599208, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene sperm antigen with calponin homology and coiled-coil domains 1 Neighboring gene selenoprotein W, pseudogene 1 Neighboring gene adenosine A2B receptor Neighboring gene tetratricopeptide repeat domain 19 Neighboring gene nuclear receptor co-repressor 1 Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class L Neighboring gene transmembrane p24 trafficking protein 4, pseudogene 1 Neighboring gene centromere protein V

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. hSWS1·SWSAP1 is an evolutionarily conserved complex required for efficient homologous recombination repair. Liu T, et al. J Biol Chem, 2011 Dec 2. PMID 21965664, Free PMC Article
    2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in double-strand break repair via homologous recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in double-strand break repair via homologous recombination ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein stabilization ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of Shu complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Shu complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    zinc finger SWIM domain-containing protein 7

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163492.1 → NP_001156964.1  zinc finger SWIM domain-containing protein 7

      See identical proteins and their annotated locations for NP_001156964.1

      Status: VALIDATED

      Source sequence(s)
      BF522197, BQ209551
      UniProtKB/TrEMBL
      A6HF95

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      47456843..47469084 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063268625.1 → XP_063124695.1  zinc finger SWIM domain-containing protein 7 isoform X3

    2. XM_039085421.2 → XP_038941349.1  zinc finger SWIM domain-containing protein 7 isoform X2

    3. XM_039085419.2 → XP_038941347.1  zinc finger SWIM domain-containing protein 7 isoform X1

    RNA

    1. XR_010055149.1 RNA Sequence

    2. XR_010055148.1 RNA Sequence

    3. XR_010055147.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.