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    PF3D7_1454700 6-phosphogluconate dehydrogenase, decarboxylating [ Plasmodium falciparum 3D7 ]

    Gene ID: 812102, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_1454700
    Gene description
    6-phosphogluconate dehydrogenase, decarboxylating
    Locus tag
    PF3D7_1454700
    See related
    PlasmoDB:PF3D7_1454700; VEuPathDB:PF3D7_1454700
    Gene type
    protein coding
    RNA name
    6-phosphogluconate dehydrogenase, decarboxylating
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_1454700 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    1
    Sequence:
    Chromosome: 14; NC_037283.1 (2241433..2242839)

    Chromosome 14 - NC_037283.1Genomic Context describing neighboring genes Neighboring gene iron sulfur cluster assembly protein, putative Neighboring gene mitochondrial ribosomal protein S11 precursor, putative Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene conserved protein, unknown function

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037283.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of Plasmodium falciparum 6-Phosphogluconate Dehydrogenase as an Antimalarial Drug Target. Haeussler K, et al. J Mol Biol, 2018 Oct 19. PMID 30098336
    2. Proteome mapping of Plasmodium: identification of the P. yoelii remodellome. Siau A, et al. Sci Rep, 2016 Aug 9. PMID 27503796, Free PMC Article
    3. Identification of Plasmodium falciparum nuclear proteins by mass spectrometry and proposed protein annotation. Briquet S, et al. PLoS One, 2018. PMID 30379851, Free PMC Article
    4. Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum. Oehring SC, et al. Genome Biol, 2012 Nov 26. PMID 23181666, Free PMC Article
    5. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables phosphogluconate dehydrogenase (decarboxylating) activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within pentose-phosphate shunt IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to xenobiotic stimulus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in intracellular anatomical structure ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    6-phosphogluconate dehydrogenase, decarboxylating
    XP_001348694.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037283.1 Reference assembly

      Range
      2241433..2242839
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001348658.3 → XP_001348694.1  6-phosphogluconate dehydrogenase, decarboxylating [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001348694.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A024UYT7, A0A024VZM0, A0A024WH43, A0A024X140, A0A0L1IFL4, A0A0L7K6H8, A0A0L7M897, Q8IKT2, W4I9K0, W4IW03, W7F3T4, W7FMI8, W7JG11, W7JNT3
      Conserved Domains (1) summary
      PTZ00142
      Location:1 → 468
      PTZ00142; 6-phosphogluconate dehydrogenase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    6FQX_A.1
    6FQX_B.1
    6FQX_C.1
    6FQX_D.1
    6FQX_E.1
    6FQX_F.1
    6FQX_G.1
    6FQX_H.1
    6FQY_A.1
    6FQY_B.1
    6FQZ_A.1
    6FQZ_B.1

    Gene LinkOut

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