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    PF3D7_0802800 serine/threonine protein phosphatase 2B catalytic subunit A [ Plasmodium falciparum 3D7 ]

    Gene ID: 2655328, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_0802800
    Gene description
    serine/threonine protein phosphatase 2B catalytic subunit A
    Locus tag
    PF3D7_0802800
    See related
    PlasmoDB:PF3D7_0802800; VEuPathDB:PF3D7_0802800
    Gene type
    protein coding
    RNA name
    serine/threonine protein phosphatase 2B catalytic subunit A
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_0802800 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    2
    Sequence:
    Chromosome: 8; NC_004329.3 (191976..194103)

    Chromosome 8 - NC_004329.3Genomic Context describing neighboring genes Neighboring gene adenylyl cyclase beta Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene peptidyl-prolyl cis-trans isomerase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_004329.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Parasite Calcineurin Regulates Host Cell Recognition and Attachment by Apicomplexans. Paul AS, et al. Cell Host Microbe, 2015 Jul 8. PMID 26118996, Free PMC Article
    2. The FK506-binding protein of the malaria parasite, Plasmodium falciparum, is a FK506-sensitive chaperone with FK506-independent calcineurin-inhibitory activity. Kumar R, et al. Mol Biochem Parasitol, 2005 Jun. PMID 15850699
    3. Post-translational generation of constitutively active cores from larger phosphatases in the malaria parasite, Plasmodium falciparum: implications for proteomics. Kumar R, et al. BMC Mol Biol, 2004 Jul 1. PMID 15230980, Free PMC Article
    4. A protein interaction network of the malaria parasite Plasmodium falciparum. LaCount DJ, et al. Nature, 2005 Nov 3. PMID 16267556

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Process Evidence Code Pubs
    acts_upstream_of_or_within protein dephosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of calcineurin complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine protein phosphatase 2B catalytic subunit A
    XP_001349486.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004329.3 Reference assembly

      Range
      191976..194103
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001349450.1 → XP_001349486.1  serine/threonine protein phosphatase 2B catalytic subunit A [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001349486.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A0L7KBS7, Q8IAM8, W7K6H6
      Conserved Domains (1) summary
      cd07416
      Location:38 → 344
      MPP_PP2B; PP2B, metallophosphatase domain
    Nucleotide Protein
    Heading Accession and Version

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