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    Idnk idnK gluconokinase homolog (E. coli) [ Mus musculus (house mouse) ]

    Gene ID: 75731, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Idnkprovided by MGI
    Official Full Name
    idnK gluconokinase homolog (E. coli)provided by MGI
    Primary source
    MGI:MGI:1922981
    See related
    Ensembl:ENSMUSG00000050002 AllianceGenome:MGI:1922981
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    5133401N09Rik
    Summary
    Predicted to enable gluconokinase activity. Predicted to be involved in D-gluconate catabolic process. Is expressed in nervous system and thymus primordium. Orthologous to human IDNK (IDNK gluconokinase). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in large intestine adult (RPKM 7.5), CNS E11.5 (RPKM 7.1) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Idnk in Genome Data Viewer
    Location:
    13 B1; 13 30.95 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (58305076..58315358)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (58157649..58164693)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40964 Neighboring gene RIKEN cDNA 1700066J03 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:58258990-58259099 Neighboring gene STARR-positive B cell enhancer ABC_E10797 Neighboring gene ubiquilin 1 Neighboring gene 60S ribosomal protein L17 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables gluconokinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables gluconokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in D-gluconate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in D-gluconate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    probable gluconokinase
    Names
    gluconate kinase
    NP_001041525.1
    NP_932121.2
    XP_036014105.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001048060.2 → NP_001041525.1  probable gluconokinase isoform b

      See identical proteins and their annotated locations for NP_001041525.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate exon that causes a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (b) has a distinct and shorter C-terminus, compared to isoform a.
      Source sequence(s)
      AC163038, AK032811
      Consensus CDS
      CCDS36683.1
      UniProtKB/TrEMBL
      D3Z4J6
      Related
      ENSMUSP00000105494.3, ENSMUST00000109868.4
      Conserved Domains (1) summary
      cl17190
      Location:6 → 55
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    2. NM_198004.3 → NP_932121.2  probable gluconokinase isoform a

      See identical proteins and their annotated locations for NP_932121.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
      Source sequence(s)
      AC163038, AK032811, AK045763, CX206109
      Consensus CDS
      CCDS36682.1
      UniProtKB/Swiss-Prot
      Q8R0J8
      Related
      ENSMUSP00000060218.8, ENSMUST00000051490.15
      Conserved Domains (2) summary
      COG0703
      Location:1 → 184
      AroK; Shikimate kinase [Amino acid transport and metabolism]
      COG3265
      Location:10 → 184
      GntK; Gluconate kinase [Carbohydrate transport and metabolism]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      58305076..58315358
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036158212.1 → XP_036014105.1  probable gluconokinase isoform X1

      UniProtKB/TrEMBL
      D3Z4J6
      Conserved Domains (1) summary
      cl17190
      Location:6 → 55
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8R0J8.2 GenPept UniProtKB/Swiss-Prot:Q8R0J8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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