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    SLC19A1 solute carrier family 19 member 1 [ Homo sapiens (human) ]

    Gene ID: 6573, updated on 10-Dec-2024

    Summary

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    Official Symbol
    SLC19A1provided by HGNC
    Official Full Name
    solute carrier family 19 member 1provided by HGNC
    Primary source
    HGNC:HGNC:10937
    See related
    Ensembl:ENSG00000173638 MIM:600424; AllianceGenome:HGNC:10937
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    RFC; CHMD; FOLT; IFC1; REFC; RFC1; hRFC; IFC-1; MEGAF; RFT-1; IMD114; hSLC19A1
    Summary
    The membrane protein encoded by this gene is a transporter of folate and is involved in the regulation of intracellular concentrations of folate. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
    Annotation information
    Note: RFC1 (GeneID: 5981) and SLC19A1 (GeneID: 6573) share the RFC1 symbol/alias in common. RFC1 is the official symbol for the gene name 'replication factor C subunit 1' and is an alias for 'reduced folate carrier 1' on the 'solute carrier family 19 member 1' gene. [18 May 2018]
    Expression
    Ubiquitous expression in liver (RPKM 10.8), placenta (RPKM 8.5) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See SLC19A1 in Genome Data Viewer
    Location:
    21q22.3
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (45502517..45563025, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (43870718..43932046, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (46932461..46982939, complement)

    Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124905042 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46858777-46859506 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46859507-46860236 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46860237-46860966 Neighboring gene collagen type XVIII alpha 1 chain Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46862147-46862656 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46870853-46871354 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46871355-46871854 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46874827-46875383 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46885176-46885740 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46885741-46886304 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18590 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46894762-46895262 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46908672-46909202 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46912122-46912622 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46934825-46935332 Neighboring gene microRNA 6815 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46935840-46936346 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18591 Neighboring gene Sharpr-MPRA regulatory region 1559 Neighboring gene ReSE screen-validated silencer GRCh37_chr21:46948644-46948814 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46954106-46954980 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13402 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13403 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46962482-46962994 Neighboring gene ReSE screen-validated silencer GRCh37_chr21:46970045-46970201 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13405 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13406 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46975660-46976554 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46980259-46980968 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46998853-46999354 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:47001008-47001944 Neighboring gene uncharacterized LOC107985485 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:47009554-47010054 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13407 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13408 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13409 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:47015623-47016124 Neighboring gene Sharpr-MPRA regulatory region 7423 Neighboring gene MPRA-validated peak4424 silencer Neighboring gene MPRA-validated peak4426 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:47031725-47032226 Neighboring gene long intergenic non-protein coding RNA 1694 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr21:47053121-47054320 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18594 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18595 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:47057095-47057612 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13410 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13411 Neighboring gene poly(rC) binding protein 3 Neighboring gene H3K27ac hESC enhancer GRCh37_chr21:47204393-47205264 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:47236921-47237422 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:47237423-47237922 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:47241669-47242354 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:47244540-47245132 Neighboring gene MPRA-validated peak4427 silencer Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:47255439-47255946 Neighboring gene PCBP3 antisense RNA 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. RFC1 and non-syndromic cleft lip with or without cleft palate: an association based study in Italy. Girardi A, et al. J Craniomaxillofac Surg, 2014 Oct. PMID 24942095
    2. [Epidemiological study on reduced folate carrier gene(RFC1 A80G) polymorphism and other risk factors of neural tube defects]. Pei LJ, et al. Beijing Da Xue Xue Bao Yi Xue Ban, 2005 Aug 18. PMID 16086047
    3. Polymorphism G80A in the reduced folate carrier gene and its relationship to survival and risk of relapse in acute lymphoblastic leukemia. Leyva-Vázquez MA, et al. J Investig Med, 2012 Oct. PMID 22914600
    4. Reduced folate carrier A80G polymorphism and susceptibility to neural tube defects: a meta-analysis. Wang HG, et al. Gene, 2012 Dec 1. PMID 22975209
    5. Genetic variation of infant reduced folate carrier (A80G) and risk of orofacial defects and congenital heart defects in China. Pei L, et al. Ann Epidemiol, 2006 May. PMID 16019224

    See all (313) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC.
      Title: Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC.
    2. Gender-specific association of SLC19A1 and MTHFR genetic polymorphism with oxidative stress biomarkers and plasma folate levels in older adults.
      Title: Gender-specific association of SLC19A1 and MTHFR genetic polymorphism with oxidative stress biomarkers and plasma folate levels in older adults.
    3. Correlation between methylation level of the SLC19A1 promoter region and methotrexate metabolism in adult acute lymphoblastic leukemia.
      Title: Correlation between methylation level of the SLC19A1 promoter region and methotrexate metabolism in adult acute lymphoblastic leukemia.
    4. Genetic aetiology of Down syndrome birth: novel variants of maternal DNMT3B and RFC1 genes increase risk of meiosis II nondisjunction in the oocyte.
      Title: Genetic aetiology of Down syndrome birth: novel variants of maternal DNMT3B and RFC1 genes increase risk of meiosis II nondisjunction in the oocyte.
    5. Recognition of cyclic dinucleotides and folates by human SLC19A1.
      Title: Recognition of cyclic dinucleotides and folates by human SLC19A1.
    6. Methotrexate recognition by the human reduced folate carrier SLC19A1.
      Title: Methotrexate recognition by the human reduced folate carrier SLC19A1.
    7. SLC19A1 Genetic Variation Leads to Altered Thiamine Diphosphate Transport: Implications for the Risk of Developing Wernicke-Korsakoff's Syndrome.
      Title: SLC19A1 Genetic Variation Leads to Altered Thiamine Diphosphate Transport: Implications for the Risk of Developing Wernicke-Korsakoff's Syndrome.
    8. Hypoxia-Immune-Related Gene SLC19A1 Serves as a Potential Biomarker for Prognosis in Multiple Myeloma.
      Title: Hypoxia-Immune-Related Gene SLC19A1 Serves as a Potential Biomarker for Prognosis in Multiple Myeloma.
    9. The transcriptome profile of human trisomy 21 blood cells.
      Title: The transcriptome profile of human trisomy 21 blood cells.
    10. Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability.
      Title: Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability.
    Submit: New GeneRIF Correction See all GeneRIFs (176)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Associated conditions

    Description Tests
    Immunodeficiency 114, folate-responsive
    MedGen: C5882719 OMIM: 620603 GeneReviews: Not available
    		not available
    Megaloblastic anemia, folate-responsive
    MedGen: C2749656 OMIM: 601775 GeneReviews: Not available
    		Compare labs

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    HIV-1 interactions

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    Replication interactions

    Interaction Pubs
    HIV-1 infection (VSV-G pseudotyped) of CEMT4 T cells downregulates plasma membrane expression of SLC19A1 PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables 2',3'-cyclic GMP-AMP binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables antiporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables cyclic-GMP-AMP transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables folate:monoatomic anion antiporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables folate:monoatomic anion antiporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables folate:monoatomic anion antiporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables folic acid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables folic acid transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables folic acid transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables folic acid transmembrane transporter activity TAS
    Traceable Author Statement
    more info
    		  
    enables methotrexate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables organic anion transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables xenobiotic transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in cyclic-GMP-AMP transmembrane import across plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in female pregnancy IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in folate import across plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in folate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in folate transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in folic acid metabolic process TAS
    Traceable Author Statement
    more info
    		  
    involved_in folic acid transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in folic acid transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in methotrexate transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in monoatomic anion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in organic anion transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of cGAS/STING signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transport across blood-brain barrier NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in transport across blood-brain barrier TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in xenobiotic transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in apical plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in apical plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in basolateral plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in basolateral plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in basolateral plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in brush border membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
    		  

    General protein information

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    Preferred Names
    reduced folate transporter
    Names
    cyclic dinucleotide:anion antiporter SLC19A1
    folate transporter 1
    folate:anion antiporter SLC19A1
    intestinal folate carrier 1
    placental folate transporter
    reduced folate carrier 1
    reduced folate carrier protein
    reduced folate transporter 1
    solute carrier family 19 (folate transporter), member 1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_028278.2 RefSeqGene

      Range
      25704..55579
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001205206.4 → NP_001192135.1  reduced folate transporter isoform 2

      Status: REVIEWED

      Source sequence(s)
      AK307623, AK313125, BC003068, BC023005, BX322561
      Consensus CDS
      CCDS56218.1
      UniProtKB/Swiss-Prot
      P41440
      Related
      ENSP00000369347.4, ENST00000380010.8
      Conserved Domains (1) summary
      TIGR00806
      Location:1 → 431
      rfc; RFC reduced folate carrier

    2. NM_001205207.3 → NP_001192136.1  reduced folate transporter isoform 3

      See identical proteins and their annotated locations for NP_001192136.1

      Status: REVIEWED

      Source sequence(s)
      AK303168, BC023005, BX322561, DC311922, U19720
      Consensus CDS
      CCDS56217.1
      UniProtKB/Swiss-Prot
      P41440
      Related
      ENSP00000441772.1, ENST00000485649.3
      Conserved Domains (1) summary
      TIGR00806
      Location:23 → 466
      rfc; RFC reduced folate carrier

    3. NM_001352510.2 → NP_001339439.1  reduced folate transporter isoform 4

      Status: REVIEWED

      Source sequence(s)
      BC023005, BX322561
      Conserved Domains (1) summary
      cl27502
      Location:1 → 388
      Folate_carrier; Reduced folate carrier

    4. NM_001352511.3 → NP_001339440.1  reduced folate transporter isoform 2

      Status: REVIEWED

      Source sequence(s)
      BC023005, BX322561
      Consensus CDS
      CCDS56218.1
      Related
      ENSP00000498221.1, ENST00000650808.1
      Conserved Domains (1) summary
      TIGR00806
      Location:1 → 431
      rfc; RFC reduced folate carrier

    5. NM_001352512.2 → NP_001339441.1  reduced folate transporter isoform 1

      Status: REVIEWED

      Source sequence(s)
      BC023005, BX322561
      Consensus CDS
      CCDS13725.1
      UniProtKB/Swiss-Prot
      B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8
      Conserved Domains (1) summary
      TIGR00806
      Location:1 → 506
      rfc; RFC reduced folate carrier

    6. NM_194255.4 → NP_919231.1  reduced folate transporter isoform 1

      See identical proteins and their annotated locations for NP_919231.1

      Status: REVIEWED

      Source sequence(s)
      AK307623, AK313125, BC023005, BX322561, U19720
      Consensus CDS
      CCDS13725.1
      UniProtKB/Swiss-Prot
      B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8
      Related
      ENSP00000308895.4, ENST00000311124.9
      Conserved Domains (1) summary
      TIGR00806
      Location:1 → 506
      rfc; RFC reduced folate carrier

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

      Range
      45502517..45563025 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047440963.1 → XP_047296919.1  reduced folate transporter isoform X11

    2. XM_047440964.1 → XP_047296920.1  reduced folate transporter isoform X11

    3. XM_047440957.1 → XP_047296913.1  reduced folate transporter isoform X5

    4. XM_047440960.1 → XP_047296916.1  reduced folate transporter isoform X8

    5. XM_047440955.1 → XP_047296911.1  reduced folate transporter isoform X3

    6. XM_047440965.1 → XP_047296921.1  reduced folate transporter isoform X12

    7. XM_047440962.1 → XP_047296918.1  reduced folate transporter isoform X10

    8. XM_047440961.1 → XP_047296917.1  reduced folate transporter isoform X9

    9. XM_011529700.3 → XP_011528002.1  reduced folate transporter isoform X6

      See identical proteins and their annotated locations for XP_011528002.1

      UniProtKB/Swiss-Prot
      B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8
      Conserved Domains (1) summary
      TIGR00806
      Location:1 → 506
      rfc; RFC reduced folate carrier

    10. XM_047440954.1 → XP_047296910.1  reduced folate transporter isoform X2

    11. XM_011529696.3 → XP_011527998.1  reduced folate transporter isoform X2

      See identical proteins and their annotated locations for XP_011527998.1

      Conserved Domains (1) summary
      TIGR00806
      Location:98 → 603
      rfc; RFC reduced folate carrier

    12. XM_017028443.2 → XP_016883932.2  reduced folate transporter isoform X6

      UniProtKB/Swiss-Prot
      B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8

    13. XM_011529702.3 → XP_011528004.1  reduced folate transporter isoform X6

      See identical proteins and their annotated locations for XP_011528004.1

      UniProtKB/Swiss-Prot
      B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8
      Conserved Domains (1) summary
      TIGR00806
      Location:1 → 506
      rfc; RFC reduced folate carrier

    14. XM_047440958.1 → XP_047296914.1  reduced folate transporter isoform X6

      UniProtKB/Swiss-Prot
      B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8

    15. XM_011529698.3 → XP_011528000.1  reduced folate transporter isoform X1

      See identical proteins and their annotated locations for XP_011528000.1

      Conserved Domains (1) summary
      TIGR00806
      Location:23 → 528
      rfc; RFC reduced folate carrier

    16. XM_011529703.3 → XP_011528005.1  reduced folate transporter isoform X6

      See identical proteins and their annotated locations for XP_011528005.1

      UniProtKB/Swiss-Prot
      B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8
      Conserved Domains (1) summary
      TIGR00806
      Location:1 → 506
      rfc; RFC reduced folate carrier

    17. XM_047440956.1 → XP_047296912.1  reduced folate transporter isoform X4

    18. XM_047440959.1 → XP_047296915.1  reduced folate transporter isoform X7

    19. XM_011529706.4 → XP_011528008.1  reduced folate transporter isoform X7

      Conserved Domains (1) summary
      TIGR00806
      Location:18 → 460
      rfc; RFC reduced folate carrier

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_025791815.1 Reference GRCh38.p14 PATCHES

      Range
      119752..180251 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054333325.1 → XP_054189300.1  reduced folate transporter isoform X11

    2. XM_054333326.1 → XP_054189301.1  reduced folate transporter isoform X11

    3. XM_054333315.1 → XP_054189290.1  reduced folate transporter isoform X5

    4. XM_054333313.1 → XP_054189288.1  reduced folate transporter isoform X3

    5. XM_054333321.1 → XP_054189296.1  reduced folate transporter isoform X8

    6. XM_054333327.1 → XP_054189302.1  reduced folate transporter isoform X12

    7. XM_054333324.1 → XP_054189299.1  reduced folate transporter isoform X10

    8. XM_054333322.1 → XP_054189297.1  reduced folate transporter isoform X9

    9. XM_054333323.1 → XP_054189298.1  reduced folate transporter isoform X6

      UniProtKB/Swiss-Prot
      B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8

    10. XM_054333310.1 → XP_054189285.1  reduced folate transporter isoform X2

    11. XM_054333311.1 → XP_054189286.1  reduced folate transporter isoform X2

    12. XM_054333312.1 → XP_054189287.1  reduced folate transporter isoform X2

    13. XM_054333316.1 → XP_054189291.1  reduced folate transporter isoform X6

      UniProtKB/Swiss-Prot
      B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8

    14. XM_054333318.1 → XP_054189293.1  reduced folate transporter isoform X6

      UniProtKB/Swiss-Prot
      B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8

    15. XM_054333309.1 → XP_054189284.1  reduced folate transporter isoform X1

    16. XM_054333317.1 → XP_054189292.1  reduced folate transporter isoform X6

      UniProtKB/Swiss-Prot
      B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8

    17. XM_054333314.1 → XP_054189289.1  reduced folate transporter isoform X4

    18. XM_054333320.1 → XP_054189295.1  reduced folate transporter isoform X7

    19. XM_054333319.1 → XP_054189294.1  reduced folate transporter isoform X7

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060945.1 Alternate T2T-CHM13v2.0

      Range
      43870718..43932046 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054324804.1 → XP_054180779.1  reduced folate transporter isoform X11

    2. XM_054324805.1 → XP_054180780.1  reduced folate transporter isoform X11

    3. XM_054324794.1 → XP_054180769.1  reduced folate transporter isoform X5

    4. XM_054324792.1 → XP_054180767.1  reduced folate transporter isoform X3

    5. XM_054324800.1 → XP_054180775.1  reduced folate transporter isoform X8

    6. XM_054324806.1 → XP_054180781.1  reduced folate transporter isoform X12

    7. XM_054324803.1 → XP_054180778.1  reduced folate transporter isoform X10

    8. XM_054324801.1 → XP_054180776.1  reduced folate transporter isoform X9

    9. XM_054324802.1 → XP_054180777.1  reduced folate transporter isoform X6

    10. XM_054324789.1 → XP_054180764.1  reduced folate transporter isoform X2

    11. XM_054324790.1 → XP_054180765.1  reduced folate transporter isoform X2

    12. XM_054324791.1 → XP_054180766.1  reduced folate transporter isoform X2

    13. XM_054324795.1 → XP_054180770.1  reduced folate transporter isoform X6

    14. XM_054324797.1 → XP_054180772.1  reduced folate transporter isoform X6

    15. XM_054324788.1 → XP_054180763.1  reduced folate transporter isoform X1

    16. XM_054324796.1 → XP_054180771.1  reduced folate transporter isoform X6

    17. XM_054324793.1 → XP_054180768.1  reduced folate transporter isoform X4

    18. XM_054324799.1 → XP_054180774.1  reduced folate transporter isoform X7

    19. XM_054324798.1 → XP_054180773.1  reduced folate transporter isoform X7

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_003056.2: Suppressed sequence

      Description
      NM_003056.2: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P41440.3 GenPept UniProtKB/Swiss-Prot:P41440

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