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    TAF10 Taf10p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851745, updated on 9-Dec-2024

    Summary

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    Official Symbol
    TAF10
    Official Full Name
    Taf10p
    Primary source
    SGD:S000002574
    Locus tag
    YDR167W
    See related
    AllianceGenome:SGD:S000002574; FungiDB:YDR167W; VEuPathDB:YDR167W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    TAF23; TAF25
    Summary
    Enables chromatin binding activity and molecular adaptor activity. Involved in RNA polymerase II preinitiation complex assembly and chromatin organization. Part of SAGA complex; SLIK (SAGA-like) complex; and transcription factor TFIID complex. Orthologous to human TAF10 (TATA-box binding protein associated factor 10). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See TAF10 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (789449..790069)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Trm82p Neighboring gene exocyst subunit SEC5 Neighboring gene Cdc37p Neighboring gene Stb3p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Improvement of oxidative stress tolerance in Saccharomyces cerevisiae through global transcription machinery engineering. Zhao H, et al. J Ind Microbiol Biotechnol, 2014 May. PMID 24633583
    2. Engineering yeast transcription machinery for improved ethanol tolerance and production. Alper H, et al. Science, 2006 Dec 8. PMID 17158319
    3. Activator-mediated recruitment of the RNA polymerase II machinery is the predominant mechanism for transcriptional activation in yeast. Keaveney M, et al. Mol Cell, 1998 May. PMID 9660975
    4. TAF25p, a non-histone-like subunit of TFIID and SAGA complexes, is essential for total mRNA gene transcription in vivo. Sanders SL, et al. J Biol Chem, 1999 Jul 2. PMID 10383379
    5. Validation of reference genes for quantitative expression analysis by real-time RT-PCR in Saccharomyces cerevisiae. Teste MA, et al. BMC Mol Biol, 2009 Oct 30. PMID 19874630, Free PMC Article

    See all (128) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    contributes_to RNA polymerase II general transcription initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables chromatin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables molecular adaptor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables promoter-specific chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA-templated transcription initiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in RNA polymerase II preinitiation complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in chromatin organization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transcription initiation at RNA polymerase II promoter IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of SAGA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of SAGA complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of SLIK (SAGA-like) complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription factor TFIID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIID complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Taf10p
    NP_010451.3
    • Subunit (145 kDa) of TFIID and SAGA complexes; involved in RNA polymerase II transcription initiation and in chromatin modification

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      789449..790069
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180474.3 → NP_010451.3  TPA: Taf10p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010451.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VSE7, Q12030
      UniProtKB/TrEMBL
      A6ZYC5, B3LGB7, B5VG62, C7GQF2, G2WAR5, N1P6Q6
      Conserved Domains (1) summary
      COG5162
      Location:1 → 206
      COG5162; Transcription initiation factor TFIID, subunit TAF10 (also component of histone acetyltransferase SAGA) [Transcription]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12030.1

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