Rpp25 ribonuclease P/MRP 25 subunit [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Rpp25provided by MGI
Official Full Name: ribonuclease P/MRP 25 subunitprovided by MGI
Primary source: MGI:MGI:2143151
See related: Ensembl:ENSMUSG00000062309 AllianceGenome:MGI:2143151
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in tRNA 5'-leader removal. Predicted to be located in centriolar satellite and nucleoplasm. Predicted to be part of multimeric ribonuclease P complex and ribonuclease MRP complex. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human RPP25 (ribonuclease P and MRP subunit p25). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human all
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Genomic context

Location:: 9 B; 9 31.05 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	9	NC_000075.7 (57411385..57412730)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	9	NC_000075.6 (57504102..57505447)

Chromosome 9 - NC_000075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

AI851155 (e-PCR)
- UniSTS:165636

Rpp25 (e-PCR), detects polymorphism
- UniSTS:507198

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables ribonuclease P RNA binding	ISO Inferred from Sequence Orthology more info
enables ribonuclease P RNA binding	ISS Inferred from Sequence or Structural Similarity more info
contributes_to ribonuclease P activity	ISO Inferred from Sequence Orthology more info
contributes_to ribonuclease P activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in rRNA processing	IEA Inferred from Electronic Annotation more info
involved_in tRNA 5'-leader removal	IBA Inferred from Biological aspect of Ancestor more info
involved_in tRNA 5'-leader removal	ISO Inferred from Sequence Orthology more info
involved_in tRNA 5'-leader removal	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in centriolar satellite	IEA Inferred from Electronic Annotation more info
located_in centriolar satellite	ISO Inferred from Sequence Orthology more info
part_of multimeric ribonuclease P complex	ISO Inferred from Sequence Orthology more info
part_of multimeric ribonuclease P complex	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
part_of ribonuclease MRP complex	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonuclease MRP complex	IEA Inferred from Electronic Annotation more info
part_of ribonuclease MRP complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: ribonuclease P protein subunit p25

Names: RNase P protein subunit p25; ribonuclease P 25 subunit; ribonuclease P 25kDa subunit

NP_598743.1

EC 3.1.26.5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.