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    Prss47 serine protease 47 [ Mus musculus (house mouse) ]

    Gene ID: 218304, updated on 9-Dec-2024

    Summary

    Official Symbol
    Prss47provided by MGI
    Official Full Name
    serine protease 47provided by MGI
    Primary source
    MGI:MGI:2685120
    See related
    Ensembl:ENSMUSG00000090658 AllianceGenome:MGI:2685120
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm274
    Summary
    Orthologous to human PRSS47P (serine protease 47, pseudogene). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 12.5) See more
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    Genomic context

    See Prss47 in Genome Data Viewer
    Location:
    13 B3; 13 34.21 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (65192427..65200685, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (65044613..65052871, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene 6888 Neighboring gene spermatogenesis associated 31 subfamily D, member 1C Neighboring gene major facilitator superfamily domain containing 14B Neighboring gene predicted gene 3785

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001374208.1NP_001361137.1  protease, serine 47 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC154713
      Consensus CDS
      CCDS88474.1
      UniProtKB/TrEMBL
      A0A1Y7VLR0
      Related
      ENSMUSP00000152310.2, ENSMUST00000222769.2
      Conserved Domains (1) summary
      cd00190
      Location:5245
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    2. NM_001374209.1NP_001361138.1  protease, serine 47 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC154713
      Related
      ENSMUST00000220767.2
      Conserved Domains (1) summary
      cd00190
      Location:1147
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      65192427..65200685 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006517493.3XP_006517556.1  protease, serine 47 isoform X2

      UniProtKB/TrEMBL
      A0A0N4SVQ0
      Conserved Domains (1) summary
      cd00190
      Location:74306
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    2. XM_006517492.2XP_006517555.1  protease, serine 47 isoform X1

      UniProtKB/TrEMBL
      A0A0N4SVQ0
      Related
      ENSMUSP00000145196.2, ENSMUST00000203968.3
      Conserved Domains (1) summary
      cd00190
      Location:74314
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...