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    LINC00581 long intergenic non-protein coding RNA 581 [ Homo sapiens (human) ]

    Gene ID: 100874531, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC00581provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 581provided by HGNC
    Primary source
    HGNC:HGNC:43840
    See related
    Ensembl:ENSG00000280989 AllianceGenome:HGNC:43840
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    linc-MBOAT1-4
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See LINC00581 in Genome Data Viewer
    Location:
    6p22.3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (21486061..21511892, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (21358735..21384564, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (21486292..21512123, complement)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene CDK5 regulatory subunit associated protein 1 like 1 Neighboring gene uncharacterized LOC105374966 Neighboring gene melanoma risk locus-associated MPRA allelic enhancer 6:21150224 Neighboring gene melanoma risk locus-associated MPRA allelic enhancer 6:21163919 Neighboring gene melanoma risk locus-associated MPRA allelic enhancers 6:21164131 and 6:21164145 Neighboring gene melanoma risk locus-associated MPRA allelic enhancer 6:21166705 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24135 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr6:21186041-21186767 Neighboring gene NANOG hESC enhancer GRCh37_chr6:21223372-21223889 Neighboring gene uncharacterized LOC107986578 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr6:21230452-21231651 Neighboring gene Sharpr-MPRA regulatory region 5810 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:21263602-21264102 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24136 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24137 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24138 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:21275814-21276318 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:21276319-21276823 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:21327213-21328056 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:21361231-21362046 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr6:21362047-21362861 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:21367138-21367689 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:21367690-21368242 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:21368243-21368793 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:21393485-21394340 Neighboring gene MPRA-validated peak5728 silencer Neighboring gene uncharacterized LOC107986579 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24141 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16986 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16985 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16984 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24140 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24139 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:21588011-21588668 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16983 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16982 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:21586838-21587370 Neighboring gene SRY-box transcription factor 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. A de novo balanced t(2;6)(p15;p22.3) in a patient with West Syndrome disrupts a lnc-RNA. Vandeweyer G, et al. Epilepsy Res, 2012 May. PMID 22245136
    2. lncRNAdb: a reference database for long noncoding RNAs. Amaral PP, et al. Nucleic Acids Res, 2011 Jan. PMID 21112873, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_103790.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AA910749, BX118339
      Related
      ENST00000630914.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

      Range
      21486061..21511892 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060930.1 Alternate T2T-CHM13v2.0

      Range
      21358735..21384564 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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