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    SNHG17 small nucleolar RNA host gene 17 [ Homo sapiens (human) ]

    Gene ID: 388796, updated on 10-Dec-2024

    Summary

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    Official Symbol
    SNHG17provided by HGNC
    Official Full Name
    small nucleolar RNA host gene 17provided by HGNC
    Primary source
    HGNC:HGNC:48600
    See related
    Ensembl:ENSG00000196756 MIM:620808; AllianceGenome:HGNC:48600
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Ubiquitous expression in bone marrow (RPKM 12.9), ovary (RPKM 5.2) and 25 other tissues See more
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    Genomic context

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    See SNHG17 in Genome Data Viewer
    Location:
    20q11.23
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (38420588..38435328, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (40148174..40162915, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (37049235..37063971, complement)

    Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:36982312-36982872 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:36982873-36983432 Neighboring gene H3K27ac hESC enhancer GRCh37_chr20:36986777-36987278 Neighboring gene lipopolysaccharide binding protein Neighboring gene ReSE screen-validated silencer GRCh37_chr20:36991245-36991414 Neighboring gene ReSE screen-validated silencer GRCh37_chr20:37017902-37018103 Neighboring gene uncharacterized LOC124904901 Neighboring gene small nucleolar RNA SNORA71 Neighboring gene Sharpr-MPRA regulatory region 13566 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:37059106-37059606 Neighboring gene uncharacterized LOC124904958 Neighboring gene small nucleolar RNA, H/ACA box 71B Neighboring gene small nucleolar RNA, H/ACA box 71A Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17856 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17857 Neighboring gene small nucleolar RNA, H/ACA box 71C Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17858 Neighboring gene small nucleolar RNA, H/ACA box 71D Neighboring gene small nucleolar RNA SNORA71 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17859 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:37076132-37076686 Neighboring gene small nucleolar RNA, H/ACA box 71E Neighboring gene small nucleolar RNA host gene 11

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Tumour-derived exosome SNHG17 induced by oestrogen contributes to ovarian cancer progression via the CCL13-CCR2-M2 macrophage axis. Liang H, et al. J Cell Mol Med, 2024 May. PMID 38680032, Free PMC Article
    2. LncRNA SNHG17 promotes gastric cancer progression by epigenetically silencing of p15 and p57. Zhang G, et al. J Cell Physiol, 2019 Apr. PMID 30256413
    3. The prognostic roles of long non-coding RNA SNHG17 in the patients with gastric cancer. Chen LL, et al. Eur Rev Med Pharmacol Sci, 2019 Feb. PMID 30779073
    4. Integrative Analysis and Experimental Validation Indicated That SNHG17 Is a Prognostic Marker in Prostate Cancer and a Modulator of the Tumor Microenvironment via a Competitive Endogenous RNA Regulatory Network. Li J, et al. Oxid Med Cell Longev, 2022. PMID 35864871, Free PMC Article
    5. SNHG17 enhances the malignant characteristics of tongue squamous cell carcinoma by acting as a competing endogenous RNA on microRNA-876 and thereby increasing specificity protein 1 expression. Liu X, et al. Cell Cycle, 2020 Mar. PMID 32089063, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Tumour-derived exosome SNHG17 induced by oestrogen contributes to ovarian cancer progression via the CCL13-CCR2-M2 macrophage axis.
      Title: Tumour-derived exosome SNHG17 induced by oestrogen contributes to ovarian cancer progression via the CCL13-CCR2-M2 macrophage axis.
    2. SNHG17 alters anaerobic glycolysis by resetting phosphorylation modification of PGK1 to foster pro-tumor macrophage formation in pancreatic ductal adenocarcinoma.
      Title: SNHG17 alters anaerobic glycolysis by resetting phosphorylation modification of PGK1 to foster pro-tumor macrophage formation in pancreatic ductal adenocarcinoma.
    3. Identification of two novel lipid metabolism-related long non-coding RNAs (SNHG17 and LINC00837) as potential signatures for osteosarcoma prognosis and precise treatment.
      Title: Identification of two novel lipid metabolism-related long non-coding RNAs (SNHG17 and LINC00837) as potential signatures for osteosarcoma prognosis and precise treatment.
    4. Lactobacillus rhamnosus GG ameliorates radiation-induced lung fibrosis via lncRNASNHG17/PTBP1/NICD axis modulation.
      Title: Lactobacillus rhamnosus GG ameliorates radiation-induced lung fibrosis via lncRNASNHG17/PTBP1/NICD axis modulation.
    5. Low SP1 SUMOylation-dependent SNHG17 upregulation promotes drug resistance of gastric cancer through impairing hsa-miR-23b-3p-induced Notch2 inhibition.
      Title: Low SP1 SUMOylation-dependent SNHG17 upregulation promotes drug resistance of gastric cancer through impairing hsa-miR-23b-3p-induced Notch2 inhibition.
    6. Silencing of lncRNA SNHG17 inhibits the tumorigenesis of epithelial ovarian cancer through regulation of miR-485-5p/AKT1 axis.
      Title: Silencing of lncRNA SNHG17 inhibits the tumorigenesis of epithelial ovarian cancer through regulation of miR-485-5p/AKT1 axis.
    7. Integrative Analysis and Experimental Validation Indicated That SNHG17 Is a Prognostic Marker in Prostate Cancer and a Modulator of the Tumor Microenvironment via a Competitive Endogenous RNA Regulatory Network.
      Title: Integrative Analysis and Experimental Validation Indicated That SNHG17 Is a Prognostic Marker in Prostate Cancer and a Modulator of the Tumor Microenvironment via a Competitive Endogenous RNA Regulatory Network.
    8. LncRNA SNHG17 predicts poor prognosis and promotes cell proliferation and migration in hepatocellular carcinoma.
      Title: LncRNA SNHG17 predicts poor prognosis and promotes cell proliferation and migration in hepatocellular carcinoma.
    9. LncRNA SNHG17 interacts with LRPPRC to stabilize c-Myc protein and promote G1/S transition and cell proliferation.
      Title: LncRNA SNHG17 interacts with LRPPRC to stabilize c-Myc protein and promote G1/S transition and cell proliferation.
    10. LncRNA SNHG17 regulates cell proliferation and invasion by targeting miR-338-3p/SOX4 axis in esophageal squamous cell carcinoma.
      Title: LncRNA SNHG17 regulates cell proliferation and invasion by targeting miR-338-3p/SOX4 axis in esophageal squamous cell carcinoma.
    Submit: New GeneRIF Correction See all GeneRIFs (25)

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Other Names

    • small nucleolar RNA host gene 17 (non-protein coding)

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_015366.6 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000690361.2

    2. NR_027241.4 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000660885.3

    3. NR_152753.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000781227.1

    4. NR_152754.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000665735.2

    5. NR_152755.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000665233.4

    6. NR_152756.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000663540.3

    7. NR_152757.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000689414.3

    8. NR_152758.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000666268.2

    9. NR_152759.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000781199.1

    10. NR_152760.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000781230.1

    11. NR_152761.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000456953.9

    12. NR_152762.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000654183.3

    13. NR_152763.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000781191.1

    14. NR_152764.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000417578.9

    15. NR_185920.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000658488.3

    16. NR_185921.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000781193.1

    17. NR_185922.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000662213.1

    18. NR_185923.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000781220.1

    19. NR_185924.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000657216.3

    20. NR_185925.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000651115.2

    21. NR_185926.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000653697.1

    22. NR_185927.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000781236.1

    23. NR_185928.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000701507.2

    24. NR_185929.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000687532.2

    25. NR_185930.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000781213.1

    26. NR_185931.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000655520.3

    27. NR_185932.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000666419.2

    28. NR_185934.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000701521.2

    29. NR_185935.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000701793.2

    30. NR_185936.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000671249.1

    31. NR_185937.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000664073.3

    32. NR_185938.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000701736.2

    33. NR_185939.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000689917.3

    34. NR_185940.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000666331.1

    35. NR_185941.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000658905.2

    36. NR_185942.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095

    37. NR_185943.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000665181.2

    38. NR_185944.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000692262.2

    39. NR_185945.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000781201.1

    40. NR_185946.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000661252.1

    41. NR_185947.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000660558.3

    42. NR_185948.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000669480.1

    43. NR_185949.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095

    44. NR_185950.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095

    45. NR_185951.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000668054.3

    46. NR_185952.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095

    47. NR_185953.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095

    48. NR_185954.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000781214.1

    49. NR_185955.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000687490.2

    50. NR_185956.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095

    51. NR_185957.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000436764.9

    52. NR_185958.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000664636.2

    53. NR_185959.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000669137.2

    54. NR_185960.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000657843.1

    55. NR_185961.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095

    56. NR_185962.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095

    57. NR_185963.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000670051.1

    58. NR_185964.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000669033.2

    59. NR_185965.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000656320.2

    60. NR_185966.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000781206.1

    61. NR_185967.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000690441.2

    62. NR_185968.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000781226.1

    63. NR_185969.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095

    64. NR_185970.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095

    65. NR_185972.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095

    66. NR_185973.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095

    67. NR_185974.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL391095
      Related
      ENST00000413755.7

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

      Range
      38420588..38435328 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060944.1 Alternate T2T-CHM13v2.0

      Range
      40148174..40162915 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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