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    Hbq1a hemoglobin, theta 1A [ Mus musculus (house mouse) ]

    Gene ID: 216635, updated on 9-Dec-2024

    Summary

    Official Symbol
    Hbq1aprovided by MGI
    Official Full Name
    hemoglobin, theta 1Aprovided by MGI
    Primary source
    MGI:MGI:2685722
    See related
    Ensembl:ENSMUSG00000020295 AllianceGenome:MGI:2685722
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Hbq1; Gm876; Hbqt2; A230090E05Rik
    Summary
    This gene is one of two mouse theta-globin genes found in the alpha-globin gene cluster on chromosome 11. This gene represents the T2 (or 3') theta-globin gene described in PMIDs 18245844 and 11157800, respectively. [provided by RefSeq, Apr 2009]
    Expression
    Biased expression in liver E14.5 (RPKM 26.4), liver E14 (RPKM 22.2) and 5 other tissues See more
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    Genomic context

    See Hbq1a in Genome Data Viewer
    Location:
    11 A4; 11 18.87 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (32250069..32250873)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (32300069..32300873)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene hemoglobin, theta 1B Neighboring gene hemoglobin alpha, adult chain 2 Neighboring gene predicted gene, 46275 Neighboring gene STARR-seq mESC enhancer starr_29106 Neighboring gene SH3 and PX domains 2B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to haptoglobin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables heme binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables oxygen binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables oxygen carrier activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    contributes_to peroxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in hydrogen peroxide catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of haptoglobin-hemoglobin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of hemoglobin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    hemoglobin, theta T2
    Names
    Hbq1 3'-theta
    hemoglobin, theta 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175000.2NP_778165.1  hemoglobin, theta T2

      See identical proteins and their annotated locations for NP_778165.1

      Status: PROVISIONAL

      Source sequence(s)
      AK039049
      Consensus CDS
      CCDS24525.1
      UniProtKB/TrEMBL
      B9EIX8, Q8BYM1
      Related
      ENSMUSP00000020535.2, ENSMUST00000020535.2
      Conserved Domains (1) summary
      cl21461
      Location:4121
      Globin_like; Globin-like proteins

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      32250069..32250873
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)