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    Srcin1 SRC kinase signaling inhibitor 1 [ Mus musculus (house mouse) ]

    Gene ID: 56013, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Srcin1provided by MGI
    Official Full Name
    SRC kinase signaling inhibitor 1provided by MGI
    Primary source
    MGI:MGI:1933179
    See related
    Ensembl:ENSMUSG00000038453 AllianceGenome:MGI:1933179
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    P140; SNIP; p140Cap; mKIAA1684
    Summary
    Predicted to enable protein domain specific binding activity and protein kinase binding activity. Involved in regulation of synapse assembly. Acts upstream of or within negative regulation of cell adhesion. Located in postsynaptic density. Is active in glutamatergic synapse and presynapse. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and respiratory system. Orthologous to human SRCIN1 (SRC kinase signaling inhibitor 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in cerebellum adult (RPKM 19.1), cortex adult (RPKM 17.2) and 10 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Srcin1 in Genome Data Viewer
    Location:
    11 D; 11 61.0 cM
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (97400166..97466059, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (97509340..97575246, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene suppressor of cytokine signaling 7 Neighboring gene STARR-seq mESC enhancer starr_30603 Neighboring gene STARR-positive B cell enhancer ABC_E10709 Neighboring gene Rho GTPase activating protein 23 Neighboring gene STARR-seq mESC enhancer starr_30610 Neighboring gene RIKEN cDNA 4933428G20 gene Neighboring gene STARR-positive B cell enhancer ABC_E11489 Neighboring gene STARR-positive B cell enhancer ABC_E11490 Neighboring gene STARR-positive B cell enhancer mm9_chr11:97394449-97394749 Neighboring gene STARR-seq mESC enhancer starr_30619 Neighboring gene RIKEN cDNA 2410003L11 gene Neighboring gene STARR-seq mESC enhancer starr_30621 Neighboring gene STARR-positive B cell enhancer ABC_E8449 Neighboring gene predicted gene, 38962 Neighboring gene elongin BC and polycomb repressive complex 2 associated protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. p140Cap Regulates the Composition and Localization of the NMDAR Complex in Synaptic Lipid Rafts. Angelini C, et al. J Neurosci, 2022 Sep 21. PMID 35953295, Free PMC Article
    2. Expression and function of SNAP-25 as a universal SNARE component in GABAergic neurons. Tafoya LC, et al. J Neurosci, 2006 Jul 26. PMID 16870728, Free PMC Article
    3. SNX17 Mediates Dendritic Spine Maturation via p140Cap. Cui Q, et al. Mol Neurobiol, 2024 Mar. PMID 37704928
    4. SNAP-25 regulates spine formation through postsynaptic binding to p140Cap. Tomasoni R, et al. Nat Commun, 2013. PMID 23868368
    5. p140Cap regulates memory and synaptic plasticity through Src-mediated and citron-N-mediated actin reorganization. Repetto D, et al. J Neurosci, 2014 Jan 22. PMID 24453341, Free PMC Article

    See all (53) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Circ-USP9X accelerates deep vein thrombosis after fracture by acting as a miR-148b-3p sponge and upregulates SRC kinase signaling inhibitor 1.
      Title: Circ-USP9X accelerates deep vein thrombosis after fracture by acting as a miR-148b-3p sponge and upregulates SRC kinase signaling inhibitor 1.
    2. SNX17 Mediates Dendritic Spine Maturation via p140Cap.
      Title: SNX17 Mediates Dendritic Spine Maturation via p140Cap.
    3. Deletion of p140Cap in forebrain interneurons resulted in increased inhibitory synaptogenesis.
      Title: p140Cap Regulates GABAergic Synaptogenesis and Development of Hippocampal Inhibitory Circuits.
    4. Study demonstrates a critical role of presynaptic cadherin/catenin/p140Cap cell adhesion complexes in stabilizing functional synapses and spines in the developing neocortex.
      Title: A Critical Role of Presynaptic Cadherin/Catenin/p140Cap Complexes in Stabilizing Spines and Functional Synapses in the Neocortex.
    5. these results reveal a novel function of postsynaptic endophilin A1 in spine morphogenesis, stabilization and synaptic function through the regulation of p140Cap
      Title: Endophilin A1 regulates dendritic spine morphogenesis and stability through interaction with p140Cap.
    6. we here demonstrate that p140Cap is a key element for both learning and synaptic plasticity
      Title: p140Cap regulates memory and synaptic plasticity through Src-mediated and citron-N-mediated actin reorganization.
    7. SNAP-25 regulates the organization of the molecular apparatus needed for dendritic spine formation by recruiting and stabilizing p140Cap.
      Title: SNAP-25 regulates spine formation through postsynaptic binding to p140Cap.
    8. p140Cap immobilizes E-cadherin at the cell membrane and inhibits EGFR and Erk1/2 signalling, blocking scatter and proliferation of cancer cells.
      Title: p140Cap dual regulation of E-cadherin/EGFR cross-talk and Ras signalling in tumour cell scatter and proliferation.
    9. Our results thus provide evidence that SNAP-25 is critical for evoked GABA release during development and is expressed in the presynaptic terminals of mature GABAergic neurons.
      Title: Expression and function of SNAP-25 as a universal SNARE component in GABAergic neurons.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (4)  1 citation

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein kinase binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within negative regulation of cell adhesion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in negative regulation of protein secretion ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of protein tyrosine kinase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of protein tyrosine kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of protein tyrosine kinase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of protein tyrosine kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in postsynaptic actin cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of cell migration ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of cell migration ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of dendritic spine morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of dendritic spine morphogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of dendritic spine morphogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of synapse assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of synapse assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in substrate adhesion-dependent cell spreading ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in substrate adhesion-dependent cell spreading ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    located_in axon ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in axon ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in dendrite ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in filopodium ISO
    Inferred from Sequence Orthology
    more info
    		  
    NOT located_in focal adhesion ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in glutamatergic synapse IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    is_active_in glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in lamellipodium ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in postsynaptic density IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in postsynaptic density IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in postsynaptic density ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in presynapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in synapse ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in synapse ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    SRC kinase signaling inhibitor 1
    Names
    Snap-25-interacting protein
    p130Cas-associated protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_018873.2 → NP_061361.2  SRC kinase signaling inhibitor 1

      See identical proteins and their annotated locations for NP_061361.2

      Status: VALIDATED

      Source sequence(s)
      AF040944, AK129422, AL596088, CJ061326
      Consensus CDS
      CCDS36294.1
      UniProtKB/TrEMBL
      A0A571BDG0, B1AQX9
      Related
      ENSMUSP00000103222.3, ENSMUST00000107596.9
      Conserved Domains (1) summary
      pfam03915
      Location:218 → 289
      AIP3; Actin interacting protein 3

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      97400166..97466059 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030246171.2 → XP_030102031.1  SRC kinase signaling inhibitor 1 isoform X24

      UniProtKB/TrEMBL
      A0A571BG39
      Related
      ENSMUSP00000158676.2, ENSMUST00000238342.2
      Conserved Domains (3) summary
      TIGR02169
      Location:696 → 850
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1070 → 1421
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:185 → 264
      AIP3; Actin interacting protein 3

    2. XM_030246172.2 → XP_030102032.1  SRC kinase signaling inhibitor 1 isoform X25

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (3) summary
      TIGR02169
      Location:679 → 833
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1053 → 1404
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:177 → 256
      AIP3; Actin interacting protein 3

    3. XM_036156862.1 → XP_036012755.1  SRC kinase signaling inhibitor 1 isoform X36

      UniProtKB/TrEMBL
      A0A571BDG0
      Related
      ENSMUSP00000158711.2, ENSMUST00000238314.2
      Conserved Domains (3) summary
      TIGR02169
      Location:719 → 873
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:218 → 315
      AIP3; Actin interacting protein 3
      NF033930
      Location:720 → 1031
      pneumo_PspA; pneumococcal surface protein A

    4. XM_017314677.3 → XP_017170166.1  SRC kinase signaling inhibitor 1 isoform X15

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (3) summary
      TIGR02169
      Location:729 → 883
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1103 → 1454
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:218 → 297
      AIP3; Actin interacting protein 3

    5. XM_036156860.1 → XP_036012753.1  SRC kinase signaling inhibitor 1 isoform X20

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (4) summary
      TIGR02169
      Location:719 → 873
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1093 → 1444
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:218 → 297
      AIP3; Actin interacting protein 3
      NF033930
      Location:720 → 1031
      pneumo_PspA; pneumococcal surface protein A

    6. XM_030246182.2 → XP_030102042.1  SRC kinase signaling inhibitor 1 isoform X42

      UniProtKB/TrEMBL
      A0A571BDG0
      Conserved Domains (2) summary
      TIGR02169
      Location:719 → 873
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:218 → 297
      AIP3; Actin interacting protein 3

    7. XM_030246185.2 → XP_030102045.1  SRC kinase signaling inhibitor 1 isoform X46

      UniProtKB/TrEMBL
      A0A571BDG0
      Related
      ENSMUSP00000158656.2, ENSMUST00000238233.2
      Conserved Domains (2) summary
      TIGR02169
      Location:672 → 826
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:170 → 249
      AIP3; Actin interacting protein 3

    8. XM_030246186.1 → XP_030102046.1  SRC kinase signaling inhibitor 1 isoform X47

      UniProtKB/TrEMBL
      A0A571BDG6
      Conserved Domains (2) summary
      TIGR02169
      Location:705 → 859
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:203 → 282
      AIP3; Actin interacting protein 3

    9. XM_036156861.1 → XP_036012754.1  SRC kinase signaling inhibitor 1 isoform X23

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (4) summary
      TIGR02169
      Location:705 → 859
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1079 → 1430
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:203 → 282
      AIP3; Actin interacting protein 3
      NF033930
      Location:706 → 1017
      pneumo_PspA; pneumococcal surface protein A

    10. XM_017314679.3 → XP_017170168.1  SRC kinase signaling inhibitor 1 isoform X21

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (3) summary
      TIGR02169
      Location:714 → 868
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1088 → 1439
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:203 → 282
      AIP3; Actin interacting protein 3

    11. XM_017314678.3 → XP_017170167.1  SRC kinase signaling inhibitor 1 isoform X21

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (3) summary
      TIGR02169
      Location:714 → 868
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1088 → 1439
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:203 → 282
      AIP3; Actin interacting protein 3

    12. XM_017314674.3 → XP_017170163.1  SRC kinase signaling inhibitor 1 isoform X12

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (2) summary
      TIGR02169
      Location:784 → 938
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:273 → 352
      AIP3; Actin interacting protein 3

    13. XM_017314669.3 → XP_017170158.1  SRC kinase signaling inhibitor 1 isoform X6

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (3) summary
      TIGR02169
      Location:763 → 917
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1137 → 1488
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:252 → 331
      AIP3; Actin interacting protein 3

    14. XM_017314670.3 → XP_017170159.1  SRC kinase signaling inhibitor 1 isoform X7

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (3) summary
      TIGR02169
      Location:751 → 905
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1125 → 1476
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:240 → 319
      AIP3; Actin interacting protein 3

    15. XM_017314668.3 → XP_017170157.1  SRC kinase signaling inhibitor 1 isoform X3

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (3) summary
      TIGR02169
      Location:776 → 930
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1150 → 1501
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:265 → 344
      AIP3; Actin interacting protein 3

    16. XM_017314667.3 → XP_017170156.1  SRC kinase signaling inhibitor 1 isoform X2

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (3) summary
      TIGR02169
      Location:783 → 937
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1157 → 1508
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:273 → 352
      AIP3; Actin interacting protein 3

    17. XM_017314672.3 → XP_017170161.1  SRC kinase signaling inhibitor 1 isoform X8

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (2) summary
      TIGR02169
      Location:784 → 938
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:273 → 352
      AIP3; Actin interacting protein 3

    18. XM_017314666.3 → XP_017170155.1  SRC kinase signaling inhibitor 1 isoform X1

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (3) summary
      TIGR02169
      Location:784 → 938
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1158 → 1509
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:273 → 352
      AIP3; Actin interacting protein 3

    19. XM_030246167.2 → XP_030102027.1  SRC kinase signaling inhibitor 1 isoform X17

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (3) summary
      TIGR02169
      Location:722 → 876
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1096 → 1447
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:211 → 290
      AIP3; Actin interacting protein 3

    20. XM_030246169.2 → XP_030102029.1  SRC kinase signaling inhibitor 1 isoform X19

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (3) summary
      TIGR02169
      Location:720 → 874
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1094 → 1445
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:219 → 298
      AIP3; Actin interacting protein 3

    21. XM_036156859.1 → XP_036012752.1  SRC kinase signaling inhibitor 1 isoform X14

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (4) summary
      TIGR02169
      Location:733 → 887
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1107 → 1458
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:232 → 311
      AIP3; Actin interacting protein 3
      NF033930
      Location:734 → 1045
      pneumo_PspA; pneumococcal surface protein A

    22. XM_017314671.3 → XP_017170160.1  SRC kinase signaling inhibitor 1 isoform X9

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (3) summary
      TIGR02169
      Location:743 → 897
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1117 → 1468
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:232 → 311
      AIP3; Actin interacting protein 3

    23. XM_030246163.2 → XP_030102023.1  SRC kinase signaling inhibitor 1 isoform X11

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (3) summary
      TIGR02169
      Location:741 → 895
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1115 → 1466
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:240 → 319
      AIP3; Actin interacting protein 3

    24. XM_030246162.2 → XP_030102022.1  SRC kinase signaling inhibitor 1 isoform X5

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (3) summary
      TIGR02169
      Location:774 → 928
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1148 → 1499
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:273 → 352
      AIP3; Actin interacting protein 3

    25. XM_006533765.5 → XP_006533828.1  SRC kinase signaling inhibitor 1 isoform X4

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (3) summary
      TIGR02169
      Location:775 → 929
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1149 → 1500
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:273 → 352
      AIP3; Actin interacting protein 3

    26. XM_030246170.2 → XP_030102030.1  SRC kinase signaling inhibitor 1 isoform X22

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (3) summary
      TIGR02169
      Location:713 → 867
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1087 → 1438
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:211 → 290
      AIP3; Actin interacting protein 3

    27. XM_030246168.2 → XP_030102028.1  SRC kinase signaling inhibitor 1 isoform X18

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (3) summary
      TIGR02169
      Location:721 → 875
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1095 → 1446
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:219 → 298
      AIP3; Actin interacting protein 3

    28. XM_017314680.3 → XP_017170169.1  SRC kinase signaling inhibitor 1 isoform X26

      UniProtKB/TrEMBL
      A0A571BDG0
      Conserved Domains (2) summary
      TIGR02169
      Location:784 → 938
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:273 → 352
      AIP3; Actin interacting protein 3

    29. XM_030246173.2 → XP_030102033.1  SRC kinase signaling inhibitor 1 isoform X27

      UniProtKB/TrEMBL
      A0A571BDG0
      Conserved Domains (2) summary
      TIGR02169
      Location:775 → 929
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:273 → 352
      AIP3; Actin interacting protein 3

    30. XM_030246174.2 → XP_030102034.1  SRC kinase signaling inhibitor 1 isoform X29

      UniProtKB/Swiss-Prot
      O70298, Q9QWI6
      Conserved Domains (2) summary
      TIGR02169
      Location:783 → 937
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:273 → 352
      AIP3; Actin interacting protein 3

    31. XM_030246180.2 → XP_030102040.1  SRC kinase signaling inhibitor 1 isoform X40

      UniProtKB/Swiss-Prot
      O70298, Q9QWI6
      Conserved Domains (2) summary
      TIGR02169
      Location:783 → 937
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:273 → 352
      AIP3; Actin interacting protein 3

    32. XM_017314681.3 → XP_017170170.1  SRC kinase signaling inhibitor 1 isoform X28

      UniProtKB/Swiss-Prot
      O70298, Q9QWI6
      Conserved Domains (2) summary
      TIGR02169
      Location:784 → 938
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:273 → 352
      AIP3; Actin interacting protein 3

    33. XM_030246179.2 → XP_030102039.1  SRC kinase signaling inhibitor 1 isoform X39

      UniProtKB/Swiss-Prot
      O70298, Q9QWI6
      Conserved Domains (2) summary
      TIGR02169
      Location:784 → 938
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:273 → 352
      AIP3; Actin interacting protein 3

    34. XM_030246177.2 → XP_030102037.1  SRC kinase signaling inhibitor 1 isoform X34

      UniProtKB/TrEMBL
      A0A571BDG0
      Conserved Domains (2) summary
      TIGR02169
      Location:733 → 887
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:232 → 311
      AIP3; Actin interacting protein 3

    35. XM_006533781.5 → XP_006533844.1  SRC kinase signaling inhibitor 1 isoform X38

      UniProtKB/Swiss-Prot
      O70298, Q9QWI6
      Conserved Domains (2) summary
      TIGR02169
      Location:741 → 895
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:240 → 319
      AIP3; Actin interacting protein 3

    36. XM_030246183.2 → XP_030102043.1  SRC kinase signaling inhibitor 1 isoform X43

      UniProtKB/TrEMBL
      A0A571BDG6
      Conserved Domains (2) summary
      TIGR02169
      Location:751 → 905
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:240 → 319
      AIP3; Actin interacting protein 3

    37. XM_030246175.2 → XP_030102035.1  SRC kinase signaling inhibitor 1 isoform X32

      UniProtKB/Swiss-Prot
      O70298, Q9QWI6
      Conserved Domains (2) summary
      TIGR02169
      Location:774 → 928
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:273 → 352
      AIP3; Actin interacting protein 3

    38. XM_006533779.5 → XP_006533842.1  SRC kinase signaling inhibitor 1 isoform X31

      UniProtKB/Swiss-Prot
      O70298, Q9QWI6
      Conserved Domains (2) summary
      TIGR02169
      Location:775 → 929
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:273 → 352
      AIP3; Actin interacting protein 3

    39. XM_006533782.5 → XP_006533845.1  SRC kinase signaling inhibitor 1 isoform X41

      UniProtKB/Swiss-Prot
      O70298, Q9QWI6
      Conserved Domains (2) summary
      TIGR02169
      Location:775 → 929
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:273 → 352
      AIP3; Actin interacting protein 3

    40. XM_030246184.2 → XP_030102044.1  SRC kinase signaling inhibitor 1 isoform X45

      UniProtKB/TrEMBL
      A0A571BDG6, B1AQX6
      Related
      ENSMUSP00000103219.2, ENSMUST00000107593.8
      Conserved Domains (2) summary
      TIGR02169
      Location:721 → 875
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:219 → 298
      AIP3; Actin interacting protein 3

    41. XM_017314673.2 → XP_017170162.1  SRC kinase signaling inhibitor 1 isoform X10

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (3) summary
      TIGR02169
      Location:743 → 897
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1117 → 1468
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:232 → 311
      AIP3; Actin interacting protein 3

    42. XM_030246165.2 → XP_030102025.1  SRC kinase signaling inhibitor 1 isoform X16

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (3) summary
      TIGR02169
      Location:726 → 880
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1100 → 1451
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:224 → 303
      AIP3; Actin interacting protein 3

    43. XM_030246164.2 → XP_030102024.1  SRC kinase signaling inhibitor 1 isoform X13

      UniProtKB/TrEMBL
      A0A571BG39
      Conserved Domains (3) summary
      TIGR02169
      Location:734 → 888
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05109
      Location:1108 → 1459
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam03915
      Location:232 → 311
      AIP3; Actin interacting protein 3

    44. XM_006533783.5 → XP_006533846.1  SRC kinase signaling inhibitor 1 isoform X44

      UniProtKB/TrEMBL
      A0A571BDG6, B1AQX7
      Related
      ENSMUSP00000103216.2, ENSMUST00000107590.9
      Conserved Domains (2) summary
      TIGR02169
      Location:721 → 875
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:219 → 298
      AIP3; Actin interacting protein 3

    45. XM_030246178.2 → XP_030102038.1  SRC kinase signaling inhibitor 1 isoform X35

      UniProtKB/Swiss-Prot
      O70298, Q9QWI6
      Conserved Domains (2) summary
      TIGR02169
      Location:774 → 928
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:273 → 352
      AIP3; Actin interacting protein 3

    46. XM_017314682.3 → XP_017170171.1  SRC kinase signaling inhibitor 1 isoform X30

      UniProtKB/Swiss-Prot
      O70298, Q9QWI6
      Conserved Domains (2) summary
      TIGR02169
      Location:784 → 938
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:273 → 352
      AIP3; Actin interacting protein 3

    47. XM_030246176.2 → XP_030102036.1  SRC kinase signaling inhibitor 1 isoform X33

      UniProtKB/Swiss-Prot
      O70298, Q9QWI6
      Conserved Domains (2) summary
      TIGR02169
      Location:775 → 929
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:273 → 352
      AIP3; Actin interacting protein 3

    48. XM_017314683.3 → XP_017170172.1  SRC kinase signaling inhibitor 1 isoform X37

      UniProtKB/TrEMBL
      A0A571BDG6
      Conserved Domains (2) summary
      TIGR02169
      Location:784 → 938
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam03915
      Location:273 → 352
      AIP3; Actin interacting protein 3

    RNA

    1. XR_001780031.3 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9QWI6.2 GenPept UniProtKB/Swiss-Prot:Q9QWI6

    Gene LinkOut

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