Ppp1r27 protein phosphatase 1, regulatory subunit 27 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ppp1r27provided by MGI
Official Full Name: protein phosphatase 1, regulatory subunit 27provided by MGI
Primary source: MGI:MGI:1915951
See related: Ensembl:ENSMUSG00000025129 AllianceGenome:MGI:1915951
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: toonin; Dysfip1; 1110033I14Rik
Summary: Predicted to enable phosphatase binding activity. Orthologous to human PPP1R27 (protein phosphatase 1 regulatory subunit 27). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in mammary gland adult (RPKM 26.3), testis adult (RPKM 11.5) and 2 other tissues See more
Orthologs: human all
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Genomic context

Location:: 11 E2; 11 84.26 cM

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (120440801..120441958, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (120549975..120551132, complement)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables phosphatase binding	IBA Inferred from Biological aspect of Ancestor more info
enables phosphatase binding	ISO Inferred from Sequence Orthology more info
enables phosphatase binding	ISS Inferred from Sequence or Structural Similarity more info
enables protein phosphatase inhibitor activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: protein phosphatase 1 regulatory subunit 27

Names: dysferlin-interacting protein 1; ortholog of human dysferlin interacting protein 1 (toonin) DYSFP1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_026814.3 → NP_081090.1 protein phosphatase 1 regulatory subunit 27

See identical proteins and their annotated locations for NP_081090.1

Status: PROVISIONAL

Source sequence(s)

AK004064

Consensus CDS

CCDS36392.1

UniProtKB/Swiss-Prot

A2ABX5, Q9D119

Related

ENSMUSP00000026121.3, ENSMUST00000026121.3

Conserved Domains (3) summary

cd00204
Location:38 → 147

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam12796
Location:38 → 127

Ank_2; Ankyrin repeats (3 copies)

sd00045
Location:63 → 94

ANK; ANK repeat [structural motif]