U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Lncenc1 long non-coding RNA, embryonic stem cells expressed 1 [ Mus musculus (house mouse) ]

    Gene ID: 100039691, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Lncenc1provided by MGI
    Official Full Name
    long non-coding RNA, embryonic stem cells expressed 1provided by MGI
    Primary source
    MGI:MGI:3780541
    See related
    Ensembl:ENSMUSG00000078952 AllianceGenome:MGI:3780541
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm2373; Gm11019; Platr18; Lincenc1; linc-Enc1
    Summary
    Acts upstream of or within regulation of gene expression. Is expressed in brain. Orthologous to human LINC01157 (long intergenic non-protein coding RNA 1157). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Lncenc1 in Genome Data Viewer
    Location:
    13 D1; 13 50.71 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (97571441..97641366)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (97434970..97497664)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33390 Neighboring gene STARR-seq mESC enhancer starr_35381 Neighboring gene STARR-seq mESC enhancer starr_35383 Neighboring gene predicted gene, 33447 Neighboring gene STARR-seq mESC enhancer starr_35388 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:98212351-98212677 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene 2379 Neighboring gene predicted gene, 41030

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A proinflammatory long noncoding RNA Lncenc1 regulates inflammasome activation in macrophage. Han Y, et al. Am J Physiol Lung Cell Mol Physiol, 2023 May 1. PMID 36880658, Free PMC Article
    2. LncRNA embryonic stem cells expressed 1 (Lncenc1) is identified as a novel regulator in neuropathic pain by interacting with EZH2 and downregulating the expression of Bai1 in mouse microglia. Zhang Z, et al. Exp Cell Res, 2021 Feb 1. PMID 33340495
    3. The Long Noncoding RNA Lncenc1 Maintains Naive States of Mouse ESCs by Promoting the Glycolysis Pathway. Sun Z, et al. Stem Cell Reports, 2018 Sep 11. PMID 30174313, Free PMC Article
    4. Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain. Goff LA, et al. Proc Natl Acad Sci U S A, 2015 Jun 2. PMID 26034286, Free PMC Article
    5. Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs. Lai KM, et al. PLoS One, 2015. PMID 25909911, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A proinflammatory long noncoding RNA Lncenc1 regulates inflammasome activation in macrophage.
      Title: A proinflammatory long noncoding RNA Lncenc1 regulates inflammasome activation in macrophage.
    2. LncRNA embryonic stem cells expressed 1 (Lncenc1) is identified as a novel regulator in neuropathic pain by interacting with EZH2 and downregulating the expression of Bai1 in mouse microglia.
      Title: LncRNA embryonic stem cells expressed 1 (Lncenc1) is identified as a novel regulator in neuropathic pain by interacting with EZH2 and downregulating the expression of Bai1 in mouse microglia.
    3. A long non-coding RNA specifically expressed in early embryos programs the metabolic balance in adult mice.
      Title: A long non-coding RNA specifically expressed in early embryos programs the metabolic balance in adult mice.
    Submit: New GeneRIF Correction

    Variation

    Go to the top of the page Help

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Go to the top of the page Help

    Other Names

    • long intergenic non-coding RNA, embryonic stem cells expressed 1

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_110430.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript.
      Source sequence(s)
      AC124581
      Related
      ENSMUST00000179324.2

    2. NR_110431.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an internal exon, resulting in a shorter transcript, compared to variant 1.
      Source sequence(s)
      AC124581
      Related
      ENSMUST00000246094.1

    3. NR_110432.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks two exons and contains an alternate 5' terminal exon, resulting in a shorter transcript, compared to variant 1.
      Source sequence(s)
      AC124581, CT030035
      Related
      ENSMUST00000109431.10

    4. NR_188726.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124581, CT030035

    5. NR_188727.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124581

    6. NR_188728.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124581, CT030035

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      97571441..97641366
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.