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    Spmip4 sperm microtubule inner protein 4 [ Mus musculus (house mouse) ]

    Gene ID: 70821, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Spmip4provided by MGI
    Official Full Name
    sperm microtubule inner protein 4provided by MGI
    Primary source
    MGI:MGI:1918071
    See related
    Ensembl:ENSMUSG00000029828 AllianceGenome:MGI:1918071
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    TISP74; 4921507P07Rik
    Summary
    Predicted to be located in cytoplasm and motile cilium. Predicted to be active in centrosome. Orthologous to human SPMIP4 (sperm microtubule inner protein 4). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 82.5) See more
    Orthologs
    human all
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    Genomic context

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    See Spmip4 in Genome Data Viewer
    Location:
    6 B2.3; 6 24.32 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (50550282..50573847, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (50573302..50596852, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 5430402O13 gene Neighboring gene cytochrome c, somatic Neighboring gene microRNA 6371 Neighboring gene STARR-positive B cell enhancer ABC_E3655 Neighboring gene predicted gene, 38807 Neighboring gene STARR-seq mESC enhancer starr_15852 Neighboring gene Crn, crooked neck-like 1 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction†. Sun J, et al. Biol Reprod, 2020 Aug 4. PMID 32588039, Free PMC Article
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in centrosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in motile cilium IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    sperm-associated microtubule inner protein 4
    Names
    sperm associated microtubule inner protein 4
    uncharacterized protein C7orf31 homolog

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001417718.1 → NP_001404647.1  sperm-associated microtubule inner protein 4

      Status: VALIDATED

      Source sequence(s)
      AC153386
      UniProtKB/Swiss-Prot
      Q8K4U1, Q9D5Y0

    2. NM_027564.4 → NP_081840.1  sperm-associated microtubule inner protein 4

      See identical proteins and their annotated locations for NP_081840.1

      Status: VALIDATED

      Source sequence(s)
      AC153386
      Consensus CDS
      CCDS20132.1
      UniProtKB/Swiss-Prot
      Q8K4U1, Q9D5Y0
      UniProtKB/TrEMBL
      Q3TT91
      Related
      ENSMUSP00000031852.5, ENSMUST00000031852.5
      Conserved Domains (1) summary
      pfam15093
      Location:1 → 283
      DUF4555; Domain of unknown function (DUF4555)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      50550282..50573847 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036152303.1 → XP_036008196.1  sperm-associated microtubule inner protein 4 isoform X1

      UniProtKB/Swiss-Prot
      Q8K4U1, Q9D5Y0
      UniProtKB/TrEMBL
      Q3TT91
      Conserved Domains (1) summary
      pfam15093
      Location:1 → 283
      DUF4555; Domain of unknown function (DUF4555)

    2. XM_006506605.1 → XP_006506668.1  sperm-associated microtubule inner protein 4 isoform X1

      See identical proteins and their annotated locations for XP_006506668.1

      UniProtKB/Swiss-Prot
      Q8K4U1, Q9D5Y0
      UniProtKB/TrEMBL
      Q3TT91
      Conserved Domains (1) summary
      pfam15093
      Location:1 → 283
      DUF4555; Domain of unknown function (DUF4555)

    3. XM_006506606.5 → XP_006506669.1  sperm-associated microtubule inner protein 4 isoform X2

      Conserved Domains (1) summary
      pfam15093
      Location:1 → 283
      DUF4555; Domain of unknown function (DUF4555)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D5Y0.1 GenPept UniProtKB/Swiss-Prot:Q9D5Y0

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