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    kdpA K(+) transporting P-type ATPase subunit KdpA [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946045, updated on 17-Dec-2024

    Summary

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    Official Symbol
    kdpA
    Official Full Name
    K(+) transporting P-type ATPase subunit KdpA
    Primary source
    ECOCYC:EG10513
    Locus tag
    b0698
    See related
    ASAP:ABE-0002381
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0686; kac
    Summary
    The kdpFABC genes encode an ATP-dependent high affinity P-Type ATPase potassium ion transporter . [More information is available at EcoCyc: EG10513].
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    Genomic context

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    Sequence:
    NC_000913.3 (727059..728732, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene sensor histidine kinase KdpD Neighboring gene K(+) transporting P-type ATPase subunit KdpC Neighboring gene K(+) transporting P-type ATPase subunit KdpB Neighboring gene K(+) transporting P-type ATPase subunit KdpF Neighboring gene DUF2517 domain-containing protein YbfA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence-directed DNA curvature in activator-binding sequence in the Escherichia coli kdp ABC promoter. Sugiura A, et al. Biosci Biotechnol Biochem, 1993 Feb. PMID 7763498
    2. Repressive control of potassium transport in Escherichia coli. Goldman D, et al. Biochim Biophys Acta, 1966 Dec 28. PMID 5339720
    3. The activity of the high-affinity K+ uptake system Kdp sensitizes cells of Escherichia coli to methylglyoxal. Ferguson GP, et al. J Bacteriol, 1996 Jul. PMID 8682804, Free PMC Article
    4. Identification of the structural proteins of an ATP-driven potassium transport system in Escherichia coli. Laimins LA, et al. Proc Natl Acad Sci U S A, 1978 Jul. PMID 356049, Free PMC Article
    5. Cation transport in Escherichia coli. IX. Regulation of K transport. Rhoads DB, et al. J Gen Physiol, 1978 Sep. PMID 359759, Free PMC Article

    See all (58) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Structural basis for potassium transport in prokaryotes by KdpFABC.
      Title: Structural basis for potassium transport in prokaryotes by KdpFABC.
    2. Data indicate that KdpFABC P-type ATPase activity could be stimulated not only by the presence of the transported K+ ions in a pH-dependent manner but also, to a significantly lesser extent, by H+ and Na+.
      Title: Mechanistic analysis of the pump cycle of the KdpFABC P-type ATPase.
    3. Data show that the increase in the anionic lipid composition enhances the expression rate of the kdpFABC operon.
      Title: Influence of K+-dependent membrane lipid composition on the expression of the kdpFABC operon in Escherichia coli.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables P-type potassium transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables P-type potassium transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables P-type potassium transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables potassium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within monoatomic cation transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in potassium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within potassium ion transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within potassium ion transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in potassium ion transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in potassium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    part_of potassium ion-transporting ATPase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of potassium:proton antiporter complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    K(+) transporting P-type ATPase subunit KdpA
    NP_415226.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      727059..728732 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415226.1 K(+) transporting P-type ATPase subunit KdpA [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415226.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A3K0WFQ6
      Conserved Domains (1) summary
      PRK05482
      Location:1 → 557
      PRK05482; potassium-transporting ATPase subunit A; Provisional
    Nucleotide Protein
    Heading Accession and Version

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