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    xapB xanthosine:H(+) symporter XapB [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946868, updated on 3-Dec-2024

    Summary

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    Official Symbol
    xapB
    Official Full Name
    xanthosine:H(+) symporter XapB
    Primary source
    ECOCYC:EG13159
    Locus tag
    b2406
    See related
    ASAP:ABE-0007925
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2400
    Summary
    NupG, XapB and YegT are paralogs. [More information is available at EcoGene: EG13159]. XapB is a probable xanthosine transporter. [More information is available at EcoCyc: EG13159].
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    Genomic context

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    Sequence:
    NC_000913.3 (2522729..2523985, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA-Lys Neighboring gene DNA-binding transcriptional activator XapR Neighboring gene xanthosine phosphorylase Neighboring gene putative outer membrane porin YfeN

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Specificity and topology of the Escherichia coli xanthosine permease, a representative of the NHS subfamily of the major facilitator superfamily. Nørholm MH, et al. J Bacteriol, 2001 Aug. PMID 11466294, Free PMC Article
    2. Identification and characterization of genes (xapA, xapB, and xapR) involved in xanthosine catabolism in Escherichia coli. Seeger C, et al. J Bacteriol, 1995 Oct. PMID 7559336, Free PMC Article
    3. Microbial drug efflux proteins of the major facilitator superfamily. Saidijam M, et al. Curr Drug Targets, 2006 Jul. PMID 16842212
    4. The major facilitator superfamily. Saier MH Jr, et al. J Mol Microbiol Biotechnol, 1999 Nov. PMID 10943556
    5. A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport. Marger MD, et al. Trends Biochem Sci, 1993 Jan. PMID 8438231

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables cytidine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nucleoside transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleoside transmembrane transporter activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables uridine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables xanthosine transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytidine transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within nucleobase-containing small molecule metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nucleoside transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in nucleoside transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within nucleoside transport ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in uridine transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in xanthosine transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    xanthosine:H(+) symporter XapB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2522729..2523985 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416901.1 xanthosine:H(+) symporter XapB [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416901.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7TPD8
      Conserved Domains (1) summary
      TIGR00889
      Location:1 → 418
      2A0110; nucleoside transporter
    Nucleotide Protein
    Heading Accession and Version

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