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    Hebp1 heme binding protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 15199, updated on 9-Dec-2024

    Summary

    Official Symbol
    Hebp1provided by MGI
    Official Full Name
    heme binding protein 1provided by MGI
    Primary source
    MGI:MGI:1333880
    See related
    Ensembl:ENSMUSG00000042770 AllianceGenome:MGI:1333880
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Hebp; p22HBP
    Summary
    Enables heme binding activity. Predicted to act upstream of or within heme metabolic process. Located in cytosol. Orthologous to human HEBP1 (heme binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in liver E14 (RPKM 81.5), liver adult (RPKM 79.6) and 17 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Hebp1 in Genome Data Viewer
    Location:
    6 G1; 6 65.93 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (135114517..135145213, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (135137519..135168215, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor, family C, group 5, member D Neighboring gene Hebp1R1 erythroid cis-regulatory module Neighboring gene STARR-seq mESC enhancer starr_17563 Neighboring gene fucose mutarotase-like Neighboring gene Hebp1R3 erythroid cis-regulatory module Neighboring gene predicted gene, 22881 Neighboring gene Hebp1R2 erythroid cis-regulatory module Neighboring gene predicted gene, 34391 Neighboring gene predicted gene, 19434 Neighboring gene predicted gene, 36533

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    heme-binding protein 1
    Names
    p22 HBP

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013546.3NP_038574.3  heme-binding protein 1

      Status: VALIDATED

      Source sequence(s)
      AC131718, AI527209, AK008919, BY242687
      Consensus CDS
      CCDS20645.1
      UniProtKB/Swiss-Prot
      O88814, Q9R257
      UniProtKB/TrEMBL
      A0A140T8J4
      Related
      ENSMUSP00000042232.8, ENSMUST00000045855.9
      Conserved Domains (1) summary
      pfam04832
      Location:13188
      SOUL; SOUL heme-binding protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      135114517..135145213 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011241224.3XP_011239526.1  heme-binding protein 1 isoform X1

      Conserved Domains (1) summary
      pfam04832
      Location:60222
      SOUL; SOUL heme-binding protein