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    Igdcc4 immunoglobulin superfamily, DCC subclass, member 4 [ Mus musculus (house mouse) ]

    Gene ID: 56741, updated on 9-Dec-2024

    Summary

    Official Symbol
    Igdcc4provided by MGI
    Official Full Name
    immunoglobulin superfamily, DCC subclass, member 4provided by MGI
    Primary source
    MGI:MGI:1858497
    See related
    Ensembl:ENSMUSG00000032816 AllianceGenome:MGI:1858497
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Nope; DDM36
    Summary
    Predicted to be involved in cell-cell adhesion. Predicted to be located in plasma membrane. Is expressed in several structures, including central nervous system; embryo mesenchyme; foregut; limb; and liver and biliary system. Orthologous to human IGDCC4 (immunoglobulin superfamily DCC subclass member 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in limb E14.5 (RPKM 23.8), ovary adult (RPKM 16.8) and 21 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Igdcc4 in Genome Data Viewer
    Location:
    9 C; 9 35.1 cM
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (65008246..65045225)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (65101023..65137947)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E9330 Neighboring gene predicted gene, 39362 Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 pseudogene Neighboring gene dipeptidylpeptidase 8 Neighboring gene STARR-seq mESC enhancer starr_24441 Neighboring gene immunoglobulin superfamily, DCC subclass, member 3 Neighboring gene STARR-seq mESC enhancer starr_24448 Neighboring gene predicted gene, 40527 Neighboring gene predicted gene, 25313

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Clone Names

    • mKIAA1628, 9330155G14Rik

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in cell-cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in plasma membrane ISA
    Inferred from Sequence Alignment
    more info
    PubMed 

    General protein information

    Preferred Names
    immunoglobulin superfamily DCC subclass member 4
    Names
    amplimer WI-16786, mouse homolog
    amplimer WI-18508, mouse homolog
    neighbor of Punc e11 protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001290315.2NP_001277244.1  immunoglobulin superfamily DCC subclass member 4 isoform 1 precursor

      See identical proteins and their annotated locations for NP_001277244.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC122463, AC161366
      Consensus CDS
      CCDS72258.1
      Related
      ENSMUSP00000045387.4, ENSMUST00000035499.5
      Conserved Domains (6) summary
      smart00408
      Location:155217
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:249330
      IG_like; Immunoglobulin like
      cd00063
      Location:850942
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:334421
      I-set; Immunoglobulin I-set domain
      pfam00041
      Location:429514
      fn3; Fibronectin type III domain
      cl11960
      Location:349421
      Ig; Immunoglobulin domain
    2. NM_020043.4NP_064427.2  immunoglobulin superfamily DCC subclass member 4 isoform 2 precursor

      See identical proteins and their annotated locations for NP_064427.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site in the central coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.
      Source sequence(s)
      AC122463, AC161366
      Consensus CDS
      CCDS90598.1
      UniProtKB/Swiss-Prot
      Q80TB0, Q9EQS8, Q9EQS9, Q9JLI1
      Related
      ENSMUSP00000150272.2, ENSMUST00000213533.2
      Conserved Domains (6) summary
      smart00408
      Location:155217
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:249330
      IG_like; Immunoglobulin like
      cd00063
      Location:849941
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:334421
      I-set; Immunoglobulin I-set domain
      pfam00041
      Location:429514
      fn3; Fibronectin type III domain
      cl11960
      Location:349421
      Ig; Immunoglobulin domain

    RNA

    1. NR_185285.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC122463, AC161366

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      65008246..65045225
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036155152.1XP_036011045.1  immunoglobulin superfamily DCC subclass member 4 isoform X15

      Conserved Domains (6) summary
      smart00410
      Location:256337
      IG_like; Immunoglobulin like
      cd00063
      Location:856948
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:436521
      fn3; Fibronectin type III domain
      pfam07679
      Location:151236
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:357365
      Ig; Ig strand B [structural motif]
      cl11960
      Location:356428
      Ig; Immunoglobulin domain
    2. XM_030244474.1XP_030100334.1  immunoglobulin superfamily DCC subclass member 4 isoform X13

      Conserved Domains (4) summary
      smart00409
      Location:169
      IG; Immunoglobulin
      cd00063
      Location:595687
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:168251
      fn3; Fibronectin type III domain
      cl11960
      Location:88160
      Ig; Immunoglobulin domain
    3. XM_030244472.1XP_030100332.1  immunoglobulin superfamily DCC subclass member 4 isoform X12

      Conserved Domains (4) summary
      smart00409
      Location:169
      IG; Immunoglobulin
      cd00063
      Location:596688
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:168251
      fn3; Fibronectin type III domain
      cl11960
      Location:88160
      Ig; Immunoglobulin domain
    4. XM_006511310.3XP_006511373.1  immunoglobulin superfamily DCC subclass member 4 isoform X5

      Conserved Domains (5) summary
      smart00409
      Location:249330
      IG; Immunoglobulin
      cd00063
      Location:857949
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:429512
      fn3; Fibronectin type III domain
      pfam07679
      Location:144229
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:349421
      Ig; Immunoglobulin domain
    5. XM_030244467.2XP_030100327.1  immunoglobulin superfamily DCC subclass member 4 isoform X6

      Conserved Domains (5) summary
      smart00410
      Location:249330
      IG_like; Immunoglobulin like
      cd00063
      Location:856948
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:429512
      fn3; Fibronectin type III domain
      pfam07679
      Location:144229
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:349421
      Ig; Immunoglobulin domain
    6. XM_036155150.1XP_036011043.1  immunoglobulin superfamily DCC subclass member 4 isoform X10

      Conserved Domains (6) summary
      smart00410
      Location:249330
      IG_like; Immunoglobulin like
      cd00063
      Location:802894
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:577671
      fn3; Fibronectin type III domain
      pfam07679
      Location:144229
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:350358
      Ig; Ig strand B [structural motif]
      cl11960
      Location:349421
      Ig; Immunoglobulin domain
    7. XM_030244469.2XP_030100329.1  immunoglobulin superfamily DCC subclass member 4 isoform X11

      Conserved Domains (5) summary
      smart00409
      Location:249330
      IG; Immunoglobulin
      cd00063
      Location:801893
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:576670
      fn3; Fibronectin type III domain
      pfam07679
      Location:144229
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:349421
      Ig; Immunoglobulin domain
    8. XM_006511311.3XP_006511374.1  immunoglobulin superfamily DCC subclass member 4 isoform X7

      Conserved Domains (5) summary
      smart00410
      Location:301382
      IG_like; Immunoglobulin like
      cd00063
      Location:854946
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:629723
      fn3; Fibronectin type III domain
      pfam07679
      Location:196281
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:401473
      Ig; Immunoglobulin domain
    9. XM_036155149.1XP_036011042.1  immunoglobulin superfamily DCC subclass member 4 isoform X8

      Conserved Domains (6) summary
      smart00410
      Location:301382
      IG_like; Immunoglobulin like
      cd00063
      Location:853945
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:628722
      fn3; Fibronectin type III domain
      pfam07679
      Location:196281
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:402410
      Ig; Ig strand B [structural motif]
      cl11960
      Location:401473
      Ig; Immunoglobulin domain
    10. XM_006511306.3XP_006511369.1  immunoglobulin superfamily DCC subclass member 4 isoform X1

      Conserved Domains (5) summary
      smart00409
      Location:301382
      IG; Immunoglobulin
      cd00063
      Location:9091001
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:481564
      fn3; Fibronectin type III domain
      pfam07679
      Location:196281
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:401473
      Ig; Immunoglobulin domain
    11. XM_006511308.1XP_006511371.1  immunoglobulin superfamily DCC subclass member 4 isoform X3

      Conserved Domains (5) summary
      smart00410
      Location:301382
      IG_like; Immunoglobulin like
      cd00063
      Location:902994
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:481564
      fn3; Fibronectin type III domain
      pfam07679
      Location:196281
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:401473
      Ig; Immunoglobulin domain
    12. XM_006511307.3XP_006511370.1  immunoglobulin superfamily DCC subclass member 4 isoform X2

      Conserved Domains (5) summary
      smart00409
      Location:301382
      IG; Immunoglobulin
      cd00063
      Location:9081000
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:481564
      fn3; Fibronectin type III domain
      pfam07679
      Location:196281
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:401473
      Ig; Immunoglobulin domain
    13. XM_006511309.1XP_006511372.1  immunoglobulin superfamily DCC subclass member 4 isoform X4

      Conserved Domains (5) summary
      smart00410
      Location:301382
      IG_like; Immunoglobulin like
      cd00063
      Location:901993
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:481564
      fn3; Fibronectin type III domain
      pfam07679
      Location:196281
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:401473
      Ig; Immunoglobulin domain
    14. XM_030244468.2XP_030100328.1  immunoglobulin superfamily DCC subclass member 4 isoform X9

      Conserved Domains (5) summary
      smart00410
      Location:301382
      IG_like; Immunoglobulin like
      cd00063
      Location:846938
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:628722
      fn3; Fibronectin type III domain
      pfam07679
      Location:196281
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:401473
      Ig; Immunoglobulin domain
    15. XM_030244471.2XP_030100331.1  immunoglobulin superfamily DCC subclass member 4 isoform X12

      Conserved Domains (4) summary
      smart00409
      Location:169
      IG; Immunoglobulin
      cd00063
      Location:596688
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:168251
      fn3; Fibronectin type III domain
      cl11960
      Location:88160
      Ig; Immunoglobulin domain
    16. XM_030244473.2XP_030100333.1  immunoglobulin superfamily DCC subclass member 4 isoform X12

      Conserved Domains (4) summary
      smart00409
      Location:169
      IG; Immunoglobulin
      cd00063
      Location:596688
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:168251
      fn3; Fibronectin type III domain
      cl11960
      Location:88160
      Ig; Immunoglobulin domain
    17. XM_030244470.2XP_030100330.1  immunoglobulin superfamily DCC subclass member 4 isoform X12

      Conserved Domains (4) summary
      smart00409
      Location:169
      IG; Immunoglobulin
      cd00063
      Location:596688
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:168251
      fn3; Fibronectin type III domain
      cl11960
      Location:88160
      Ig; Immunoglobulin domain
    18. XM_036155151.1XP_036011044.1  immunoglobulin superfamily DCC subclass member 4 isoform X14

      Conserved Domains (5) summary
      smart00409
      Location:169
      IG; Immunoglobulin
      cd00063
      Location:534626
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:316410
      fn3; Fibronectin type III domain
      cd00096
      Location:8997
      Ig; Ig strand B [structural motif]
      cl11960
      Location:88160
      Ig; Immunoglobulin domain

    RNA

    1. XR_004935499.1 RNA Sequence

    2. XR_001778946.2 RNA Sequence

    3. XR_379432.4 RNA Sequence