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    Bptf bromodomain PHD finger transcription factor [ Mus musculus (house mouse) ]

    Gene ID: 207165, updated on 9-Dec-2024

    Summary

    Official Symbol
    Bptfprovided by MGI
    Official Full Name
    bromodomain PHD finger transcription factorprovided by MGI
    Primary source
    MGI:MGI:2444008
    See related
    Ensembl:ENSMUSG00000040481 AllianceGenome:MGI:2444008
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Falz; 9430093H17Rik
    Summary
    Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and methylated histone binding activity. Predicted to contribute to ATP-dependent activity, acting on DNA. Acts upstream of or within anterior/posterior pattern specification; embryonic placenta development; and endoderm development. Predicted to be located in several cellular components, including cell body; dendrite; and perinuclear region of cytoplasm. Predicted to be part of NURF complex. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; and retina. Used to study neurodevelopmental disorder with dysmorphic facies and distal limb anomalies. Human ortholog(s) of this gene implicated in Kaposi's sarcoma; alcohol dependence; and neurodevelopmental disorder with dysmorphic facies and distal limb anomalies. Orthologous to human BPTF (bromodomain PHD finger transcription factor). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in thymus adult (RPKM 10.4), CNS E11.5 (RPKM 10.0) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Bptf in Genome Data Viewer
    Location:
    11 E1; 11 70.11 cM
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (106923907..107022982, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (107033081..107132147, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E4007 Neighboring gene STARR-seq mESC enhancer starr_30953 Neighboring gene RIKEN cDNA 1810010H24 gene Neighboring gene nuclear encoded tRNA arginine 1 (anticodon CCG) Neighboring gene STARR-positive B cell enhancer ABC_E9377 Neighboring gene STARR-positive B cell enhancer mm9_chr11:106905708-106906009 Neighboring gene STARR-positive B cell enhancer ABC_E2373 Neighboring gene STARR-positive B cell enhancer ABC_E5290 Neighboring gene STARR-positive B cell enhancer ABC_E10725 Neighboring gene STARR-seq mESC enhancer starr_30956 Neighboring gene STARR-positive B cell enhancer ABC_E10726 Neighboring gene STARR-seq mESC enhancer starr_30959 Neighboring gene STARR-seq mESC enhancer starr_30962 Neighboring gene predicted gene 11715 Neighboring gene nucleolar protein 11 Neighboring gene ribosomal protein S2 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC54978

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to ATP-dependent activity, acting on DNA ISO
    Inferred from Sequence Orthology
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables methylated histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of ATPase complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of NURF complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of NURF complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    nucleosome-remodeling factor subunit BPTF
    Names
    fetal Alzheimer antigen

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001359590.2NP_001346519.1  nucleosome-remodeling factor subunit BPTF isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL596116
      UniProtKB/TrEMBL
      E5D6T0
      Conserved Domains (8) summary
      cd05509
      Location:26732773
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      smart00571
      Location:252311
      DDT; domain in different transcription and chromosome remodeling factors
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:26112657
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam09606
      Location:19652386
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      cl25742
      Location:24062528
      ERM; Ezrin/radixin/moesin family
    2. NM_176850.3NP_789820.2  nucleosome-remodeling factor subunit BPTF isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL596116
      Consensus CDS
      CCDS48964.1
      UniProtKB/TrEMBL
      A2A655, E9Q6A7
      Related
      ENSMUSP00000052303.9, ENSMUST00000057892.15
      Conserved Domains (6) summary
      cd05509
      Location:28062906
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:27442790
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam02791
      Location:253309
      DDT; DDT domain
      pfam03955
      Location:20802169
      Adeno_PIX; Adenovirus hexon-associated protein (IX)
      pfam15612
      Location:351400
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      106923907..107022982 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006532690.3XP_006532753.1  nucleosome-remodeling factor subunit BPTF isoform X23

      UniProtKB/TrEMBL
      A2A654
      Conserved Domains (9) summary
      cd05509
      Location:27982898
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      COG5271
      Location:578749
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:27362782
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam02791
      Location:253309
      DDT; DDT domain
      pfam03157
      Location:21402518
      Glutenin_hmw; High molecular weight glutenin subunit
      pfam13868
      Location:25312653
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
    2. XM_036156484.1XP_036012377.1  nucleosome-remodeling factor subunit BPTF isoform X20

      UniProtKB/TrEMBL
      A2A654
      Conserved Domains (9) summary
      cd05509
      Location:28562956
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      smart00571
      Location:252311
      DDT; domain in different transcription and chromosome remodeling factors
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:27942840
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam03157
      Location:21402518
      Glutenin_hmw; High molecular weight glutenin subunit
      pfam13868
      Location:25312656
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      NF033845
      Location:579752
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
    3. XM_006532686.4XP_006532749.1  nucleosome-remodeling factor subunit BPTF isoform X12

      UniProtKB/TrEMBL
      A2A654
      Related
      ENSMUSP00000102374.2, ENSMUST00000106763.8
      Conserved Domains (9) summary
      cd05509
      Location:29313031
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      COG5271
      Location:578749
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:28692915
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam09606
      Location:21922555
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam02791
      Location:253309
      DDT; DDT domain
      pfam13868
      Location:26422782
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
    4. XM_017314399.3XP_017169888.1  nucleosome-remodeling factor subunit BPTF isoform X19

      UniProtKB/TrEMBL
      A2A654
      Conserved Domains (10) summary
      cd05509
      Location:28522952
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      COG5271
      Location:578749
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:27902836
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam02791
      Location:253309
      DDT; DDT domain
      pfam03157
      Location:21942572
      Glutenin_hmw; High molecular weight glutenin subunit
      pfam13868
      Location:25852707
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      pfam17823
      Location:20382345
      DUF5585; Family of unknown function (DUF5585)
    5. XM_030245733.2XP_030101593.1  nucleosome-remodeling factor subunit BPTF isoform X16

      UniProtKB/TrEMBL
      A2A654
      Conserved Domains (10) summary
      cd05509
      Location:29103010
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      COG5271
      Location:578749
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:28482894
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam02791
      Location:253309
      DDT; DDT domain
      pfam03157
      Location:21942572
      Glutenin_hmw; High molecular weight glutenin subunit
      pfam13868
      Location:25852707
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      pfam17823
      Location:20382345
      DUF5585; Family of unknown function (DUF5585)
    6. XM_006532685.2XP_006532748.1  nucleosome-remodeling factor subunit BPTF isoform X11

      UniProtKB/TrEMBL
      A2A654
      Conserved Domains (10) summary
      COG5271
      Location:578749
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:29232969
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam09606
      Location:22462609
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam02791
      Location:253309
      DDT; DDT domain
      pfam13868
      Location:26962836
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      pfam17823
      Location:20382345
      DUF5585; Family of unknown function (DUF5585)
      cl02556
      Location:29853030
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    7. XM_006532680.2XP_006532743.1  nucleosome-remodeling factor subunit BPTF isoform X6

      UniProtKB/TrEMBL
      A2A654
      Conserved Domains (10) summary
      cd05509
      Location:29853085
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      COG5271
      Location:578749
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:29232969
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam09606
      Location:22462609
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam02791
      Location:253309
      DDT; DDT domain
      pfam13868
      Location:26962836
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      pfam17823
      Location:20382345
      DUF5585; Family of unknown function (DUF5585)
    8. XM_006532684.4XP_006532747.1  nucleosome-remodeling factor subunit BPTF isoform X10

      UniProtKB/TrEMBL
      A2A654
      Conserved Domains (10) summary
      cd05509
      Location:29853085
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      COG5271
      Location:578749
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:29232969
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam09606
      Location:22462609
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam02791
      Location:253309
      DDT; DDT domain
      pfam13868
      Location:26962836
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      pfam17823
      Location:20382345
      DUF5585; Family of unknown function (DUF5585)
    9. XM_006532678.2XP_006532741.1  nucleosome-remodeling factor subunit BPTF isoform X4

      UniProtKB/TrEMBL
      A2A654
      Conserved Domains (10) summary
      COG5271
      Location:578749
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:29813027
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam09606
      Location:22462609
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam02791
      Location:253309
      DDT; DDT domain
      pfam13868
      Location:26962836
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      pfam17823
      Location:20382345
      DUF5585; Family of unknown function (DUF5585)
      cl02556
      Location:30433088
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    10. XM_006532675.2XP_006532738.1  nucleosome-remodeling factor subunit BPTF isoform X1

      See identical proteins and their annotated locations for XP_006532738.1

      UniProtKB/TrEMBL
      A2A654
      Conserved Domains (10) summary
      cd05509
      Location:30433143
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      COG5271
      Location:578749
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:29813027
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam09606
      Location:22462609
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam02791
      Location:253309
      DDT; DDT domain
      pfam13868
      Location:26962836
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      pfam17823
      Location:20382345
      DUF5585; Family of unknown function (DUF5585)
    11. XM_006532677.4XP_006532740.1  nucleosome-remodeling factor subunit BPTF isoform X3

      UniProtKB/TrEMBL
      A2A654
      Conserved Domains (10) summary
      cd05509
      Location:30433143
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      COG5271
      Location:578749
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:29813027
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam09606
      Location:22462609
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam02791
      Location:253309
      DDT; DDT domain
      pfam13868
      Location:26962836
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      pfam17823
      Location:20382345
      DUF5585; Family of unknown function (DUF5585)
    12. XM_006532687.3XP_006532750.1  nucleosome-remodeling factor subunit BPTF isoform X14

      UniProtKB/TrEMBL
      A2A655
      Conserved Domains (9) summary
      cd05509
      Location:29183018
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:28562902
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam09606
      Location:21212484
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam02791
      Location:253309
      DDT; DDT domain
      pfam13868
      Location:25712711
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      pfam17823
      Location:19132220
      DUF5585; Family of unknown function (DUF5585)
    13. XM_006532683.3XP_006532746.1  nucleosome-remodeling factor subunit BPTF isoform X9

      UniProtKB/TrEMBL
      A2A655
      Conserved Domains (10) summary
      cd05509
      Location:29793079
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:29172963
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam09606
      Location:21822545
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam02791
      Location:253309
      DDT; DDT domain
      pfam13868
      Location:26322772
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      pfam17823
      Location:19742281
      DUF5585; Family of unknown function (DUF5585)
      NF000535
      Location:519653
      MSCRAMM_SdrC; MSCRAMM family adhesin SdrC
    14. XM_006532682.3XP_006532745.1  nucleosome-remodeling factor subunit BPTF isoform X8

      UniProtKB/TrEMBL
      A2A655
      Conserved Domains (10) summary
      cd05509
      Location:29803080
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:29182964
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam09606
      Location:21832546
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam02791
      Location:253309
      DDT; DDT domain
      pfam13868
      Location:26332773
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      pfam17823
      Location:19752282
      DUF5585; Family of unknown function (DUF5585)
      NF000535
      Location:519687
      MSCRAMM_SdrC; MSCRAMM family adhesin SdrC
    15. XM_006532681.3XP_006532744.1  nucleosome-remodeling factor subunit BPTF isoform X7

      UniProtKB/TrEMBL
      A2A655
      Conserved Domains (9) summary
      cd05509
      Location:29813081
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:29192965
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam09606
      Location:21842547
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam02791
      Location:253309
      DDT; DDT domain
      pfam13868
      Location:26342774
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      pfam17823
      Location:19762283
      DUF5585; Family of unknown function (DUF5585)
    16. XM_006532676.3XP_006532739.1  nucleosome-remodeling factor subunit BPTF isoform X2

      UniProtKB/TrEMBL
      A2A654
      Conserved Domains (10) summary
      cd05509
      Location:30423142
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      COG5271
      Location:578748
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:29803026
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam09606
      Location:22452608
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam02791
      Location:253309
      DDT; DDT domain
      pfam13868
      Location:26952835
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      pfam17823
      Location:20372344
      DUF5585; Family of unknown function (DUF5585)
    17. XM_006532679.3XP_006532742.1  nucleosome-remodeling factor subunit BPTF isoform X5

      UniProtKB/TrEMBL
      A2A654
      Conserved Domains (9) summary
      cd05509
      Location:29893089
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      COG5271
      Location:578749
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:29272973
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam09606
      Location:21922555
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam02791
      Location:253309
      DDT; DDT domain
      pfam13868
      Location:26422782
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
    18. XM_036156488.1XP_036012381.1  nucleosome-remodeling factor subunit BPTF isoform X26

      UniProtKB/TrEMBL
      E5D6T0
      Conserved Domains (8) summary
      cd05509
      Location:27312831
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      smart00571
      Location:252311
      DDT; domain in different transcription and chromosome remodeling factors
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:26692715
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam03157
      Location:20152393
      Glutenin_hmw; High molecular weight glutenin subunit
      pfam13868
      Location:24062531
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
    19. XM_036156486.1XP_036012379.1  nucleosome-remodeling factor subunit BPTF isoform X24

      UniProtKB/TrEMBL
      A2A654
      Conserved Domains (8) summary
      cd05509
      Location:27942894
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      smart00571
      Location:252311
      DDT; domain in different transcription and chromosome remodeling factors
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:27322778
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam03157
      Location:20782456
      Glutenin_hmw; High molecular weight glutenin subunit
      pfam13868
      Location:24692594
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
    20. XM_006532689.3XP_006532752.1  nucleosome-remodeling factor subunit BPTF isoform X18

      UniProtKB/TrEMBL
      A2A654
      Conserved Domains (9) summary
      cd05509
      Location:28562956
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      COG5271
      Location:578749
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:27942840
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam02791
      Location:253309
      DDT; DDT domain
      pfam03157
      Location:21402518
      Glutenin_hmw; High molecular weight glutenin subunit
      pfam13868
      Location:25312653
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
    21. XM_006532688.3XP_006532751.1  nucleosome-remodeling factor subunit BPTF isoform X15

      UniProtKB/TrEMBL
      A2A654
      Conserved Domains (10) summary
      cd05509
      Location:29103010
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      COG5271
      Location:578749
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:28482894
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam02791
      Location:253309
      DDT; DDT domain
      pfam03157
      Location:21942572
      Glutenin_hmw; High molecular weight glutenin subunit
      pfam13868
      Location:25852707
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      pfam17823
      Location:20382345
      DUF5585; Family of unknown function (DUF5585)
    22. XM_030245735.2XP_030101595.1  nucleosome-remodeling factor subunit BPTF isoform X22

      UniProtKB/TrEMBL
      A2A654
      Conserved Domains (10) summary
      COG5271
      Location:578749
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:27902836
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam02791
      Location:253309
      DDT; DDT domain
      pfam03157
      Location:21942572
      Glutenin_hmw; High molecular weight glutenin subunit
      pfam13868
      Location:25852707
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      pfam17823
      Location:20382345
      DUF5585; Family of unknown function (DUF5585)
      cl02556
      Location:28522897
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    23. XM_036156483.1XP_036012376.1  nucleosome-remodeling factor subunit BPTF isoform X17

      UniProtKB/TrEMBL
      A2A654
      Conserved Domains (9) summary
      smart00571
      Location:252311
      DDT; domain in different transcription and chromosome remodeling factors
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:28482894
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam03157
      Location:21942572
      Glutenin_hmw; High molecular weight glutenin subunit
      pfam13868
      Location:25852710
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      NF033845
      Location:579752
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
      cl02556
      Location:29102955
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    24. XM_036156487.1XP_036012380.1  nucleosome-remodeling factor subunit BPTF isoform X25

      UniProtKB/TrEMBL
      A2A654
      Conserved Domains (9) summary
      cd05509
      Location:27982898
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      smart00571
      Location:252311
      DDT; domain in different transcription and chromosome remodeling factors
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:27362782
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam03157
      Location:21402518
      Glutenin_hmw; High molecular weight glutenin subunit
      pfam13868
      Location:25312656
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      NF033845
      Location:579752
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
    25. XM_036156485.1XP_036012378.1  nucleosome-remodeling factor subunit BPTF isoform X21

      UniProtKB/TrEMBL
      A2A654
      Conserved Domains (9) summary
      smart00571
      Location:252311
      DDT; domain in different transcription and chromosome remodeling factors
      COG5271
      Location:578749
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:27942840
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam03157
      Location:21402518
      Glutenin_hmw; High molecular weight glutenin subunit
      pfam13868
      Location:25312656
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      cl02556
      Location:28562901
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    26. XM_036156482.1XP_036012375.1  nucleosome-remodeling factor subunit BPTF isoform X13

      UniProtKB/TrEMBL
      A2A654
      Conserved Domains (9) summary
      cd05509
      Location:29313031
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      smart00571
      Location:252311
      DDT; domain in different transcription and chromosome remodeling factors
      COG5271
      Location:578749
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      cd15559
      Location:404446
      PHD1_BPTF; PHD finger 1 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      cd15560
      Location:28692915
      PHD2_3_BPTF; PHD finger 2 and 3 found in bromodomain and PHD finger-containing transcription factor (BPTF)
      pfam03157
      Location:21402518
      Glutenin_hmw; High molecular weight glutenin subunit
      pfam13868
      Location:26432789
      TPH; Trichohyalin-plectin-homology domain
      pfam15612
      Location:356393
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:468536
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001080832.1: Suppressed sequence

      Description
      NM_001080832.1: This RefSeq was temporarily suppressed because currently there is not sufficient data to support this transcript.