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    Lrrc72 leucine rich repeat containing 72 [ Mus musculus (house mouse) ]

    Gene ID: 71156, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lrrc72provided by MGI
    Official Full Name
    leucine rich repeat containing 72provided by MGI
    Primary source
    MGI:MGI:1920830
    See related
    Ensembl:ENSMUSG00000020545 AllianceGenome:MGI:1920830
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700108M19Rik; 4933421E18Rik
    Summary
    Orthologous to human LRRC72 (leucine rich repeat containing 72). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 4.3) See more
    Orthologs
    human all
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    Genomic context

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    See Lrrc72 in Genome Data Viewer
    Location:
    12 A3; 12 16.63 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (36258328..36306395, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (36208329..36256396, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene basic leucine zipper and W2 domains 2 Neighboring gene ribosomal protein S3A pseudogene Neighboring gene STARR-seq mESC enhancer starr_31915 Neighboring gene STARR-positive B cell enhancer ABC_E1153 Neighboring gene ankyrin repeat and MYND domain containing 2 Neighboring gene non-POU-domain-containing, octamer binding protein pseudogene Neighboring gene STARR-seq mESC enhancer starr_31916 Neighboring gene predicted gene, 40390 Neighboring gene STARR-seq mESC enhancer starr_31918 Neighboring gene predicted gene, 40392 Neighboring gene STARR-seq mESC enhancer starr_31919 Neighboring gene sclerostin domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression. West DB, et al. PLoS Genet, 2016 Feb. PMID 26839965, Free PMC Article
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC130241, MGC130242

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 72

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001361098.1 → NP_001348027.1  leucine-rich repeat-containing protein 72 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC124776
      Consensus CDS
      CCDS88328.1
      UniProtKB/TrEMBL
      A0A1Y7VMI0
      Related
      ENSMUSP00000152732.2, ENSMUST00000221155.2
      Conserved Domains (3) summary
      COG4886
      Location:16 → 128
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00031
      Location:50 → 69
      LRR_1; leucine-rich repeat [structural motif]
      pfam14580
      Location:79 → 191
      LRR_9; Leucine-rich repeat

    2. NM_027699.3 → NP_081975.1  leucine-rich repeat-containing protein 72 isoform 1

      See identical proteins and their annotated locations for NP_081975.1

      Status: VALIDATED

      Source sequence(s)
      AC124776, AK007140, AK077182
      Consensus CDS
      CCDS25886.1
      UniProtKB/TrEMBL
      Q9D9C3
      Related
      ENSMUSP00000020853.2, ENSMUST00000020853.8

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      36258328..36306395 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006515213.2 → XP_006515276.1  leucine-rich repeat-containing protein 72 isoform X1

      UniProtKB/TrEMBL
      A0A1Y7VMI0
      Conserved Domains (3) summary
      COG4886
      Location:16 → 128
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00031
      Location:50 → 69
      LRR_1; leucine-rich repeat [structural motif]
      pfam14580
      Location:79 → 191
      LRR_9; Leucine-rich repeat

    2. XM_030246923.1 → XP_030102783.1  leucine-rich repeat-containing protein 72 isoform X3

      UniProtKB/TrEMBL
      Q9D9C3

    3. XM_030246922.1 → XP_030102782.1  leucine-rich repeat-containing protein 72 isoform X3

      UniProtKB/TrEMBL
      Q9D9C3

    4. XM_030246921.1 → XP_030102781.1  leucine-rich repeat-containing protein 72 isoform X3

      UniProtKB/TrEMBL
      Q9D9C3

    5. XM_017315204.2 → XP_017170693.1  leucine-rich repeat-containing protein 72 isoform X2

      Conserved Domains (2) summary
      sd00031
      Location:50 → 69
      LRR_1; leucine-rich repeat [structural motif]
      pfam14580
      Location:79 → 171
      LRR_9; Leucine-rich repeat

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001177877.1: Suppressed sequence

      Description
      NM_001177877.1: This RefSeq was removed because currently there is insufficient support for the transcript and protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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