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    ZMYND11 zinc finger MYND-type containing 11 [ Homo sapiens (human) ]

    Gene ID: 10771, updated on 27-Nov-2024

    Summary

    Official Symbol
    ZMYND11provided by HGNC
    Official Full Name
    zinc finger MYND-type containing 11provided by HGNC
    Primary source
    HGNC:HGNC:16966
    See related
    Ensembl:ENSG00000015171 MIM:608668; AllianceGenome:HGNC:16966
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    BS69; BRAM1; MRD30
    Summary
    The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
    Expression
    Ubiquitous expression in thyroid (RPKM 38.3), brain (RPKM 25.5) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ZMYND11 in Genome Data Viewer
    Location:
    10p15.3
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (130088..254637)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (122992..247610)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (176028..300577)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene ReSE screen-validated silencer GRCh37_chr10:93160-93307 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2890 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2057 Neighboring gene tubulin beta 8 class VIII Neighboring gene IL9R pseudogene 2 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:180644-180822 Neighboring gene Sharpr-MPRA regulatory region 15592 Neighboring gene RNA, 5S ribosomal pseudogene 297 Neighboring gene DEAD-box helicase 20 pseudogene 1 Neighboring gene uncharacterized LOC107984190 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr10:294268-295467 Neighboring gene uncharacterized LOC107984191 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:310208-311407 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr10:315279-315788 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr10:315789-316297 Neighboring gene RNA, 5S ribosomal pseudogene 298 Neighboring gene disco interacting protein 2 homolog C

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    Associated conditions

    Description Tests
    Intellectual disability, autosomal dominant 30
    MedGen: C4015167 OMIM: 616083 GeneReviews: Not available
    Compare labs

    Copy number response

    Description
    Copy number response
    Triplosensitivity

    No evidence available (Last evaluated 2018-03-28)

    ClinGen Genome Curation PagePubMed
    Haploinsufficency

    Sufficient evidence for dosage pathogenicity (Last evaluated 2018-03-28)

    ClinGen Genome Curation PagePubMed

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC111056

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables double-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables methylated histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables methylated histone binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables methylated histone binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transcription corepressor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables zinc ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables zinc ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    zinc finger MYND domain-containing protein 11
    Names
    adenovirus 5 E1A-binding protein
    bone morphogenetic protein receptor-associated molecule 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_029960.1 RefSeqGene

      Range
      5991..125173
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001202464.3NP_001189393.1  zinc finger MYND domain-containing protein 11 isoform c

      See identical proteins and their annotated locations for NP_001189393.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4), as well as variants 16-22, encodes isoform c.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS73060.1
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000385484.1, ENST00000403354.5
      Conserved Domains (3) summary
      cd05841
      Location:218299
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104204
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:509544
      zf-MYND; MYND finger
    2. NM_001202465.3NP_001189394.1  zinc finger MYND domain-containing protein 11 isoform d

      See identical proteins and their annotated locations for NP_001189394.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5), as well as variant 23, encodes isoform d.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS55697.1
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (3) summary
      cd05841
      Location:187268
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      pfam01753
      Location:478513
      zf-MYND; MYND finger
      cl02556
      Location:95173
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    3. NM_001202466.3NP_001189395.1  zinc finger MYND domain-containing protein 11 isoform e

      See identical proteins and their annotated locations for NP_001189395.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6), as well as variant 24, encodes isoform e.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      UniProtKB/TrEMBL
      B7Z2J6, B7Z3W2
      Conserved Domains (3) summary
      cd05841
      Location:217298
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104203
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:508543
      zf-MYND; MYND finger
    4. NM_001202467.1NP_001189396.1  zinc finger MYND domain-containing protein 11 isoform f

      See identical proteins and their annotated locations for NP_001189396.1

      Status: REVIEWED

      Source sequence(s)
      AI244299, AL589988, BC034784, DB521520, DQ335454
      Consensus CDS
      CCDS91197.1
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000515849.1, ENST00000704335.1
      Conserved Domains (2) summary
      cd05841
      Location:218299
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104204
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    5. NM_001202468.1NP_001189397.1  zinc finger MYND domain-containing protein 11 isoform g

      See identical proteins and their annotated locations for NP_001189397.1

      Status: REVIEWED

      Source sequence(s)
      AI244299, AL589988, BC034784, DB521520, DQ335455
      Consensus CDS
      CCDS55696.1
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000452959.1, ENST00000558098.4
      Conserved Domains (3) summary
      cd05841
      Location:272353
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158258
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102145
      PHD_BS69; PHD finger found in protein BS69
    6. NM_001330057.3NP_001316986.1  zinc finger MYND domain-containing protein 11 isoform h precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9), as well as variant 25, encodes isoform h.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (4) summary
      cd05841
      Location:255336
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:141241
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:85128
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:546581
      zf-MYND; MYND finger
    7. NM_001370097.3NP_001357026.1  zinc finger MYND domain-containing protein 11 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10), as well as variants 1 and 11-15, encodes the longest isoform (a).
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS7052.2
      UniProtKB/Swiss-Prot
      B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (4) summary
      cd05841
      Location:272353
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158258
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102145
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:563598
      zf-MYND; MYND finger
    8. NM_001370098.2NP_001357027.1  zinc finger MYND domain-containing protein 11 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11), as well as variants 1, 10, and 12-15, encodes the longest isoform (a).
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS7052.2
      UniProtKB/Swiss-Prot
      B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (4) summary
      cd05841
      Location:272353
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158258
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102145
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:563598
      zf-MYND; MYND finger
    9. NM_001370099.2NP_001357028.1  zinc finger MYND domain-containing protein 11 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12), as well as variants 1, 10, 11, and 13-15, encodes the longest isoform (a).
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS7052.2
      UniProtKB/Swiss-Prot
      B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000371003.1, ENST00000381591.5
      Conserved Domains (4) summary
      cd05841
      Location:272353
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158258
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102145
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:563598
      zf-MYND; MYND finger
    10. NM_001370100.5NP_001357029.1  zinc finger MYND domain-containing protein 11 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (13), as well as variants 1, 10-12, 14, and 15, encodes the longest isoform (a).
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS7052.2
      UniProtKB/Swiss-Prot
      B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000371017.6, ENST00000381604.9
      Conserved Domains (4) summary
      cd05841
      Location:272353
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158258
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102145
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:563598
      zf-MYND; MYND finger
    11. NM_001370101.2NP_001357030.1  zinc finger MYND domain-containing protein 11 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (14), as well as variants 1, 10-13, and 15, encodes the longest isoform (a).
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS7052.2
      UniProtKB/Swiss-Prot
      B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (4) summary
      cd05841
      Location:272353
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158258
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102145
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:563598
      zf-MYND; MYND finger
    12. NM_001370102.2NP_001357031.1  zinc finger MYND domain-containing protein 11 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (15), as well as variants 1 and 10-14, encodes the longest isoform (a).
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS7052.2
      UniProtKB/Swiss-Prot
      B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000515825.1, ENST00000704301.1
      Conserved Domains (4) summary
      cd05841
      Location:272353
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158258
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102145
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:563598
      zf-MYND; MYND finger
    13. NM_001370103.2NP_001357032.1  zinc finger MYND domain-containing protein 11 isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (16), as well as variants 4 and 17-22, encodes isoform c.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS73060.1
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000515819.1, ENST00000704295.1
      Conserved Domains (3) summary
      cd05841
      Location:218299
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104204
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:509544
      zf-MYND; MYND finger
    14. NM_001370104.2NP_001357033.1  zinc finger MYND domain-containing protein 11 isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (17), as well as variants 4, 16, and 18-22, encodes isoform c.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS73060.1
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (3) summary
      cd05841
      Location:218299
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104204
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:509544
      zf-MYND; MYND finger
    15. NM_001370105.2NP_001357034.1  zinc finger MYND domain-containing protein 11 isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (18), as well as variants 4, 16, 17, and 19-22, encodes isoform c.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS73060.1
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (3) summary
      cd05841
      Location:218299
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104204
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:509544
      zf-MYND; MYND finger
    16. NM_001370106.2NP_001357035.1  zinc finger MYND domain-containing protein 11 isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (19), as well as variants 4, 16-18, and 20-22, encodes isoform c.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS73060.1
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (3) summary
      cd05841
      Location:218299
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104204
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:509544
      zf-MYND; MYND finger
    17. NM_001370107.2NP_001357036.1  zinc finger MYND domain-containing protein 11 isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (20), as well as variants 4, 16-19, 21, and 22, encodes isoform c.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS73060.1
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (3) summary
      cd05841
      Location:218299
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104204
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:509544
      zf-MYND; MYND finger
    18. NM_001370108.2NP_001357037.1  zinc finger MYND domain-containing protein 11 isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (21), as well as variants 4, 16-20, and 22, encodes isoform c.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS73060.1
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (3) summary
      cd05841
      Location:218299
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104204
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:509544
      zf-MYND; MYND finger
    19. NM_001370109.2NP_001357038.1  zinc finger MYND domain-containing protein 11 isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (22), as well as variants 4 and 16-21, encodes isoform c.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS73060.1
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000515827.1, ENST00000704303.1
      Conserved Domains (3) summary
      cd05841
      Location:218299
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104204
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:509544
      zf-MYND; MYND finger
    20. NM_001370110.2NP_001357039.1  zinc finger MYND domain-containing protein 11 isoform d

      Status: REVIEWED

      Description
      Transcript Variant: This variant (23), as well as variant 5, encodes isoform d.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS55697.1
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000473321.1, ENST00000602682.6
      Conserved Domains (3) summary
      cd05841
      Location:187268
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      pfam01753
      Location:478513
      zf-MYND; MYND finger
      cl02556
      Location:95173
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    21. NM_001370111.2NP_001357040.1  zinc finger MYND domain-containing protein 11 isoform e

      Status: REVIEWED

      Description
      Transcript Variant: This variant (24), as well as variant 6, encodes isoform e.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      UniProtKB/TrEMBL
      B7Z2J6, B7Z3W2
      Conserved Domains (3) summary
      cd05841
      Location:217298
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104203
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:508543
      zf-MYND; MYND finger
    22. NM_001370112.2NP_001357041.1  zinc finger MYND domain-containing protein 11 isoform h precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (25), as well as variant 9, encodes isoform h.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (4) summary
      cd05841
      Location:255336
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:141241
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:85128
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:546581
      zf-MYND; MYND finger
    23. NM_001370113.2NP_001357042.1  zinc finger MYND domain-containing protein 11 isoform i

      Status: REVIEWED

      Description
      Transcript Variant: This variant (26), as well as variant 27, encodes isoform i.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS91196.1
      UniProtKB/TrEMBL
      B7Z3W2, E7ENI9
      Conserved Domains (3) summary
      cd05841
      Location:241322
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      pfam01753
      Location:532567
      zf-MYND; MYND finger
      cl02556
      Location:113227
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    24. NM_001370114.2NP_001357043.1  zinc finger MYND domain-containing protein 11 isoform i

      Status: REVIEWED

      Description
      Transcript Variant: This variant (27), as well as variant 6, encodes isoform i.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS91196.1
      UniProtKB/TrEMBL
      B7Z3W2, E7ENI9
      Related
      ENSP00000386010.1, ENST00000402736.5
      Conserved Domains (3) summary
      cd05841
      Location:241322
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      pfam01753
      Location:532567
      zf-MYND; MYND finger
      cl02556
      Location:113227
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    25. NM_001370115.2NP_001357044.1  zinc finger MYND domain-containing protein 11 isoform j

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS91195.1
      UniProtKB/TrEMBL
      A0A0D9SGD6, B7Z3W2
      Related
      ENSP00000487386.2, ENST00000627286.2
      Conserved Domains (4) summary
      cd05841
      Location:271352
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158257
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102145
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:562597
      zf-MYND; MYND finger
    26. NM_001370116.2NP_001357045.1  zinc finger MYND domain-containing protein 11 isoform k

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (4) summary
      cd05841
      Location:250331
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:136236
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:80123
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:541576
      zf-MYND; MYND finger
    27. NM_001370117.2NP_001357046.1  zinc finger MYND domain-containing protein 11 isoform l

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS91194.1
      UniProtKB/TrEMBL
      A0A994J6Y5, B7Z3W2
      Related
      ENSP00000515835.1, ENST00000704315.1
      Conserved Domains (4) summary
      cd05841
      Location:272353
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158258
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102145
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:540575
      zf-MYND; MYND finger
    28. NM_001370118.2NP_001357047.1  zinc finger MYND domain-containing protein 11 isoform m

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922
      Consensus CDS
      CCDS91199.1
      UniProtKB/TrEMBL
      A0A994J4C0, B7Z3W2
      Related
      ENSP00000515854.1, ENST00000704343.1
      Conserved Domains (4) summary
      cd05841
      Location:232313
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:118218
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:62105
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:523558
      zf-MYND; MYND finger
    29. NM_001370119.2NP_001357048.1  zinc finger MYND domain-containing protein 11 isoform n

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      UniProtKB/TrEMBL
      A0A0A0MRY2
      Conserved Domains (4) summary
      cd05841
      Location:252327
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158252
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102145
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:514549
      zf-MYND; MYND finger
    30. NM_001370120.2NP_001357049.1  zinc finger MYND domain-containing protein 11 isoform o

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (3) summary
      cd05841
      Location:196277
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:82182
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:487522
      zf-MYND; MYND finger
    31. NM_001370121.2NP_001357050.1  zinc finger MYND domain-containing protein 11 isoform p

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922
      UniProtKB/TrEMBL
      B7Z3W2, Q5BJG6
      Conserved Domains (3) summary
      cd05841
      Location:178259
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:64164
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:469504
      zf-MYND; MYND finger
    32. NM_001370122.2NP_001357051.1  zinc finger MYND domain-containing protein 11 isoform q

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS91198.1
      UniProtKB/TrEMBL
      A0A994J4I8, A0A994J4J2
      Related
      ENSP00000515831.1, ENST00000704307.1
      Conserved Domains (3) summary
      cd05841
      Location:170251
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      pfam01753
      Location:461496
      zf-MYND; MYND finger
      cl02556
      Location:104149
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    33. NM_001370123.2NP_001357052.1  zinc finger MYND domain-containing protein 11 isoform r precursor

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      UniProtKB/TrEMBL
      A0A0A0MRY2, Q5UGI2
      Conserved Domains (3) summary
      cd05841
      Location:153234
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      pfam01753
      Location:444479
      zf-MYND; MYND finger
      cl02556
      Location:87132
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    34. NM_001370124.3NP_001357053.1  zinc finger MYND domain-containing protein 11 isoform s

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922
      UniProtKB/TrEMBL
      B7Z3Z1
      Conserved Domains (3) summary
      cd05841
      Location:115196
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:1101
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:406441
      zf-MYND; MYND finger
    35. NM_006624.7NP_006615.2  zinc finger MYND domain-containing protein 11 isoform a

      See identical proteins and their annotated locations for NP_006615.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1), as well as variants 10-15, encodes the longest isoform (a).
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS7052.2
      UniProtKB/Swiss-Prot
      B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000381053.3, ENST00000397962.8
      Conserved Domains (4) summary
      cd05841
      Location:272353
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158258
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102145
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:563598
      zf-MYND; MYND finger
    36. NM_212479.4NP_997644.2  zinc finger MYND domain-containing protein 11 isoform b

      See identical proteins and their annotated locations for NP_997644.2

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL713922, AL731539
      Consensus CDS
      CCDS7053.2
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000424205.2, ENST00000509513.6
      Conserved Domains (3) summary
      cd05841
      Location:271352
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158257
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102145
      PHD_BS69; PHD finger found in protein BS69

    RNA

    1. NR_163254.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Related
      ENST00000381584.6

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      130088..254637
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017015594.2XP_016871083.1  zinc finger MYND domain-containing protein 11 isoform X1

      UniProtKB/TrEMBL
      B7Z3W2

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      122992..247610
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054364630.1XP_054220605.1  zinc finger MYND domain-containing protein 11 isoform X1