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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_029218.1 RefSeqGene
- Range
-
4876..122092
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_000872.5 → NP_000863.1 5-hydroxytryptamine receptor 7 isoform a
Status: REVIEWED
- Description
- Transcript Variant: This variant (a) results from the alternative usage of the first of two tandemly arranged splice donor sites at the 5' end of intron 2, which causes the protein to have a 13 amino acid longer carboxy tail relative to isoform b.
- Source sequence(s)
-
AL360011, BC047526, BG108256
- Consensus CDS
-
CCDS7409.1
- UniProtKB/Swiss-Prot
-
P34969
- Related
- ENSP00000277874.6, ENST00000277874.10
- Conserved Domains (1) summary
-
- cd15329
Location:97 → 395
- 7tmA_5-HT7; serotonin receptor subtype 7, member of the class A family of seven-transmembrane G protein-coupled receptors
-
NM_019859.4 → NP_062873.1 5-hydroxytryptamine receptor 7 isoform d
Status: REVIEWED
- Description
- Transcript Variant: This variant (d) results from the inclusion of a 98 base pair exon cassette (exon D) at the exon II/exon III boundary, as compared to splice variant a. The inclusion of exon D results in a protein with a carboxy terminal end 34 amino acids longer than the splice variant a protein.
- Source sequence(s)
-
AL360011, BC047526, BG108256, U68488
- Consensus CDS
-
CCDS7408.1
- UniProtKB/Swiss-Prot
- B5BUP6, P34969, P78336, P78372, P78516, Q5VX01, Q5VX02, Q5VX03
- Related
- ENSP00000337949.3, ENST00000336152.8
- Conserved Domains (2) summary
-
- pfam00001
Location:98 → 384
- 7tm_1; 7 transmembrane receptor (rhodopsin family)
- cl21561
Location:98 → 215
- 7tm_4; Olfactory receptor
-
NM_019860.4 → NP_062874.1 5-hydroxytryptamine receptor 7 isoform b
Status: REVIEWED
- Description
- Transcript Variant: This variant (b) results from the alternative usage of the second of the two tandemly arranged splice donor sites at the 5' end of intron 2, which causes an in-frame stop codon and shortens the protein's carboxy tail by 13 amino acids relative to isoform a.
- Source sequence(s)
-
AL360011, BC047526, BG108256, U68487
- Consensus CDS
-
CCDS7410.1
- UniProtKB/Swiss-Prot
-
P34969
- Related
- ENSP00000360784.2, ENST00000371719.2
- Conserved Domains (1) summary
-
- cd15329
Location:97 → 395
- 7tmA_5-HT7; serotonin receptor subtype 7, member of the class A family of seven-transmembrane G protein-coupled receptors
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000010.11 Reference GRCh38.p14 Primary Assembly
- Range
-
90740823..90858039 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_024447973.2 → XP_024303741.1 5-hydroxytryptamine receptor 7 isoform X1
- Conserved Domains (2) summary
-
- cd15329
Location:3 → 19
- 7tmA_5-HT7; TM helix 4 [structural motif]
- cl28897
Location:1 → 197
- 7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
Alternate T2T-CHM13v2.0
Genomic
-
NC_060934.1 Alternate T2T-CHM13v2.0
- Range
-
91624488..91741713 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054365712.1 → XP_054221687.1 5-hydroxytryptamine receptor 7 isoform X1