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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001267556.2 → NP_001254485.1 programmed cell death protein 6 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate splice site in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
- Source sequence(s)
-
AK223366, BC012384, BC110291
- Consensus CDS
-
CCDS58940.1
- UniProtKB/TrEMBL
-
Q53FC3
- Related
- ENSP00000423815.1, ENST00000507528.5
- Conserved Domains (1) summary
-
- cd16183
Location:27 → 189
- EFh_PEF_ALG-2; EF-hand, calcium binding motif, found in apoptosis-linked gene 2 protein (ALG-2) and similar proteins
-
NM_001267557.2 → NP_001254486.1 programmed cell death protein 6 isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks two consecutive exons in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
- Source sequence(s)
-
AK223366, BC012384, BG390506
- Consensus CDS
-
CCDS75222.1
- UniProtKB/TrEMBL
-
A0A087WZ38
- Related
- ENSP00000482332.1, ENST00000618970.4
- Conserved Domains (2) summary
-
- cd15897
Location:27 → 54
- EFh_PEF; EF-hand motif [structural motif]
- cl25352
Location:27 → 123
- EFh_PEF; The penta-EF hand (PEF) family
-
NM_001267558.2 → NP_001254487.1 programmed cell death protein 6 isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) differs in the 5' UTR and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (4) has a shorter N-terminus, compared to isoform 1.
- Source sequence(s)
-
BC012384, DB495449
- Consensus CDS
-
CCDS75223.1
- UniProtKB/TrEMBL
-
A0A024QZ42
- Related
- ENSP00000485024.1, ENST00000614778.4
- Conserved Domains (2) summary
-
- cd15897
Location:24 → 54
- EFh_PEF; EF-hand motif [structural motif]
- cl25352
Location:1 → 121
- EFh_PEF; The penta-EF hand (PEF) family
-
NM_001267559.2 → NP_001254488.1 programmed cell death protein 6 isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks two consecutive exons in the coding region, which results in a frameshift, compared to variant 1. The encoded isoform (5) is shorter and has a distinct C-terminus, compared to isoform 1.
- Source sequence(s)
-
AK223366, BC012384, CR983268
- Consensus CDS
-
CCDS58941.1
- UniProtKB/TrEMBL
-
A0A6Q8PH81
- Related
- ENSP00000422085.1, ENST00000505221.5
- Conserved Domains (2) summary
-
- cd15897
Location:27 → 56
- EFh_PEF; EF-hand motif [structural motif]
- cl25352
Location:27 → 69
- EFh_PEF; The penta-EF hand (PEF) family
-
NM_013232.4 → NP_037364.1 programmed cell death protein 6 isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AK223366, BC012384
- Consensus CDS
-
CCDS3854.1
- UniProtKB/Swiss-Prot
- B2RD16, E7ESR3, O75340, Q2YDC2, Q5TZS0
- UniProtKB/TrEMBL
-
Q53FC3
- Related
- ENSP00000264933.4, ENST00000264933.9
- Conserved Domains (1) summary
-
- cd16183
Location:27 → 191
- EFh_PEF_ALG-2; EF-hand, calcium binding motif, found in apoptosis-linked gene 2 protein (ALG-2) and similar proteins
RNA
-
NR_073609.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) lacks several exons and includes an alternate 3' terminal exon, compared to variant 1. This variant (6) is represented as non-coding because the predicted ORF does not meet quality criteria for a protein coding locus with longer protein data.
- Source sequence(s)
-
AK223366, AW300963, BC050597
- Related
-
ENST00000509581.5
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000005.10 Reference GRCh38.p14 Primary Assembly
- Range
-
271646..314974
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060929.1 Alternate T2T-CHM13v2.0
- Range
-
261673..305205
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)