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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001291824.2 → NP_001278753.1 GRB2-related adapter protein 2 isoform 1
See identical proteins and their annotated locations for NP_001278753.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1). Variants 1, 2 and 3 encode the same isoform.
- Source sequence(s)
-
AK312830, DC409651, KF457461, Z82206
- Consensus CDS
-
CCDS13999.1
- UniProtKB/Swiss-Prot
- B7Z8I3, O43726, O75791, Q9NRB7
- UniProtKB/TrEMBL
- Q6FHA6, Q6FI14
- Conserved Domains (3) summary
-
- cd09941
Location:54 → 147
- SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
- cd11947
Location:2 → 53
- SH3_GRAP2_N; N-terminal Src homology 3 domain of GRB2-related adaptor protein 2
- cd11950
Location:275 → 327
- SH3_GRAP2_C; C-terminal Src homology 3 domain of GRB2-related adaptor protein 2
-
NM_001291825.1 → NP_001278754.1 GRB2-related adapter protein 2 isoform 1
See identical proteins and their annotated locations for NP_001278754.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1, 2 and 3 encode the same isoform 1.
- Source sequence(s)
-
AF236120, Z82206
- Consensus CDS
-
CCDS13999.1
- UniProtKB/Swiss-Prot
- B7Z8I3, O43726, O75791, Q9NRB7
- UniProtKB/TrEMBL
- Q6FHA6, Q6FI14
- Related
- ENSP00000385607.3, ENST00000407075.3
- Conserved Domains (3) summary
-
- cd09941
Location:54 → 147
- SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
- cd11947
Location:2 → 53
- SH3_GRAP2_N; N-terminal Src homology 3 domain of GRB2-related adaptor protein 2
- cd11950
Location:275 → 327
- SH3_GRAP2_C; C-terminal Src homology 3 domain of GRB2-related adaptor protein 2
-
NM_001291826.2 → NP_001278755.1 GRB2-related adapter protein 2 isoform 2
See identical proteins and their annotated locations for NP_001278755.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks an internal exon, which results in a downstream start codon, compared to variant 1. The resulting isoform (2) has a shorter N-terminus, compared to isoform 1.
- Source sequence(s)
-
AK303280, DC409651, KF457461, Z82206
- UniProtKB/TrEMBL
- B7Z8E3, B7Z8J2
- Conserved Domains (2) summary
-
- cd09941
Location:3 → 75
- SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
- cd11950
Location:203 → 255
- SH3_GRAP2_C; C-terminal Src homology 3 domain of GRB2-related adaptor protein 2
-
NM_001291828.2 → NP_001278757.1 GRB2-related adapter protein 2 isoform 3
See identical proteins and their annotated locations for NP_001278757.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks three internal exons, which results in an alternate downstream start codon, compared to variant 1. The resulting isoform (3) has a shorter and distinct N-terminus, compared to isoform 1.
- Source sequence(s)
-
AK303470, HY091328, KF457461, Z82206
- UniProtKB/Swiss-Prot
-
O75791
- Conserved Domains (1) summary
-
- cd11950
Location:162 → 214
- SH3_GRAP2_C; C-terminal Src homology 3 domain of GRB2-related adaptor protein 2
-
NM_004810.4 → NP_004801.1 GRB2-related adapter protein 2 isoform 1
See identical proteins and their annotated locations for NP_004801.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1, 2 and 3 encode the same isoform 1.
- Source sequence(s)
-
AY069959, KF457461, Z82206
- Consensus CDS
-
CCDS13999.1
- UniProtKB/Swiss-Prot
- B7Z8I3, O43726, O75791, Q9NRB7
- UniProtKB/TrEMBL
- Q6FHA6, Q6FI14
- Related
- ENSP00000339186.4, ENST00000344138.9
- Conserved Domains (3) summary
-
- cd09941
Location:54 → 147
- SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
- cd11947
Location:2 → 53
- SH3_GRAP2_N; N-terminal Src homology 3 domain of GRB2-related adaptor protein 2
- cd11950
Location:275 → 327
- SH3_GRAP2_C; C-terminal Src homology 3 domain of GRB2-related adaptor protein 2
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000022.11 Reference GRCh38.p14 Primary Assembly
- Range
-
39893820..39973721
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047441607.1 → XP_047297563.1 GRB2-related adapter protein 2 isoform X1
- UniProtKB/Swiss-Prot
- B7Z8I3, O43726, O75791, Q9NRB7
- UniProtKB/TrEMBL
- Q6FHA6, Q6FI14
-
XM_047441608.1 → XP_047297564.1 GRB2-related adapter protein 2 isoform X2
- UniProtKB/TrEMBL
- B7Z8F8, B7Z8J2
RNA
-
XR_007067995.1 RNA Sequence
-
XR_007067996.1 RNA Sequence
Alternate T2T-CHM13v2.0
Genomic
-
NC_060946.1 Alternate T2T-CHM13v2.0
- Range
-
40364806..40444710
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054326139.1 → XP_054182114.1 GRB2-related adapter protein 2 isoform X1
- UniProtKB/Swiss-Prot
- B7Z8I3, O43726, O75791, Q9NRB7
- UniProtKB/TrEMBL
- Q6FHA6, Q6FI14
-
XM_054326140.1 → XP_054182115.1 GRB2-related adapter protein 2 isoform X2
- UniProtKB/TrEMBL
- B7Z8F8, B7Z8J2
RNA
-
XR_008485437.1 RNA Sequence
-
XR_008485438.1 RNA Sequence