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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001288718.2 → NP_001275647.1 signal transducer and activator of transcription 5A isoform 1
See identical proteins and their annotated locations for NP_001275647.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Variants 1 and 2 encode the same isoform.
- Source sequence(s)
-
AB208972, AK291650, BC027036, L41142
- Consensus CDS
-
CCDS11424.1
- UniProtKB/Swiss-Prot
- P42229, Q1KLZ6
- UniProtKB/TrEMBL
- A0A384N5W4, A0A7I2YQY3
- Related
- ENSP00000468749.1, ENST00000590949.6
- Conserved Domains (4) summary
-
- cd10421
Location:573 → 712
- SH2_STAT5a; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins
- pfam01017
Location:141 → 330
- STAT_alpha; STAT protein, all-alpha domain
- pfam02864
Location:332 → 582
- STAT_bind; STAT protein, DNA binding domain
- pfam02865
Location:2 → 124
- STAT_int; STAT protein, protein interaction domain
-
NM_001288719.2 → NP_001275648.1 signal transducer and activator of transcription 5A isoform 2
See identical proteins and their annotated locations for NP_001275648.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an in-frame coding exon in the 5' region compared to variant 1. The resulting shorter isoform (2) lacks an internal protein segment compared to isoform 1.
- Source sequence(s)
-
AB208972, BC027036, DQ471288
- Consensus CDS
-
CCDS74067.1
- UniProtKB/TrEMBL
-
A0A7I2YQY3
- Related
- ENSP00000443107.1, ENST00000546010.6
- Conserved Domains (4) summary
-
- cd10421
Location:543 → 682
- SH2_STAT5a; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins
- cd16855
Location:109 → 300
- STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
- cd16849
Location:302 → 459
- STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
- pfam02865
Location:4 → 95
- STAT_int; STAT protein, protein interaction domain
-
NM_001288720.2 → NP_001275649.1 signal transducer and activator of transcription 5A isoform 3
See identical proteins and their annotated locations for NP_001275649.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks an in-frame coding exon in the 3' region compared to variant 1. The resulting shorter isoform (3) lacks an internal protein segment compared to isoform 1.
- Source sequence(s)
-
AB208972, AK291650, BC027036
- Consensus CDS
-
CCDS74066.1
- UniProtKB/TrEMBL
- K7EK35, Q59GY7
- Related
- ENSP00000465437.1, ENST00000588868.5
- Conserved Domains (4) summary
-
- cd10421
Location:542 → 681
- SH2_STAT5a; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins
- cd16855
Location:139 → 330
- STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
- cl28920
Location:332 → 460
- STAT_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription (STAT)
- pfam02865
Location:4 → 124
- STAT_int; STAT protein, protein interaction domain
-
NM_001411103.1 → NP_001398032.1 signal transducer and activator of transcription 5A isoform 4
Status: REVIEWED
- Source sequence(s)
-
AC087691, AC099811
- Consensus CDS
-
CCDS92308.1
- UniProtKB/TrEMBL
- A0A7I2YQF1, A0A8V8TP21
- Related
- ENSP00000503484.1, ENST00000676631.1
-
NM_003152.4 → NP_003143.2 signal transducer and activator of transcription 5A isoform 1
See identical proteins and their annotated locations for NP_003143.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (1).
- Source sequence(s)
-
AB208972, AK291650, BC027036, L41142, U43185
- Consensus CDS
-
CCDS11424.1
- UniProtKB/Swiss-Prot
- P42229, Q1KLZ6
- UniProtKB/TrEMBL
- A0A384N5W4, A0A7I2YQY3
- Related
- ENSP00000341208.4, ENST00000345506.8
- Conserved Domains (4) summary
-
- cd10421
Location:573 → 712
- SH2_STAT5a; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins
- pfam01017
Location:141 → 330
- STAT_alpha; STAT protein, all-alpha domain
- pfam02864
Location:332 → 582
- STAT_bind; STAT protein, DNA binding domain
- pfam02865
Location:2 → 124
- STAT_int; STAT protein, protein interaction domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000017.11 Reference GRCh38.p14 Primary Assembly
- Range
-
42287439..42311943
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047436590.1 → XP_047292546.1 signal transducer and activator of transcription 5A isoform X2
- UniProtKB/TrEMBL
-
A0A7I2YQY3
-
XM_047436589.1 → XP_047292545.1 signal transducer and activator of transcription 5A isoform X1
- UniProtKB/Swiss-Prot
- P42229, Q1KLZ6
- UniProtKB/TrEMBL
- A0A384N5W4, A0A7I2YQY3
-
XM_047436591.1 → XP_047292547.1 signal transducer and activator of transcription 5A isoform X3
- UniProtKB/TrEMBL
-
A0A8V8TP21
-
XM_047436588.1 → XP_047292544.1 signal transducer and activator of transcription 5A isoform X1
- UniProtKB/Swiss-Prot
- P42229, Q1KLZ6
- UniProtKB/TrEMBL
- A0A384N5W4, A0A7I2YQY3
Alternate T2T-CHM13v2.0
Genomic
-
NC_060941.1 Alternate T2T-CHM13v2.0
- Range
-
43143926..43168430
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054316996.1 → XP_054172971.1 signal transducer and activator of transcription 5A isoform X2
- UniProtKB/TrEMBL
-
A0A7I2YQY3
-
XM_054316995.1 → XP_054172970.1 signal transducer and activator of transcription 5A isoform X1
- UniProtKB/Swiss-Prot
- P42229, Q1KLZ6
- UniProtKB/TrEMBL
- A0A384N5W4, A0A7I2YQY3
-
XM_054316997.1 → XP_054172972.1 signal transducer and activator of transcription 5A isoform X3
- UniProtKB/TrEMBL
-
A0A8V8TP21
-
XM_054316994.1 → XP_054172969.1 signal transducer and activator of transcription 5A isoform X1
- UniProtKB/Swiss-Prot
- P42229, Q1KLZ6
- UniProtKB/TrEMBL
- A0A384N5W4, A0A7I2YQY3