These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
-
NM_001048171.2 → NP_001041636.2 adenine DNA glycosylase isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (alpha3), also known as type 1, uses an alternate in-frame splice site in the 5' coding region, compared to variant alpha5. This difference results in a protein (isoform 2) that is shorter than isoform 5. Isoform 2 has been shown to localize to mitochondria.
- Source sequence(s)
-
AL359540
- Consensus CDS
-
CCDS41322.1
- UniProtKB/TrEMBL
-
E5KP34
- Related
- ENSP00000361187.3, ENST00000372115.7
- Conserved Domains (1) summary
-
- COG1194
Location:64 → 466
- MutY; Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs [Replication, recombination and repair]
-
NM_001048172.2 → NP_001041637.1 adenine DNA glycosylase isoform 3
See identical proteins and their annotated locations for NP_001041637.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (gamma2) contains a distinct 5' UTR and uses an alternate in-frame splice site in the 5' coding region, compared to variant alpha5. These differences cause translation initiation at a downstream start codon and result in a protein (isoform 3) that is shorter than isoform 5.
- Source sequence(s)
-
AB032927, AL359540, CN413115
- Consensus CDS
-
CCDS41321.1
- UniProtKB/TrEMBL
- E5KP28, E5KP33
- Related
- ENSP00000346354.6, ENST00000354383.10
- Conserved Domains (4) summary
-
- smart00525
Location:262 → 282
- FES; iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3)
- COG1194
Location:65 → 467
- MutY; Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs [Replication, recombination and repair]
- cd00056
Location:101 → 259
- ENDO3c; endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases
- cd03431
Location:341 → 470
- DNA_Glycosylase_C; DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important ...
-
NM_001048173.2 → NP_001041638.1 adenine DNA glycosylase isoform 2
See identical proteins and their annotated locations for NP_001041638.1
Status: REVIEWED
- Source sequence(s)
-
AB032928, AL359540, CN413115
- Consensus CDS
-
CCDS41322.1
- UniProtKB/TrEMBL
-
E5KP34
- Related
- ENSP00000347685.2, ENST00000355498.6
- Conserved Domains (1) summary
-
- COG1194
Location:64 → 466
- MutY; Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs [Replication, recombination and repair]
-
NM_001048174.2 → NP_001041639.1 adenine DNA glycosylase isoform 2
See identical proteins and their annotated locations for NP_001041639.1
Status: REVIEWED
- Source sequence(s)
-
AB032925, AL359540
- Consensus CDS
-
CCDS41322.1
- UniProtKB/TrEMBL
-
E5KP34
- Related
- ENSP00000407590.2, ENST00000456914.7
- Conserved Domains (1) summary
-
- COG1194
Location:64 → 466
- MutY; Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs [Replication, recombination and repair]
-
NM_001128425.2 → NP_001121897.1 adenine DNA glycosylase isoform 5
See identical proteins and their annotated locations for NP_001121897.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (alpha5) represents the longest transcript and encodes the longest isoform (5).
- Source sequence(s)
-
AB032920, AL359540, BM926983
- UniProtKB/TrEMBL
- E5KP25, E5KP30
- Related
- ENSP00000518552.2, ENST00000710952.2
- Conserved Domains (4) summary
-
- smart00525
Location:289 → 309
- FES; iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3)
- COG1194
Location:92 → 494
- MutY; Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs [Replication, recombination and repair]
- cd00056
Location:128 → 286
- ENDO3c; endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases
- cd03431
Location:368 → 497
- DNA_Glycosylase_C; DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important ...
-
NM_001293190.2 → NP_001280119.1 adenine DNA glycosylase isoform 6
See identical proteins and their annotated locations for NP_001280119.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (alpha2) uses an alternate in-frame splice site in the 5' coding region, compared to variant alpha5. The resulting isoform (6) lacks an internal segment, compared to isoform 5.
- Source sequence(s)
-
AB032921, BM926983
- Consensus CDS
-
CCDS72777.1
- UniProtKB/TrEMBL
-
E5KP27
- Related
- ENSP00000361182.3, ENST00000372110.7
- Conserved Domains (4) summary
-
- smart00525
Location:276 → 296
- FES; iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3)
- COG1194
Location:79 → 481
- MutY; Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs [Replication, recombination and repair]
- cd00056
Location:115 → 273
- ENDO3c; endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases
- cd03431
Location:355 → 484
- DNA_Glycosylase_C; DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important ...
-
NM_001293191.2 → NP_001280120.1 adenine DNA glycosylase isoform 7
See identical proteins and their annotated locations for NP_001280120.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (beta1) contains a distinct 5' UTR, lacks a portion of the 5' coding region and also uses an alternate in-frame splice site in the 5' coding region, compared to variant alpha5. The resulting isoform (7) has a shorter N-terminus and lacks an internal 3aa segment, compared to isoform 5.
- Source sequence(s)
-
AB032924, AL359540, AL560568
- Consensus CDS
-
CCDS72776.1
- UniProtKB/TrEMBL
-
E5KP33
- Related
- ENSP00000409718.1, ENST00000448481.5
- Conserved Domains (4) summary
-
- smart00525
Location:272 → 292
- FES; iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3)
- COG1194
Location:75 → 477
- MutY; Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs [Replication, recombination and repair]
- cd00056
Location:111 → 269
- ENDO3c; endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases
- cd03431
Location:351 → 480
- DNA_Glycosylase_C; DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important ...
-
NM_001293192.2 → NP_001280121.1 adenine DNA glycosylase isoform 8
See identical proteins and their annotated locations for NP_001280121.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (alpha4) uses an alternate splice site in the 5' region, which results in translation initiation at a downstream AUG start codon, compared to variant alpha5. The resulting isoform (8) has a shorter N-terminus, compared to isoform 5. Variants alpha4 and gamma4 encode the same isoform 8.
- Source sequence(s)
-
AB032923, BM926983
- UniProtKB/TrEMBL
-
Q5T418
- Conserved Domains (4) summary
-
- TIGR01084
Location:3 → 305
- mutY; A/G-specific adenine glycosylase
- smart00525
Location:169 → 189
- FES; iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3)
- cd00056
Location:8 → 166
- ENDO3c; endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases
- cd03431
Location:248 → 377
- DNA_Glycosylase_C; DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important ...
-
NM_001293195.2 → NP_001280124.1 adenine DNA glycosylase isoform 2
See identical proteins and their annotated locations for NP_001280124.1
Status: REVIEWED
- Source sequence(s)
-
AB032926, AL359540, AL560568
- Consensus CDS
-
CCDS41322.1
- UniProtKB/TrEMBL
-
E5KP34
- Related
- ENSP00000361176.1, ENST00000372104.5
- Conserved Domains (1) summary
-
- COG1194
Location:64 → 466
- MutY; Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs [Replication, recombination and repair]
-
NM_001293196.2 → NP_001280125.1 adenine DNA glycosylase isoform 8
See identical proteins and their annotated locations for NP_001280125.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (gamma4) contains a distinct 5' UTR, and uses an alternate splice site in the 5' region, which results in translation initiation at a downstream AUG start codon, compared to variant alpha5. The resulting isoform (8) has a shorter N-terminus, compared to isoform 5. Variants alpha4 and gamma4 encode the same isoform 8.
- Source sequence(s)
-
AB032929, AL359540, BI818560, HY094590
- UniProtKB/TrEMBL
-
Q5T418
- Conserved Domains (4) summary
-
- TIGR01084
Location:3 → 305
- mutY; A/G-specific adenine glycosylase
- smart00525
Location:169 → 189
- FES; iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3)
- cd00056
Location:8 → 166
- ENDO3c; endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases
- cd03431
Location:248 → 377
- DNA_Glycosylase_C; DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important ...
-
NM_001350650.2 → NP_001337579.1 adenine DNA glycosylase isoform 9
Status: REVIEWED
- Source sequence(s)
-
BC003178, BM926983
- UniProtKB/TrEMBL
-
Q5T418
- Conserved Domains (1) summary
-
- COG1194
Location:10 → 351
- MutY; Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs [Replication, recombination and repair]
-
NM_001350651.2 → NP_001337580.1 adenine DNA glycosylase isoform 9
Status: REVIEWED
- Source sequence(s)
-
BC003178, BM926983
- UniProtKB/TrEMBL
-
Q5T418
- Conserved Domains (1) summary
-
- COG1194
Location:10 → 351
- MutY; Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs [Replication, recombination and repair]
-
NM_001407069.1 → NP_001393998.1 adenine DNA glycosylase isoform 17
Status: REVIEWED
- Source sequence(s)
-
AL359540
- UniProtKB/TrEMBL
-
E5KP31
-
NM_001407070.1 → NP_001393999.1 adenine DNA glycosylase isoform 2
Status: REVIEWED
- Source sequence(s)
-
AL359540
- UniProtKB/TrEMBL
-
E5KP34
-
NM_001407071.1 → NP_001394000.1 adenine DNA glycosylase isoform 3
Status: REVIEWED
- Source sequence(s)
-
AL359540
- UniProtKB/TrEMBL
- E5KP28, E5KP33
-
NM_001407072.1 → NP_001394001.1 adenine DNA glycosylase isoform 2
Status: REVIEWED
- Source sequence(s)
-
AL359540
- UniProtKB/TrEMBL
-
E5KP34
-
NM_001407073.1 → NP_001394002.1 adenine DNA glycosylase isoform 18
Status: REVIEWED
- Source sequence(s)
-
AL359540
- UniProtKB/TrEMBL
-
E5KP27
-
NM_001407075.1 → NP_001394004.1 adenine DNA glycosylase isoform 16
Status: REVIEWED
- Source sequence(s)
-
AL359540
- UniProtKB/TrEMBL
-
E5KP34
-
NM_001407077.1 → NP_001394006.1 adenine DNA glycosylase isoform 7
Status: REVIEWED
- Source sequence(s)
-
AL359540
- UniProtKB/TrEMBL
-
E5KP33
- Related
- ENSP00000403655.2, ENST00000435155.2
-
NM_001407078.1 → NP_001394007.1 adenine DNA glycosylase isoform 3
Status: REVIEWED
- Source sequence(s)
-
AL359540
- UniProtKB/TrEMBL
- E5KP28, E5KP33
-
NM_001407079.1 → NP_001394008.1 adenine DNA glycosylase isoform 14
Status: REVIEWED
- Source sequence(s)
-
AL359540
- UniProtKB/TrEMBL
-
E5KP33
-
NM_001407080.1 → NP_001394009.1 adenine DNA glycosylase isoform 15
Status: REVIEWED
- Source sequence(s)
-
AL359540
- UniProtKB/TrEMBL
-
E5KP34
-
NM_001407081.1 → NP_001394010.1 adenine DNA glycosylase isoform 2
Status: REVIEWED
- Source sequence(s)
-
AL359540
- UniProtKB/TrEMBL
-
E5KP34
-
NM_001407082.1 → NP_001394011.1 adenine DNA glycosylase isoform 9
Status: REVIEWED
- Source sequence(s)
-
AL359540
- UniProtKB/TrEMBL
-
Q5T418
-
NM_001407083.1 → NP_001394012.1 adenine DNA glycosylase isoform 10
Status: REVIEWED
- Source sequence(s)
-
AL359540
- UniProtKB/TrEMBL
- E5KP33, E9PM53
-
NM_001407085.1 → NP_001394014.1 adenine DNA glycosylase isoform 10
Status: REVIEWED
- Source sequence(s)
-
AL359540
- Consensus CDS
-
CCDS90938.1
- UniProtKB/TrEMBL
- E5KP33, E9PM53
- Related
- ENSP00000433130.2, ENST00000528013.6
-
NM_001407086.1 → NP_001394015.1 adenine DNA glycosylase isoform 3
Status: REVIEWED
- Source sequence(s)
-
AL359540
- Consensus CDS
-
CCDS41321.1
- UniProtKB/TrEMBL
- E5KP28, E5KP33
-
NM_001407087.1 → NP_001394016.1 adenine DNA glycosylase isoform 12
Status: REVIEWED
- Source sequence(s)
-
AL359540
- UniProtKB/TrEMBL
- A0AAQ5BGW7, E5KP33
- Related
- ENSP00000519052.1, ENST00000713751.1
-
NM_001407088.1 → NP_001394017.1 adenine DNA glycosylase isoform 2
Status: REVIEWED
- Source sequence(s)
-
AL359540
- UniProtKB/TrEMBL
-
E5KP34
- Related
- ENSP00000519051.1, ENST00000713750.1
-
NM_001407089.1 → NP_001394018.1 adenine DNA glycosylase isoform 2
Status: REVIEWED
- Source sequence(s)
-
AL359540
- UniProtKB/TrEMBL
-
E5KP34
-
NM_001407091.1 → NP_001394020.1 adenine DNA glycosylase isoform 8
Status: REVIEWED
- Source sequence(s)
-
AL359540
- UniProtKB/TrEMBL
-
Q5T418
-
NM_012222.3 → NP_036354.1 adenine DNA glycosylase isoform 1
See identical proteins and their annotated locations for NP_036354.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (alpha1) uses an alternate in-frame splice site in the 5' coding region, compared to variant alpha5. This difference results in a protein (isoform 1) that is shorter than isoform 5.
- Source sequence(s)
-
AB032920, BM926983
- Consensus CDS
-
CCDS520.1
- UniProtKB/Swiss-Prot
- D3DPZ4, Q15830, Q9UBP2, Q9UBS7, Q9UIF4, Q9UIF5, Q9UIF6, Q9UIF7
- UniProtKB/TrEMBL
- E5KP26, E5KP31
- Related
- ENSP00000500891.1, ENST00000672818.3
- Conserved Domains (4) summary
-
- smart00525
Location:286 → 306
- FES; iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3)
- COG1194
Location:89 → 491
- MutY; Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs [Replication, recombination and repair]
- cd00056
Location:125 → 283
- ENDO3c; endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases
- cd03431
Location:365 → 494
- DNA_Glycosylase_C; DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important ...