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    EXOSC8 exosome component 8 [ Bos taurus (domestic cattle) ]

    Gene ID: 532080, updated on 1-Jan-2025

    Summary

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    Official Symbol
    EXOSC8provided by VGNC
    Official Full Name
    exosome component 8provided by VGNC
    Primary source
    VGNC:VGNC:28662
    See related
    BGD:BT18874; Ensembl:ENSBTAG00000011855
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See EXOSC8 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 12 NC_037339.1 (24685656..24694910, complement)

    Chromosome 12 - NC_037339.1Genomic Context describing neighboring genes Neighboring gene serine/arginine repetitive matrix protein 1-like Neighboring gene SPT20 homolog, SAGA complex component Neighboring gene protein SPO16 homolog Neighboring gene ALG5 dolichyl-phosphate beta-glucosyltransferase Neighboring gene uncharacterized LOC101906508

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037339.1 Chromosome 12 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables mRNA 3'-UTR AU-rich region binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in TRAMP-dependent tRNA surveillance pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in U1 snRNA 3'-end processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in U4 snRNA 3'-end processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in U5 snRNA 3'-end processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear mRNA surveillance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear polyadenylation-dependent mRNA catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear polyadenylation-dependent rRNA catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of cytoplasmic exosome (RNase complex) IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of nuclear exosome (RNase complex) IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    exosome complex component RRP43
    Names
    exosome complex exonuclease RRP43
    ribosomal RNA-processing protein 43
    NP_001073074.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001079606.2 → NP_001073074.1  exosome complex component RRP43

      See identical proteins and their annotated locations for NP_001073074.1

      Status: PROVISIONAL

      Source sequence(s)
      BC112881
      UniProtKB/Swiss-Prot
      Q2KHU3
      UniProtKB/TrEMBL
      A0AAA9SAE0
      Related
      ENSBTAP00000015733.5, ENSBTAT00000015733.6
      Conserved Domains (2) summary
      cd11369
      Location:6 → 266
      RNase_PH_RRP43; RRP43 subunit of eukaryotic exosome
      COG2123
      Location:12 → 275
      Rrp42; Exosome complex RNA-binding protein Rrp42, RNase PH superfamily [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037339.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      24685656..24694910 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2KHU3.1 GenPept UniProtKB/Swiss-Prot:Q2KHU3

    Gene LinkOut

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