PDPN podoplanin [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: PDPNprovided by VGNC
Official Full Name: podoplaninprovided by VGNC
Primary source: VGNC:VGNC:50142
See related: BGD:BT15418; EnsemblRapid:ENSBTAG00070020722
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Annotation information: Annotation category: partial on reference assembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	16	NC_037343.1 (54010801..54043029, complement)

Chromosome 16 - NC_037343.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037343.1 Chromosome 16 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These results indicated that PDPN gene plays a significant role in the proliferation and maturation of bovine Sertoli cells.
Title: PDPN gene promotes the proliferation of immature Bovine Sertoli cells in vitro.

Submit: New GeneRIF Correction

General gene information

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Markers

G35737 (e-PCR)
- UniSTS:52646

D12S1612 (e-PCR)
- UniSTS:64992

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables chemokine binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein-folding chaperone binding	IEA Inferred from Electronic Annotation more info	PubMed
enables signaling receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in Rho protein signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in actin-mediated cell contraction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell-cell adhesion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in lung development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of cell migration	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of epithelial to mesenchymal transition	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of extracellular matrix disassembly	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of platelet aggregation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of lamellipodium morphogenesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of myofibroblast contraction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of substrate adhesion-dependent cell spreading	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to hyperoxia	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in apical plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in basolateral plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in filopodium	IEA Inferred from Electronic Annotation more info	PubMed
located_in lamellipodium	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: podoplanin

Names: aggrus

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.