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    ATP2B2 ATPase plasma membrane Ca2+ transporting 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 613800, updated on 30-Jan-2025

    Summary

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    Official Symbol
    ATP2B2provided by VGNC
    Official Full Name
    ATPase plasma membrane Ca2+ transporting 2provided by VGNC
    Primary source
    VGNC:VGNC:26294
    See related
    BGD:BT10210; EnsemblRapid:ENSBTAG00070026512
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Annotation information
    Annotation category: suggests misassembly
    Orthologs
    human mouse all
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    Genomic context

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    See ATP2B2 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 22 NC_037349.1 (54363223..54744518, complement)

    Chromosome 22 - NC_037349.1Genomic Context describing neighboring genes Neighboring gene ghrelin and obestatin prepropeptide Neighboring gene SEC13 homolog, nuclear pore and COPII coat complex component Neighboring gene transfer RNA lysine (anticodon UUU) Neighboring gene microRNA mir-885 Neighboring gene uncharacterized LOC104975597 Neighboring gene uncharacterized LOC132343523 Neighboring gene uncharacterized LOC132343525 Neighboring gene solute carrier family 6 member 11

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables P-type calcium transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables PDZ domain binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cytosolic calcium ion concentration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    plasma membrane calcium-transporting ATPase 2
    Names
    ATPase, Ca++ transporting, plasma membrane 4
    NP_001178174.1
    XP_024838737.1
    XP_024838739.1
    XP_024838740.1
    XP_024838741.1
    XP_024838742.1
    XP_024838743.1
    XP_024838744.1
    XP_024838747.1
    XP_024838748.1
    XP_024838749.1
    XP_024838750.1
    XP_024838751.1
    XP_059735817.1
    XP_059735818.1
    XP_059735820.1
    XP_059735821.1
    XP_059735823.1
    XP_059735824.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191245.3 → NP_001178174.1  plasma membrane calcium-transporting ATPase 2

      Status: VALIDATED

      Source sequence(s)
      NKLS02000022
      UniProtKB/TrEMBL
      A0AAA9TSU8
      Related
      ENSBTAP00070035840.1, ENSBTAT00070060407.1
      Conserved Domains (2) summary
      pfam12424
      Location:1081 → 1127
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
      cl27747
      Location:12 → 1042
      E1-E2_ATPase; E1-E2 ATPase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037349.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      54363223..54744518 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024982981.2 → XP_024838749.1  plasma membrane calcium-transporting ATPase 2 isoform X4

      UniProtKB/TrEMBL
      F1MN60
      Conserved Domains (2) summary
      pfam12424
      Location:1126 → 1166
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
      cl27747
      Location:12 → 1087
      E1-E2_ATPase; E1-E2 ATPase

    2. XM_059879841.1 → XP_059735824.1  plasma membrane calcium-transporting ATPase 2 isoform X8

      UniProtKB/TrEMBL
      A0A3Q1LKB5
      Related
      ENSBTAP00070035721.1, ENSBTAT00070060202.1

    3. XM_024982980.2 → XP_024838748.1  plasma membrane calcium-transporting ATPase 2 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1LUI4, A0AAA9TSU8
      Related
      ENSBTAP00070035794.1, ENSBTAT00070060332.1
      Conserved Domains (2) summary
      pfam12424
      Location:1095 → 1141
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
      cl27747
      Location:12 → 1056
      E1-E2_ATPase; E1-E2 ATPase

    4. XM_059879840.1 → XP_059735823.1  plasma membrane calcium-transporting ATPase 2 isoform X7

      UniProtKB/TrEMBL
      A0A3Q1LKB5

    5. XM_024982979.2 → XP_024838747.1  plasma membrane calcium-transporting ATPase 2 isoform X2

      UniProtKB/TrEMBL
      A0AAA9TSU8, A0AAA9TTZ6
      Related
      ENSBTAP00070035778.1, ENSBTAT00070060309.1
      Conserved Domains (2) summary
      pfam12424
      Location:1106 → 1152
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
      cl27747
      Location:12 → 1067
      E1-E2_ATPase; E1-E2 ATPase

    6. XM_024982969.2 → XP_024838737.1  plasma membrane calcium-transporting ATPase 2 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TEJ1, A0AAA9TSU8
      Related
      ENSBTAP00070035774.1, ENSBTAT00070060295.1
      Conserved Domains (2) summary
      pfam12424
      Location:1126 → 1172
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
      cl27747
      Location:12 → 1087
      E1-E2_ATPase; E1-E2 ATPase

    7. XM_059879835.1 → XP_059735818.1  plasma membrane calcium-transporting ATPase 2 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TEJ1, A0AAA9TSU8

    8. XM_059879834.1 → XP_059735817.1  plasma membrane calcium-transporting ATPase 2 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TEJ1, A0AAA9TSU8

    9. XM_059879838.1 → XP_059735821.1  plasma membrane calcium-transporting ATPase 2 isoform X6

      UniProtKB/TrEMBL
      A0AAA9TSU8

    10. XM_024982972.2 → XP_024838740.1  plasma membrane calcium-transporting ATPase 2 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TEJ1, A0AAA9TSU8
      Conserved Domains (2) summary
      pfam12424
      Location:1126 → 1172
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
      cl27747
      Location:12 → 1087
      E1-E2_ATPase; E1-E2 ATPase

    11. XM_024982975.2 → XP_024838743.1  plasma membrane calcium-transporting ATPase 2 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TEJ1, A0AAA9TSU8
      Conserved Domains (2) summary
      pfam12424
      Location:1126 → 1172
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
      cl27747
      Location:12 → 1087
      E1-E2_ATPase; E1-E2 ATPase

    12. XM_024982974.2 → XP_024838742.1  plasma membrane calcium-transporting ATPase 2 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TEJ1, A0AAA9TSU8
      Conserved Domains (2) summary
      pfam12424
      Location:1126 → 1172
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
      cl27747
      Location:12 → 1087
      E1-E2_ATPase; E1-E2 ATPase

    13. XM_059879837.1 → XP_059735820.1  plasma membrane calcium-transporting ATPase 2 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TEJ1, A0AAA9TSU8

    14. XM_024982971.2 → XP_024838739.1  plasma membrane calcium-transporting ATPase 2 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TEJ1, A0AAA9TSU8
      Conserved Domains (2) summary
      pfam12424
      Location:1126 → 1172
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
      cl27747
      Location:12 → 1087
      E1-E2_ATPase; E1-E2 ATPase

    15. XM_024982983.2 → XP_024838751.1  plasma membrane calcium-transporting ATPase 2 isoform X6

      UniProtKB/TrEMBL
      A0AAA9TSU8
      Conserved Domains (2) summary
      pfam12424
      Location:1081 → 1127
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
      cl27747
      Location:12 → 1042
      E1-E2_ATPase; E1-E2 ATPase

    16. XM_024982973.2 → XP_024838741.1  plasma membrane calcium-transporting ATPase 2 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TEJ1, A0AAA9TSU8
      Conserved Domains (2) summary
      pfam12424
      Location:1126 → 1172
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
      cl27747
      Location:12 → 1087
      E1-E2_ATPase; E1-E2 ATPase

    17. XM_024982976.2 → XP_024838744.1  plasma membrane calcium-transporting ATPase 2 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TEJ1, A0AAA9TSU8
      Conserved Domains (2) summary
      pfam12424
      Location:1126 → 1172
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
      cl27747
      Location:12 → 1087
      E1-E2_ATPase; E1-E2 ATPase

    18. XM_024982982.2 → XP_024838750.1  plasma membrane calcium-transporting ATPase 2 isoform X5

      UniProtKB/TrEMBL
      F1MN60
      Related
      ENSBTAP00070035675.1, ENSBTAT00070060116.1
      Conserved Domains (2) summary
      pfam12424
      Location:1126 → 1166
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
      cl27747
      Location:12 → 1087
      E1-E2_ATPase; E1-E2 ATPase
    Nucleotide Protein Strain
    Heading Accession and Version

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