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    ACOX2 acyl-CoA oxidase 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 514969, updated on 29-Jan-2025

    Summary

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    Official Symbol
    ACOX2provided by VGNC
    Official Full Name
    acyl-CoA oxidase 2provided by VGNC
    Primary source
    VGNC:VGNC:25553
    See related
    BGD:BT12195; Ensembl:ENSBTAG00000004178
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ACOX2 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 22 NC_037349.1 (42836573..42867389)

    Chromosome 22 - NC_037349.1Genomic Context describing neighboring genes Neighboring gene FAM3 metabolism regulating signaling molecule D Neighboring gene family with sequence similarity 107 member A Neighboring gene potassium channel tetramerization domain containing 6 Neighboring gene pyruvate dehydrogenase E1 subunit beta

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC159638

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables FAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables fatty acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables palmitoyl-CoA oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fatty acid beta-oxidation using acyl-CoA oxidase IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in very long-chain fatty acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    peroxisomal acyl-coenzyme A oxidase 2
    Names
    acyl-Coenzyme A oxidase 2, branched chain
    NP_001095485.1
    XP_015315051.1
    XP_015315052.1
    XP_015315053.1
    XP_015315054.1
    XP_015315056.1
    XP_015315057.1
    XP_015315058.1
    XP_015315061.1
    XP_015315062.1
    XP_015315063.1
    XP_024838423.1
    XP_024838425.1
    XP_024838426.1
    XP_059735609.1
    XP_059735611.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102015.2 → NP_001095485.1  peroxisomal acyl-coenzyme A oxidase 2

      See identical proteins and their annotated locations for NP_001095485.1

      Status: PROVISIONAL

      Source sequence(s)
      BC149571
      UniProtKB/TrEMBL
      A6QPZ7, F1MRF5
      Conserved Domains (2) summary
      PLN02443
      Location:26 → 682
      PLN02443; acyl-coenzyme A oxidase
      cl09933
      Location:21 → 656
      ACAD; Acyl-CoA dehydrogenase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037349.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      42836573..42867389
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015459571.3 → XP_015315057.1  peroxisomal acyl-coenzyme A oxidase 2 isoform X2

      UniProtKB/TrEMBL
      F1MRF5
      Conserved Domains (2) summary
      PLN02443
      Location:26 → 743
      PLN02443; acyl-coenzyme A oxidase
      cl09933
      Location:21 → 717
      ACAD; Acyl-CoA dehydrogenase

    2. XM_059879628.1 → XP_059735611.1  peroxisomal acyl-coenzyme A oxidase 2 isoform X5

      UniProtKB/TrEMBL
      F1MRF5
      Related
      ENSBTAP00070047771.1, ENSBTAT00070078369.1

    3. XM_015459576.3 → XP_015315062.1  peroxisomal acyl-coenzyme A oxidase 2 isoform X2

      UniProtKB/TrEMBL
      F1MRF5
      Conserved Domains (2) summary
      PLN02443
      Location:26 → 743
      PLN02443; acyl-coenzyme A oxidase
      cl09933
      Location:21 → 717
      ACAD; Acyl-CoA dehydrogenase

    4. XM_015459570.3 → XP_015315056.1  peroxisomal acyl-coenzyme A oxidase 2 isoform X2

      UniProtKB/TrEMBL
      F1MRF5
      Conserved Domains (2) summary
      PLN02443
      Location:26 → 743
      PLN02443; acyl-coenzyme A oxidase
      cl09933
      Location:21 → 717
      ACAD; Acyl-CoA dehydrogenase

    5. XM_015459567.3 → XP_015315053.1  peroxisomal acyl-coenzyme A oxidase 2 isoform X2

      UniProtKB/TrEMBL
      F1MRF5
      Conserved Domains (2) summary
      PLN02443
      Location:26 → 743
      PLN02443; acyl-coenzyme A oxidase
      cl09933
      Location:21 → 717
      ACAD; Acyl-CoA dehydrogenase

    6. XM_015459566.3 → XP_015315052.1  peroxisomal acyl-coenzyme A oxidase 2 isoform X2

      UniProtKB/TrEMBL
      F1MRF5
      Conserved Domains (2) summary
      PLN02443
      Location:26 → 743
      PLN02443; acyl-coenzyme A oxidase
      cl09933
      Location:21 → 717
      ACAD; Acyl-CoA dehydrogenase

    7. XM_015459577.3 → XP_015315063.1  peroxisomal acyl-coenzyme A oxidase 2 isoform X3

      UniProtKB/TrEMBL
      F1MRF5
      Conserved Domains (1) summary
      cl09933
      Location:21 → 673
      ACAD; Acyl-CoA dehydrogenase

    8. XM_015459572.3 → XP_015315058.1  peroxisomal acyl-coenzyme A oxidase 2 isoform X2

      UniProtKB/TrEMBL
      F1MRF5
      Conserved Domains (2) summary
      PLN02443
      Location:26 → 743
      PLN02443; acyl-coenzyme A oxidase
      cl09933
      Location:21 → 717
      ACAD; Acyl-CoA dehydrogenase

    9. XM_015459565.3 → XP_015315051.1  peroxisomal acyl-coenzyme A oxidase 2 isoform X1

      UniProtKB/TrEMBL
      F1MRF5
      Conserved Domains (2) summary
      PLN02443
      Location:34 → 751
      PLN02443; acyl-coenzyme A oxidase
      cl09933
      Location:29 → 725
      ACAD; Acyl-CoA dehydrogenase

    10. XM_024982655.2 → XP_024838423.1  peroxisomal acyl-coenzyme A oxidase 2 isoform X4

      UniProtKB/TrEMBL
      A0AAA9TCA5, F1MRF5
      Conserved Domains (1) summary
      cl09933
      Location:29 → 664
      ACAD; Acyl-CoA dehydrogenase

    11. XM_015459568.3 → XP_015315054.1  peroxisomal acyl-coenzyme A oxidase 2 isoform X2

      UniProtKB/TrEMBL
      F1MRF5
      Conserved Domains (2) summary
      PLN02443
      Location:26 → 743
      PLN02443; acyl-coenzyme A oxidase
      cl09933
      Location:21 → 717
      ACAD; Acyl-CoA dehydrogenase

    12. XM_024982657.2 → XP_024838425.1  peroxisomal acyl-coenzyme A oxidase 2 isoform X5

      UniProtKB/TrEMBL
      F1MRF5
      Conserved Domains (1) summary
      cl09933
      Location:21 → 656
      ACAD; Acyl-CoA dehydrogenase

    13. XM_059879626.1 → XP_059735609.1  peroxisomal acyl-coenzyme A oxidase 2 isoform X2

      UniProtKB/TrEMBL
      F1MRF5

    14. XM_015459575.3 → XP_015315061.1  peroxisomal acyl-coenzyme A oxidase 2 isoform X2

      UniProtKB/TrEMBL
      F1MRF5
      Conserved Domains (2) summary
      PLN02443
      Location:26 → 743
      PLN02443; acyl-coenzyme A oxidase
      cl09933
      Location:21 → 717
      ACAD; Acyl-CoA dehydrogenase

    15. XM_024982658.2 → XP_024838426.1  peroxisomal acyl-coenzyme A oxidase 2 isoform X5

      UniProtKB/TrEMBL
      F1MRF5
      Conserved Domains (1) summary
      cl09933
      Location:21 → 656
      ACAD; Acyl-CoA dehydrogenase
    Nucleotide Protein Strain
    Heading Accession and Version

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