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    PRDX2 peroxiredoxin 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 286793, updated on 29-Jan-2025

    Summary

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    Official Symbol
    PRDX2provided by VGNC
    Official Full Name
    peroxiredoxin 2provided by VGNC
    Primary source
    VGNC:VGNC:33300
    See related
    BGD:BT10759; Ensembl:ENSBTAG00000012062
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PRDX2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (12730404..12733442)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene retbindin Neighboring gene ribonuclease H2 subunit A Neighboring gene JunB proto-oncogene, AP-1 transcription factor subunit Neighboring gene hook microtubule tethering protein 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Cloning of bovine peroxiredoxins-gene expression in bovine tissues and amino acid sequence comparison with rat, mouse and primate peroxiredoxins. Leyens G, et al. Comp Biochem Physiol B Biochem Mol Biol, 2003 Dec. PMID 14662316
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables thioredoxin peroxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell redox homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in hydrogen peroxide catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in leukocyte activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in removal of superoxide radicals IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    peroxiredoxin-2
    Names
    thioredoxin-dependent peroxiredoxin 2
    NP_777188.1
    XP_005208710.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174763.2 → NP_777188.1  peroxiredoxin-2

      See identical proteins and their annotated locations for NP_777188.1

      Status: PROVISIONAL

      Source sequence(s)
      AF305562
      UniProtKB/Swiss-Prot
      Q3T0L0, Q9BGI3
      UniProtKB/TrEMBL
      A0AAA9RUA3
      Conserved Domains (1) summary
      cd03015
      Location:9 → 180
      PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      12730404..12733442
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005208653.3 → XP_005208710.1  peroxiredoxin-2 isoform X1

      See identical proteins and their annotated locations for XP_005208710.1

      UniProtKB/Swiss-Prot
      Q3T0L0, Q9BGI3
      UniProtKB/TrEMBL
      A0AAA9RUA3
      Related
      ENSBTAP00070021324.1, ENSBTAT00070036259.1
      Conserved Domains (1) summary
      cd03015
      Location:9 → 180
      PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9BGI3.1 GenPept UniProtKB/Swiss-Prot:Q9BGI3

    Gene LinkOut

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