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    PKN1 protein kinase N1 [ Bos taurus (domestic cattle) ]

    Gene ID: 509080, updated on 30-Jan-2025

    Summary

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    Official Symbol
    PKN1provided by VGNC
    Official Full Name
    protein kinase N1provided by VGNC
    Primary source
    VGNC:VGNC:32945
    See related
    EnsemblRapid:ENSBTAG00070015037
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PKN1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (11304842..11333471, complement)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene small EDRK-rich factor 1-like Neighboring gene DnaJ heat shock protein family (Hsp40) member B1 Neighboring gene GIPC PDZ domain containing family member 1 Neighboring gene prostaglandin E receptor 1 Neighboring gene DExD-box helicase 39A Neighboring gene adhesion G protein-coupled receptor E5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC142408

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase N1
    Names
    protein kinase C-like 1
    protein kinase C-like PKN
    protein kinase PKN-alpha
    protein-kinase C-related kinase 1
    serine-threonine protein kinase N
    NP_001073715.1
    XP_024849826.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080246.1 → NP_001073715.1  serine/threonine-protein kinase N1

      See identical proteins and their annotated locations for NP_001073715.1

      Status: PROVISIONAL

      Source sequence(s)
      BC126539
      UniProtKB/Swiss-Prot
      A1A4I4
      UniProtKB/TrEMBL
      F1MFG6
      Related
      ENSBTAP00070020165.1, ENSBTAT00070034005.1
      Conserved Domains (6) summary
      cd08687
      Location:391 → 477
      C2_PKN-like; C2 domain in Protein kinase C-like (PKN) proteins
      cd11622
      Location:46 → 98
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11630
      Location:122 → 197
      HR1_PKN1_2; Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N1
      cd11636
      Location:206 → 279
      HR1_PKN1_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N1
      smart00220
      Location:617 → 876
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05589
      Location:617 → 941
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      11304842..11333471 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024994058.2 → XP_024849826.1  serine/threonine-protein kinase N1 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TRQ6, F1MFG6
      Related
      ENSBTAP00070020152.1, ENSBTAT00070033988.1
      Conserved Domains (5) summary
      cd08687
      Location:397 → 483
      C2_PKN-like; C2 domain in Protein kinase C-like (PKN) proteins
      cd11622
      Location:52 → 104
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11630
      Location:128 → 203
      HR1_PKN1_2; Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N1
      cd05589
      Location:623 → 947
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl00087
      Location:212 → 285
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1A4I4.1 GenPept UniProtKB/Swiss-Prot:A1A4I4

    Gene LinkOut

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